Literature DB >> 19714384

Scintigraphic evaluation of gastric emptying in obese patients submitted to sleeve gastrectomy compared to normal subjects.

Italo Braghetto1, Cristóbal Davanzo, Owen Korn, Attila Csendes, Héctor Valladares, Eduardo Herrera, Patricio Gonzalez, Karin Papapietro.   

Abstract

BACKGROUND: Sleeve gastrectomy (SG) has been accepted as an option for surgical treatment for obesity. This operation could be associated with motor gastric dysfunction and abnormal gastric emptying. The purpose of this prospective study is to present the results of gastric emptying to liquids and solids using scintigraphy in patients who underwent SG compared to normal subjects.
METHODS: Twenty obese patients were submitted to laparoscopic SG and were compared to 18 normal subjects. Gastric emptying of liquids and solids was measured by scintigraphic technique. Results were expressed as half time of gastric emptying and the percentage of retention at 20, 30, and 60 min for liquids and at 60, 90, and 120 min for solids.
RESULTS: In the group of operated patients, 70% of them (n = 14) presented accelerated emptying for liquids and 75% (n = 15) for solids compared to 22.2% and 27.7%, respectively, in the control group. The half time of gastric emptying (T (1/2)) in patients submitted to SG both for liquids and solids were significantly more accelerated compared to the control group (34.9 +/- 24.6 vs 13.6 +/- 11.9 min for liquids and 78 +/- 15.01 vs 38.3 +/- 18.77 min for solids; p < 0.01). The gastric emptying for liquids expressed as the percentage of retention at 20, 30, and 60 min was 30.0 +/- 0.25%, 15.4 +/- 0.18%, and 5.7 +/- 0.10%, respectively, in operated patients, significantly less than the control subjects (p < 0.001). For solids, the percentage of retention at 60, 90, and 120 min was 56 +/- 28%, 34 +/- 22%, and 12 +/- 8%, respectively, for controls, while it was 25.3 +/- 0.20%, 9 +/- 0.12%, and 3 +/- 0.05%, respectively, in operated patients (p < 001).
CONCLUSIONS: Gastric emptying after SG is accelerated either for liquids as well as for solids in the majority of patients. These results could be taken in consideration for the dietary indications after surgery and could play a significant role in the definitive results during the late follow-up.

Entities:  

Mesh:

Year:  2009        PMID: 19714384     DOI: 10.1007/s11695-009-9954-z

Source DB:  PubMed          Journal:  Obes Surg        ISSN: 0960-8923            Impact factor:   4.129


  37 in total

1.  Early and late results of the acid suppression and duodenal diversion operation in patients with barrett's esophagus: analysis of 210 cases.

Authors:  Attila Csendes; Patricio Burdiles; Italo Braghetto; Owen Korn; Juan Carlos Díaz; Jorge Rojas
Journal:  World J Surg       Date:  2002-03-01       Impact factor: 3.352

2.  Ghrelin levels and sleeve gastrectomy in super-super-obesity.

Authors:  Régis Cohen; Bernard Uzzan; Hélène Bihan; Inès Khochtali; Gérard Reach; Jean Marc Catheline
Journal:  Obes Surg       Date:  2005 Nov-Dec       Impact factor: 4.129

3.  Gastric emptying of solids in morbid obesity.

Authors:  C Tosetti; R Corinaldesi; V Stanghellini; R Pasquali; C Corbelli; G Zoccoli; G Di Febo; N Monetti; L Barbara
Journal:  Int J Obes Relat Metab Disord       Date:  1996-03

Review 4.  Gastric motility.

Authors:  Arthi Sanjeevi
Journal:  Curr Opin Gastroenterol       Date:  2007-11       Impact factor: 3.287

Review 5.  Gastric motor disorders.

Authors:  J Tack
Journal:  Best Pract Res Clin Gastroenterol       Date:  2007       Impact factor: 3.043

6.  Type 2 diabetes mellitus and the metabolic syndrome following sleeve gastrectomy in severely obese subjects.

Authors:  J Vidal; A Ibarzabal; F Romero; S Delgado; D Momblán; L Flores; A Lacy
Journal:  Obes Surg       Date:  2008-06-03       Impact factor: 4.129

Review 7.  Alterations of gastrointestinal motility in obesity.

Authors:  Jinhong Xing; Jiande D Z Chen
Journal:  Obes Res       Date:  2004-11

8.  Gastric emptying of solids and semi-solids in morbidly obese and non-obese subjects: an assessment using the 13C-octanoic acid and 13C-acetic acid breath tests.

Authors:  Aloísio Cardoso-Júnior; Luiz Gonzaga Vaz Coelho; Paulo Roberto Savassi-Rocha; Maria Cristina Vignolo; Marcelo Militão Abrantes; Aline Miranda de Almeida; Emanuela Eudes Dias; Gerival Vieira; Mariana Moreira de Castro; Yara Vieira Lemos
Journal:  Obes Surg       Date:  2007-02       Impact factor: 4.129

9.  Gastric emptying is not affected by sleeve gastrectomy--scintigraphic evaluation of gastric emptying after sleeve gastrectomy without removal of the gastric antrum.

Authors:  Hanna Bernstine; Ronit Tzioni-Yehoshua; David Groshar; Nahum Beglaibter; Scott Shikora; Raul J Rosenthal; Moshe Rubin
Journal:  Obes Surg       Date:  2008-12-17       Impact factor: 4.129

Review 10.  Implications of altered gastrointestinal motility in obesity.

Authors:  T K Gallagher; J G Geoghegan; A W Baird; D C Winter
Journal:  Obes Surg       Date:  2007-10       Impact factor: 4.129

View more
  101 in total

1.  Effect of Roux-en-Y gastric bypass vs sleeve gastrectomy on glucose and gut hormones: a prospective randomised trial.

Authors:  José Manuel Ramón; Silvia Salvans; Xenia Crous; Sonia Puig; Albert Goday; David Benaiges; Lourdes Trillo; Manuel Pera; Luis Grande
Journal:  J Gastrointest Surg       Date:  2012-03-09       Impact factor: 3.452

2.  Pre- and postoperative nutritional deficiencies in obese patients undergoing laparoscopic sleeve gastrectomy.

Authors:  Antje Damms-Machado; Asja Friedrich; Klaus Michael Kramer; Katrin Stingel; Tobias Meile; Markus A Küper; Alfred Königsrainer; Stephan C Bischoff
Journal:  Obes Surg       Date:  2012-06       Impact factor: 4.129

3.  Food tolerance and gastrointestinal quality of life following three bariatric procedures: adjustable gastric banding, Roux-en-Y gastric bypass, and sleeve gastrectomy.

Authors:  Shannon Elise Overs; Rebecca Anne Freeman; Nazy Zarshenas; Karen Louise Walton; John Oskar Jorgensen
Journal:  Obes Surg       Date:  2012-04       Impact factor: 4.129

4.  Sleeve gastrectomy plus side-to-side jejunoileal anastomosis for the treatment of morbid obesity and metabolic diseases: a promising operation.

Authors:  John Melissas; Anastasia Peppe; John Askoxilakis; Efstathios Dimitriadis; John Grammatikakis
Journal:  Obes Surg       Date:  2012-07       Impact factor: 4.129

Review 5.  Trends in oral drug bioavailability following bariatric surgery: examining the variable extent of impact on exposure of different drug classes.

Authors:  Adam S Darwich; Kathryn Henderson; Angela Burgin; Nicola Ward; Janet Whittam; Basil J Ammori; Darren M Ashcroft; Amin Rostami-Hodjegan
Journal:  Br J Clin Pharmacol       Date:  2012-11       Impact factor: 4.335

6.  Time-resolved MRI after ingestion of liquids reveals motility changes after laparoscopic sleeve gastrectomy--preliminary results.

Authors:  Tobias Baumann; Simon Kuesters; Jodok Grueneberger; Goran Marjanovic; Lisa Zimmermann; Arnd-Oliver Schaefer; Ulrich Theodor Hopt; Mathias Langer; Wojciech Konrad Karcz
Journal:  Obes Surg       Date:  2011-01       Impact factor: 4.129

7.  Erosive esophagitis after bariatric surgery: banded vertical gastrectomy versus banded Roux-en-Y gastric bypass.

Authors:  Gustavo Peixoto Soares Miguel; João Luiz Moreira Coutinho Azevedo; Paulo Henrique Oliveira de Souza; João de Siqueira Neto; Felipe Mustafa; Evelyn Saiter Zambrana; Perseu Seixas de Carvalho
Journal:  Obes Surg       Date:  2011-02       Impact factor: 4.129

8.  Tests of correlation between immediate postoperative gastroduodenal transit times and weight loss after laparoscopic sleeve gastrectomy.

Authors:  Manish Parikh; Joseph Eisner; Nicole Hindman; Emil Balthazar; John K Saunders
Journal:  Surg Endosc       Date:  2012-05-31       Impact factor: 4.584

9.  Dumping symptoms and incidence of hypoglycaemia after provocation test at 6 and 12 months after laparoscopic sleeve gastrectomy.

Authors:  Dimitris Papamargaritis; George Koukoulis; Eleni Sioka; Eleni Zachari; Alexandra Bargiota; Dimitris Zacharoulis; George Tzovaras
Journal:  Obes Surg       Date:  2012-10       Impact factor: 4.129

10.  Influence of antrum size on gastric emptying and weight-loss outcomes after laparoscopic sleeve gastrectomy (preliminary analysis of a randomized trial).

Authors:  Meritxell Garay; Carmen Balagué; Carlos Rodríguez-Otero; Berta Gonzalo; Anna Domenech; Juan Carlos Pernas; Ignasi J Gich; Inka Miñambres; Sonia Fernández-Ananín; Eduardo M Targarona
Journal:  Surg Endosc       Date:  2018-01-08       Impact factor: 4.584

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.