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Literature DB >> 8644756

Affecteds-only linkage methods are not a panacea.

D A Greenberg, S E Hodge, V J Vieland, M A Spence.

Abstract

Mesh：

Year: 1996 PMID： 8644756 PMCID： PMC1914670

Source DB: PubMed Journal: Am J Hum Genet ISSN： 0002-9297 Impact factor: 11.025

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28 in total

1. TDT with covariates and genomic screens with mod scores: their behavior on simulated data.

Authors: J P Rice; R J Neuman; S L Hoshaw; E W Daw; C Gu
Journal: Genet Epidemiol Date: 1995 Impact factor: 2.135

2. Genetic analysis of a common oligogenic trait with quantitative correlates: summary of GAW9 results.

Authors: J Blangero
Journal: Genet Epidemiol Date: 1995 Impact factor: 2.135

3. Lods, wrods, and mods: the interpretation of lod scores calculated under different models.

Authors: S E Hodge; R C Elston
Journal: Genet Epidemiol Date: 1994 Impact factor: 2.135

4. The affected-pedigree-member method: power to detect linkage.

Authors: D E Weeks; L D Harby
Journal: Hum Hered Date: 1995 Jan-Feb Impact factor: 0.444

5. Model-free linkage analysis using likelihoods.

Authors: D Curtis; P C Sham
Journal: Am J Hum Genet Date: 1995-09 Impact factor: 11.025

6. Using lod-score differences to determine mode of inheritance: a simple, robust method even in the presence of heterogeneity and reduced penetrance.

Authors: D A Greenberg; B Berger
Journal: Am J Hum Genet Date: 1994-10 Impact factor: 11.025

7. Evaluation of screening strategies to detect an oligogenic disease.

Authors: J J Rogus; J L Haines
Journal: Genet Epidemiol Date: 1995 Impact factor: 2.135

8. Scanning chromosome 17 for psoriasis susceptibility: lack of evidence for a distal 17q locus.

Authors: R P Nair; S W Guo; S Jenisch; T Henseler; E M Lange; M Terhune; E Westphal; E Christophers; J J Voorhees; J T Elder
Journal: Hum Hered Date: 1995 Jul-Aug Impact factor: 0.444

9. Mapping of genes predisposing to idiopathic generalized epilepsy.

Authors: F Zara; A Bianchi; G Avanzini; S Di Donato; B Castellotti; P I Patel; M Pandolfo
Journal: Hum Mol Genet Date: 1995-07 Impact factor: 6.150

10. Schizophrenia and GABAA receptor subunit genes.

Authors: W Byerley; M E Bailey; A A Hicks; B P Riley; M G Darlison; J Holik; M Hoff; F Umar; F Reimherr; P Wender
Journal: Psychiatr Genet Date: 1995 Impact factor: 2.458

13 in total

1. Linkage analysis in the presence of errors IV: joint pseudomarker analysis of linkage and/or linkage disequilibrium on a mixture of pedigrees and singletons when the mode of inheritance cannot be accurately specified.

Authors: H H Göring; J D Terwilliger
Journal: Am J Hum Genet Date: 2000-03-23 Impact factor: 11.025

10. Linkage of type 2 diabetes mellitus and of age at onset to a genetic location on chromosome 10q in Mexican Americans.

Authors: R Duggirala; J Blangero; L Almasy; T D Dyer; K L Williams; R J Leach; P O'Connell; M P Stern
Journal: Am J Hum Genet Date: 1999-04 Impact factor: 11.025

Affecteds-only linkage methods are not a panacea.

1. TDT with covariates and genomic screens with mod scores: their behavior on simulated data.

2. Genetic analysis of a common oligogenic trait with quantitative correlates: summary of GAW9 results.

3. Lods, wrods, and mods: the interpretation of lod scores calculated under different models.

4. The affected-pedigree-member method: power to detect linkage.

5. Model-free linkage analysis using likelihoods.

6. Using lod-score differences to determine mode of inheritance: a simple, robust method even in the presence of heterogeneity and reduced penetrance.

7. Evaluation of screening strategies to detect an oligogenic disease.

8. Scanning chromosome 17 for psoriasis susceptibility: lack of evidence for a distal 17q locus.

9. Mapping of genes predisposing to idiopathic generalized epilepsy.

10. Schizophrenia and GABAA receptor subunit genes.

1. Linkage analysis in the presence of errors IV: joint pseudomarker analysis of linkage and/or linkage disequilibrium on a mixture of pedigrees and singletons when the mode of inheritance cannot be accurately specified.

2. The emperor's new methods.

3. Reports of the death of the epistasis model are greatly exaggerated.

4. The power and robustness of maximum LOD score statistics.

5. Nonparametric linkage tests are model free.

6. Absence of linkage of phonological coding dyslexia to chromosome 6p23-p21.3 in a large family data set.

7. Further evidence for the increased power of LOD scores compared with nonparametric methods.

8. Magnitude of type I error when single-locus linkage analysis is maximized over models: a simulation study.

9. LOD wars: the affected-sib-pair paradigm strikes back!

10. Linkage of type 2 diabetes mellitus and of age at onset to a genetic location on chromosome 10q in Mexican Americans.