Literature DB >> 8787990

TDT with covariates and genomic screens with mod scores: their behavior on simulated data.

J P Rice1, R J Neuman, S L Hoshaw, E W Daw, C Gu.   

Abstract

We describe an extension to the TDT (transmission/disequilibrium test) which allows for more than two marker alleles and for covariates measured on the parent or offspring. We also describe a systematic genomic search where the mod score (maximized lod score) is computed for each marker under constraints on the population prevalence or penetrances of a single locus.

Mesh：

Year:  1995        PMID： 8787990     DOI： 10.1002/gepi.1370120623

Source DB:  PubMed          Journal:  Genet Epidemiol        ISSN： 0741-0395            Impact factor:   2.135


  9 in total

1.  Assessment of parent-of-origin effects in linkage analysis of quantitative traits.

Authors:  R L Hanson; S Kobes; R S Lindsay; W C Knowler
Journal:  Am J Hum Genet       Date:  2001-03-13       Impact factor: 11.025

2.  Power comparison of parametric and nonparametric linkage tests in small pedigrees.

Authors:  P C Sham; M W Lin; J H Zhao; D Curtis
Journal:  Am J Hum Genet       Date:  2000-04-11       Impact factor: 11.025

3.  A perspective on epistasis: limits of models displaying no main effect.

Authors:  Robert Culverhouse; Brian K Suarez; Jennifer Lin; Theodore Reich
Journal:  Am J Hum Genet       Date:  2002-01-08       Impact factor: 11.025

Review 4.  Review and evaluation of methods correcting for population stratification with a focus on underlying statistical principles.

Authors:  Hemant K Tiwari; Jill Barnholtz-Sloan; Nathan Wineinger; Miguel A Padilla; Laura K Vaughan; David B Allison
Journal:  Hum Hered       Date:  2008-03-31       Impact factor: 0.444

5.  Affecteds-only linkage methods are not a panacea.

Authors:  D A Greenberg; S E Hodge; V J Vieland; M A Spence
Journal:  Am J Hum Genet       Date:  1996-04       Impact factor: 11.025

6.  Transmission/disequilibrium tests for multiallelic loci.

Authors:  P Sham
Journal:  Am J Hum Genet       Date:  1997-09       Impact factor: 11.025

Review 7.  The TDT and other family-based tests for linkage disequilibrium and association.

Authors:  R S Spielman; W J Ewens
Journal:  Am J Hum Genet       Date:  1996-11       Impact factor: 11.025

8.  Innovative approach to identify multigenomic and environmental interactions associated with birth defects in family-based hybrid designs.

Authors:  Xiang-Yang Lou; Ting-Ting Hou; Shou-Ye Liu; Hai-Ming Xu; Feng Lin; Xinyu Tang; Stewart L MacLeod; Mario A Cleves; Charlotte A Hobbs
Journal:  Genet Epidemiol       Date:  2020-09-30       Impact factor: 2.344

9.  Application of association mapping to understanding the genetic diversity of plant germplasm resources.

Authors:  Ibrokhim Y Abdurakhmonov; Abdusattor Abdukarimov
Journal:  Int J Plant Genomics       Date:  2008
  9 in total

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