Literature DB >> 8787995

Genetic analysis of a common oligogenic trait with quantitative correlates: summary of GAW9 results.

J Blangero1.   

Abstract

The statistical genetic analyses of a simulated data set for Genetic Analysis Workshop 9 Problem 2 are summarized. A diverse set of methods are evaluated with regard to the success with which they were able to determine the mode of inheritance and locate the genes underlying an oligogenically determined disease and four related quantitative traits.

Mesh：

Year:  1995        PMID： 8787995     DOI： 10.1002/gepi.1370120628

Source DB:  PubMed          Journal:  Genet Epidemiol        ISSN： 0741-0395            Impact factor:   2.135


  9 in total

1.  Joint multipoint linkage analysis of multivariate qualitative and quantitative traits. I. Likelihood formulation and simulation results.

Authors:  J T Williams; P Van Eerdewegh; L Almasy; J Blangero
Journal:  Am J Hum Genet       Date:  1999-10       Impact factor: 11.025

2.  Computationally efficient multipoint linkage analysis on extended pedigrees for trait models with two contributing major Loci.

Authors:  Ming Su; Elizabeth A Thompson
Journal:  Genet Epidemiol       Date:  2012-06-27       Impact factor: 2.135

3.  Affecteds-only linkage methods are not a panacea.

Authors:  D A Greenberg; S E Hodge; V J Vieland; M A Spence
Journal:  Am J Hum Genet       Date:  1996-04       Impact factor: 11.025

4.  Markov chain Monte Carlo segregation and linkage analysis for oligogenic models.

Authors:  S C Heath
Journal:  Am J Hum Genet       Date:  1997-09       Impact factor: 11.025

5.  1996 William Allan Award Address. Algorithms and inferences: the challenge of multifactorial diseases.

Authors:  R C Elston
Journal:  Am J Hum Genet       Date:  1997-02       Impact factor: 11.025

6.  Genomewide scan for real-word reading subphenotypes of dyslexia: novel chromosome 13 locus and genetic complexity.

Authors:  Robert P Igo; Nicola H Chapman; Virginia W Berninger; Mark Matsushita; Zoran Brkanac; Joseph H Rothstein; Ted Holzman; Kathleen Nielsen; Wendy H Raskind; Ellen M Wijsman
Journal:  Am J Med Genet B Neuropsychiatr Genet       Date:  2006-01-05       Impact factor: 3.568

7.  Quantitative variation in obesity-related traits and insulin precursors linked to the OB gene region on human chromosome 7.

Authors:  R Duggirala; M P Stern; B D Mitchell; L J Reinhart; P A Shipman; O C Uresandi; W K Chung; R L Leibel; C N Hales; P O'Connell; J Blangero
Journal:  Am J Hum Genet       Date:  1996-09       Impact factor: 11.025

8.  Bivariate genome-wide scan for metabolic phenotypes in non-diabetic Chinese individuals from the Stanford, Asia and Pacific Program of Hypertension and Insulin Resistance Family Study.

Authors:  Y-F Chiu; L-M Chuang; H-Y Kao; L-T Ho; C-T Ting; Y-J Hung; Y-D Chen; T Donlon; J D Curb; T Quertermous; C A Hsiung
Journal:  Diabetologia       Date:  2007-06-20       Impact factor: 10.122

9.  ITGB5 and AGFG1 variants are associated with severity of airway responsiveness.

Authors:  Blanca E Himes; Weiliang Qiu; Barbara Klanderman; John Ziniti; Jody Senter-Sylvia; Stanley J Szefler; Robert F Lemanske; Robert S Zeiger; Robert C Strunk; Fernando D Martinez; Homer Boushey; Vernon M Chinchilli; Elliot Israel; David Mauger; Gerard H Koppelman; Maartje A E Nieuwenhuis; Dirkje S Postma; Judith M Vonk; Nicholas Rafaels; Nadia N Hansel; Kathleen Barnes; Benjamin Raby; Kelan G Tantisira; Scott T Weiss
Journal:  BMC Med Genet       Date:  2013-08-28       Impact factor: 2.103
  9 in total

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