Literature DB >> 8642550

3-((4-(4-Chlorophenyl)piperazin-1-yl)-methyl)-1H-pyrrolo-2,3-b-pyridine: an antagonist with high affinity and selectivity for the human dopamine D4 receptor.

J J Kulagowski1, H B Broughton, N R Curtis, I M Mawer, M P Ridgill, R Baker, F Emms, S B Freedman, R Marwood, S Patel, S Patel, C I Ragan, P D Leeson.   

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Year:  1996        PMID： 8642550     DOI： 10.1021/jm9600712

Source DB:  PubMed          Journal:  J Med Chem        ISSN： 0022-2623            Impact factor:   7.446


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  44 in total

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Authors:  Jianyong Chen; Gregory T Collins; Beth Levant; James Woods; Jeffrey R Deschamps; Shaomeng Wang
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Review 2.  The dopamine D4 receptor: biochemical and signalling properties.

Authors:  Pieter Rondou; Guy Haegeman; Kathleen Van Craenenbroeck
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3.  Striatal and extrastriatal microPET imaging of D2/D3 dopamine receptors in rat brain with [¹⁸F]fallypride and [¹⁸F]desmethoxyfallypride.

Authors:  Cristian C Constantinescu; Robert A Coleman; Min-Liang Pan; Jogeshwar Mukherjee
Journal:  Synapse       Date:  2011-03-21       Impact factor: 2.562

4.  Analogues of the dopamine D2 receptor antagonist L741,626: Binding, function, and SAR.

Authors:  Peter Grundt; Sarah Little Jane Husband; Robert R Luedtke; Michelle Taylor; Amy Hauck Newman
Journal:  Bioorg Med Chem Lett       Date:  2006-10-28       Impact factor: 2.823

5.  Exploring structure-selectivity relationships of biogenic amine GPCR antagonists using similarity searching and dynamic compound mapping.

Authors:  Ingo Vogt; Hany E A Ahmed; Jens Auer; Jürgen Bajorath
Journal:  Mol Divers       Date:  2008-03-04       Impact factor: 2.943

6.  A general, enantioselective synthesis of protected morpholines and piperazines.

Authors:  Matthew C O'Reilly; Craig W Lindsley
Journal:  Org Lett       Date:  2012-05-22       Impact factor: 6.005

7.  D2 dopamine receptor subtype-mediated hyperactivity and amphetamine responses in a model of ADHD.

Authors:  Xueliang Fan; Ming Xu; Ellen J Hess
Journal:  Neurobiol Dis       Date:  2009-10-22       Impact factor: 5.996

8.  Targeting Dopamine D2, Adenosine A2A, and Glutamate mGlu5 Receptors to Reduce Repetitive Behaviors in Deer Mice.

Authors:  Mark H Lewis; Christopher T Primiani; Amber M Muehlmann
Journal:  J Pharmacol Exp Ther       Date:  2019-02-11       Impact factor: 4.030

9.  Clozapine and olanzapine, but not haloperidol, reverse cold-induced and lipopolysaccharide-induced cutaneous vasoconstriction.

Authors:  William Walter Blessing
Journal:  Psychopharmacology (Berl)       Date:  2004-10       Impact factor: 4.530

10.  Identification of a new selective dopamine D4 receptor ligand.

Authors:  Dinithia Sampson; Xue Y Zhu; Suresh V K Eyunni; Jagan R Etukala; Edward Ofori; Barbara Bricker; Nazarius S Lamango; Vincent Setola; Bryan L Roth; Seth Y Ablordeppey
Journal:  Bioorg Med Chem       Date:  2014-04-20       Impact factor: 3.641
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