Literature DB >> 8611782

Asymptomatic gonorrhoea and chlamydial infection in rural Tanzanian men.

H Grosskurth1, P Mayaud, F Mosha, J Todd, K Senkoro, J Newell, R Gabone, J Changalucha, B West, R Hayes.   

Abstract

OBJECTIVE: To measure the prevalence of urethritis due to Neisseria gonorrhoeae and Chlamydial infection trachomatis in rural Tanzanian men
DESIGN: About 500 men aged 15-54 years were selected from each of 12 rural communities by random cluster sampling; interviewed concerning past or present symptoms of sexually transmitted diseases; and asked to provide a first catch urine specimen, which was tested for pyuria with a leucocyte esterase dipstick test. Subjects with symptoms or with a positive result on testing were examined, and urethral swabs were taken for detection of N gonorrhoeae by gram stain and of C trachomatis by antigen detection immunoassay.
SETTING: Mwanza region, north western Tanzania.
SUBJECTS: 5876 men aged 15-54 years. MAIN OUTCOME MEASURES: Prevalence of urethral symptoms, observed urethral discharge, pyuria, urethritis ( > 4 pus cells per high power field on urethral smear), N gonorrhoeae infection (intracellular gram negative diplococci), and C trachomatis infection (IDEIA antigen detection assay).
RESULTS: 1618 (28%) subjects reported ever having a urethral discharge. Current discharge was reported by 149 (2.5%) and observed on examination in 207 (3.5%). Gonorrhoea was found in 128 subjects (2.2%) and chlamydial infection in 39 (0.7%). Only 24 of 158 infected subjects complained of urethral discharge at the time of interview (15%).
CONCLUSION: Infection with N gonorrhoeae and C trachomatis is commonly asymptomatic among men in this rural African population. This has important implications for the design of control programmes for sexually transmitted disease.

Entities:  

Keywords:  Africa; Africa South Of The Sahara; Biology; Chlamydia--men; Demographic Factors; Developing Countries; Diseases; Eastern Africa; English Speaking Africa; Examinations And Diagnoses; Gonorrhea--men; Infections; Laboratory Examinations And Diagnoses; Laboratory Procedures; Measurement; Physiology; Population; Population Characteristics; Prevalence; Reproductive Tract Infections; Research Methodology; Rural Population--men; Sexually Transmitted Diseases; Signs And Symptoms; Tanzania; Urogenital Effects; Urogenital System

Mesh:

Year:  1996        PMID: 8611782      PMCID: PMC2349889          DOI: 10.1136/bmj.312.7026.277

Source DB:  PubMed          Journal:  BMJ        ISSN: 0959-8138


  15 in total

1.  Urinary leukocyte esterase test: a screening method for the detection of asymptomatic chlamydial and gonococcal infections in men.

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5.  Unsuspected Chlamydia trachomatis infection in heterosexual men attending a sexually transmitted diseases clinic: evaluation of risk factors and screening methods.

Authors:  C A Rietmeijer; F N Judson; M B Van Hensbroek; J M Ehret; J M Douglas
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6.  Epidemiology and aetiology of urethritis in Swaziland.

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7.  Pregnancy loss, infant death, and suffering: legacy of syphilis and gonorrhoea in Africa.

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10.  The value of urine specimens in screening for male urethritis and its microbial aetiologies in Tanzania.

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8.  High prevalence of trichomoniasis in rural men in Mwanza, Tanzania: results from a population based study.

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9.  Sexually transmitted infections in male clients of female sex workers in Benin: risk factors and reassessment of the leucocyte esterase dipstick for screening of urethral infections.

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10.  Comparison of STD prevalences in the Mwanza, Rakai, and Masaka trial populations: the role of selection bias and diagnostic errors.

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