OBJECTIVES: The aim of this study was to determine the content and amount of residual monomer released from heat-cured and chemical-cured polymethyl methacrylate (PMMA) during storage in water. METHODS: Residual monomer was extracted from ground PMMA with tetrahydrofuran and from the storage water with n-hexane. Samples were analyzed by using HPLC-chromatography. Duration of the storage period in water was up to 8 wk at temperatures of +22 degrees C and +37 degrees C. RESULTS: Residual monomer content of chemical-cured PMMA was higher than that of heat-cured PMMA. The effect of storage temperature was significant (p<0.001). During the first day of storage at +37 degrees C, the monomer release from chemical-cured PMMA was 1906.7 ppm and from the heat-cured PMMA 34.5 ppm and that release was higher at +37 degrees C than at +22 degrees C (p<0.001). SIGNIFICANCE: This study suggests that the amount of released monomer can be diminished by storing the PMMA product in water for at least 1 d before use, preferably at +37 degrees C.
OBJECTIVES: The aim of this study was to determine the content and amount of residual monomer released from heat-cured and chemical-cured polymethyl methacrylate (PMMA) during storage in water. METHODS: Residual monomer was extracted from ground PMMA with tetrahydrofuran and from the storage water with n-hexane. Samples were analyzed by using HPLC-chromatography. Duration of the storage period in water was up to 8 wk at temperatures of +22 degrees C and +37 degrees C. RESULTS: Residual monomer content of chemical-cured PMMA was higher than that of heat-cured PMMA. The effect of storage temperature was significant (p<0.001). During the first day of storage at +37 degrees C, the monomer release from chemical-cured PMMA was 1906.7 ppm and from the heat-cured PMMA 34.5 ppm and that release was higher at +37 degrees C than at +22 degrees C (p<0.001). SIGNIFICANCE: This study suggests that the amount of released monomer can be diminished by storing the PMMA product in water for at least 1 d before use, preferably at +37 degrees C.
Authors: Shi-Qiang Gong; D Jeevanie Epasinghe; Bin Zhou; Li-Na Niu; Kirk A Kimmerling; Frederick A Rueggeberg; Cynthia K Y Yiu; Jing Mao; David H Pashley; Franklin R Tay Journal: Acta Biomater Date: 2013-02-26 Impact factor: 8.947
Authors: Matti J Peltola; Pekka K Vallittu; Ville Vuorinen; Allan A J Aho; Antti Puntala; Kalle M J Aitasalo Journal: Eur Arch Otorhinolaryngol Date: 2011-06-01 Impact factor: 2.503