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Literature DB >> 8109321

The role of the adenomatous polyposis coli (APC) gene in human cancers.

Y Nakamura¹.

Abstract

Entities: Disease Gene Species

Mesh：

Year: 1993 PMID： 8109321 DOI： 10.1016/s0065-230x(08)60315-2

Source DB: PubMed Journal: Adv Cancer Res ISSN： 0065-230X Impact factor: 6.242

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16 in total

Review 1. Molecular mechanism of adenomatous polyposis coli-induced blockade of base excision repair pathway in colorectal carcinogenesis.

Authors: Satya Narayan; Ritika Sharma
Journal: Life Sci Date: 2015-09-01 Impact factor: 5.037

2. Investigational Strategies for Detection and Intervention in Early-Stage Pancreatic Cancer. April 24-27, Annapolis, Maryland. Abstracts.

Authors:
Journal: Int J Pancreatol Date: 1994 Oct-Dec

3. Combined molecular and clinical approaches for the identification of families with familial adenomatous polyposis coli.

Authors: J F Gebert; C Dupon; M Kadmon; M Hahn; C Herfarth; M von Knebel Doeberitz; H K Schackert
Journal: Ann Surg Date: 1999-03 Impact factor: 12.969

4. Regulation of intracellular beta-catenin levels by the adenomatous polyposis coli (APC) tumor-suppressor protein.

Authors: S Munemitsu; I Albert; B Souza; B Rubinfeld; P Polakis
Journal: Proc Natl Acad Sci U S A Date: 1995-03-28 Impact factor: 11.205

5. Alterations in K-ras, APC and p53-multiple genetic pathway in colorectal cancer among Indians.

Authors: Pooja Malhotra; Mumtaz Anwar; Neha Nanda; Rakesh Kochhar; Jai Dev Wig; Kim Vaiphei; Safrun Mahmood
Journal: Tumour Biol Date: 2013-03-24

6. Influence of age on adenomatous polyposis coli and p53 mutation frequency in sporadic colorectal cancer-rarity of co-occurrence of mutations in APC, K-ras, and p53 genes.

Authors: Jy-Ming Chiang; Yah-Huei Wu Chou; Shih-Chieh Ma; Jim-Ray Chen
Journal: Virchows Arch Date: 2004-09-24 Impact factor: 4.064

The role of the adenomatous polyposis coli (APC) gene in human cancers.

Review 1. Molecular mechanism of adenomatous polyposis coli-induced blockade of base excision repair pathway in colorectal carcinogenesis.

2. Investigational Strategies for Detection and Intervention in Early-Stage Pancreatic Cancer. April 24-27, Annapolis, Maryland. Abstracts.

3. Combined molecular and clinical approaches for the identification of families with familial adenomatous polyposis coli.

4. Regulation of intracellular beta-catenin levels by the adenomatous polyposis coli (APC) tumor-suppressor protein.

5. Alterations in K-ras, APC and p53-multiple genetic pathway in colorectal cancer among Indians.

6. Influence of age on adenomatous polyposis coli and p53 mutation frequency in sporadic colorectal cancer-rarity of co-occurrence of mutations in APC, K-ras, and p53 genes.

7. Mutations in APC, Kirsten-ras, and p53--alternative genetic pathways to colorectal cancer.

8. APC2 plays an essential role in axonal projections through the regulation of microtubule stability.

9. APC gene: database of germline and somatic mutations in human tumors and cell lines.

10. A modifying locus for familial adenomatous polyposis may be present on chromosome 1p35-p36.