| Literature DB >> 858010 |
A H Drummond, D E MacIntyre, H J Olverman.
Abstract
Aspirin at therapeutic concentrations does not inhibit the uptake of 5-hydroxytryptamine (5-HT) by blood platelets nor induce release of 5-HT from platelets, although platelet aggregation responses to collagen and arachidonic acid (which are dependent on platelet prostaglandin synthesis) are abolished. This does not support an earlier claim that aspirin's effects on platelet function include inhibition of 5-HT transport.Entities:
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Year: 1977 PMID： 858010 PMCID： PMC1667754 DOI： 10.1111/j.1476-5381.1977.tb07735.x
Source DB: PubMed Journal: Br J Pharmacol ISSN： 0007-1188 Impact factor: 8.739