Literature DB >> 8570623

Channel behavior in a gamma-aminobutyrate transporter.

J N Cammack1, E A Schwartz.   

Abstract

Current produced by a gamma-aminobutyrate (GABA) transporter stably transfected into a mammalian cell line was observed in cell-attached and excised membrane patches. When GABA was absent, a fraction of the transporters produced cation-permeable channels. When GABA plus Na+ was on either side of the membrane, the majority of transporters produced a high-frequency current noise attributed to the movement of ions in an occluded pore.

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Year:  1996        PMID： 8570623      PMCID： PMC40121          DOI： 10.1073/pnas.93.2.723

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  15 in total

1.  A GABA transporter operates asymmetrically and with variable stoichiometry.

Authors:  J N Cammack; S V Rakhilin; E A Schwartz
Journal:  Neuron       Date:  1994-10       Impact factor: 17.173

2.  Relaxation and fluctuations of membrane currents that flow through drug-operated channels.

Authors:  D Colquhoun; A G Hawkes
Journal:  Proc R Soc Lond B Biol Sci       Date:  1977-11-14

Review 3.  Kinetic properties of ion carriers and channels.

Authors:  P Läuger
Journal:  J Membr Biol       Date:  1980-12-30       Impact factor: 1.843

4.  Ions required for the electrogenic transport of GABA by horizontal cells of the catfish retina.

Authors:  J N Cammack; E A Schwartz
Journal:  J Physiol       Date:  1993-12       Impact factor: 5.182

5.  Channel-like function of the Na,K pump probed at microsecond resolution in giant membrane patches.

Authors:  D W Hilgemann
Journal:  Science       Date:  1994-03-11       Impact factor: 47.728

6.  The variance of sodium current fluctuations at the node of Ranvier.

Authors:  F J Sigworth
Journal:  J Physiol       Date:  1980-10       Impact factor: 5.182

7.  Conducting states of a mammalian serotonin transporter.

Authors:  S Mager; C Min; D J Henry; C Chavkin; B J Hoffman; N Davidson; H A Lester
Journal:  Neuron       Date:  1994-04       Impact factor: 17.173

8.  Characterization of the glutamate transporter in retinal cones of the tiger salamander.

Authors:  S Eliasof; F Werblin
Journal:  J Neurosci       Date:  1993-01       Impact factor: 6.167

9.  Coupling of CFTR Cl- channel gating to an ATP hydrolysis cycle.

Authors:  T Baukrowitz; T C Hwang; A C Nairn; D C Gadsby
Journal:  Neuron       Date:  1994-03       Impact factor: 17.173

10.  Steady states, charge movements, and rates for a cloned GABA transporter expressed in Xenopus oocytes.

Authors:  S Mager; J Naeve; M Quick; C Labarca; N Davidson; H A Lester
Journal:  Neuron       Date:  1993-02       Impact factor: 17.173
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  39 in total

Review 1.  Proteins for transport of water and mineral nutrients across the membranes of plant cells.

Authors:  M J Chrispeels; N M Crawford; J I Schroeder
Journal:  Plant Cell       Date:  1999-04       Impact factor: 11.277

2.  Drosophila serotonin transporters have voltage-dependent uptake coupled to a serotonin-gated ion channel.

Authors:  A Galli; C I Petersen; M deBlaquiere; R D Blakely; L J DeFelice
Journal:  J Neurosci       Date:  1997-05-15       Impact factor: 6.167

Review 3.  Pharmacological and biochemical aspects of GABAergic neurotransmission: pathological and neuropsychobiological relationships.

Authors:  Renê Oliveira Beleboni; Ruither Oliveira Gomes Carolino; Andrea Baldocchi Pizzo; Lissandra Castellan-Baldan; Joaquim Coutinho-Netto; Wagner Ferreira dos Santos; Norberto Cysne Coimbra
Journal:  Cell Mol Neurobiol       Date:  2004-12       Impact factor: 5.046

4.  Patch-clamp and amperometric recordings from norepinephrine transporters: channel activity and voltage-dependent uptake.

Authors:  A Galli; R D Blakely; L J DeFelice
Journal:  Proc Natl Acad Sci U S A       Date:  1998-10-27       Impact factor: 11.205

Review 5.  Neurotransmitter transport: models in flux.

Authors:  M P Kavanaugh
Journal:  Proc Natl Acad Sci U S A       Date:  1998-10-27       Impact factor: 11.205

Review 6.  Bioenergetics of neurotransmitter transport.

Authors:  G Rudnick
Journal:  J Bioenerg Biomembr       Date:  1998-04       Impact factor: 2.945

7.  Ion binding and permeation at the GABA transporter GAT1.

Authors:  S Mager; N Kleinberger-Doron; G I Keshet; N Davidson; B I Kanner; H A Lester
Journal:  J Neurosci       Date:  1996-09-01       Impact factor: 6.167

8.  Single-channel currents produced by the serotonin transporter and analysis of a mutation affecting ion permeation.

Authors:  F Lin; H A Lester; S Mager
Journal:  Biophys J       Date:  1996-12       Impact factor: 4.033

9.  Potentiation of GABAA receptor activity by volatile anaesthetics is reduced by α5GABAA receptor-preferring inverse agonists.

Authors:  I Lecker; Y Yin; D S Wang; B A Orser
Journal:  Br J Anaesth       Date:  2013-03-27       Impact factor: 9.166

10.  Unitary cardiac Na+, Ca2+ exchange current magnitudes determined from channel-like noise and charge movements of ion transport.

Authors:  D W Hilgemann
Journal:  Biophys J       Date:  1996-08       Impact factor: 4.033
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