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Literature DB >> 856945

Sensitivity of macrophages from different species to African swine fever (ASF) virus.

Abstract

The swine white blood cells sensitive to African swine fever (ASF) virus are monocytes differentiated in vitro to macrophages. These cells have been characterized by their morphology, phagocytic capacity and the presence of receptors for swine immunoglobulin G in their membranes. ASF virus does not produce any detectable effect on macrophages from humans, rabbits, guinea pigs, hamsters or rats, whereas ASF virus-infected chicken macrophages show an enhancement of cellular DNA synthesis and an intense cytopathic effect. ASF virus, adapted to grow in VERO cells, produces a strong cytopathic effect in human macrophages leading to cell destruction. This effect is not associated with the synthesis of infectious virus, cellular or virus DNA nor with the formation of detectable virus-related structures.

Entities: Disease Species

Mesh：

Substances：
Immunoglobulin G
DNA

Year: 1977 PMID： 856945 DOI： 10.1099/0022-1317-34-3-455

Source DB: PubMed Journal: J Gen Virol ISSN： 0022-1317 Impact factor: 3.891

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Cited

16 in total

1. Identification of an African swine fever virus gene with similarity to a myeloid differentiation primary response gene and a neurovirulence-associated gene of herpes simplex virus.

Authors: M D Sussman; Z Lu; G Kutish; C L Afonso; P Roberts; D L Rock
Journal: J Virol Date: 1992-09 Impact factor: 5.103

2. Modulation of the structure, catalytic activity, and fidelity of African swine fever virus DNA polymerase X by a reversible disulfide switch.

Authors: Markus W Voehler; Robert L Eoff; W Hayes McDonald; F Peter Guengerich; Michael P Stone
Journal: J Biol Chem Date: 2009-05-05 Impact factor: 5.157

3. An African swine fever virus Bc1-2 homolog, 5-HL, suppresses apoptotic cell death.

Authors: C L Afonso; J G Neilan; G F Kutish; D L Rock
Journal: J Virol Date: 1996-07 Impact factor: 5.103

Review 4. Role of macrophages in natural resistance to virus infections.

Authors: S C Mogensen
Journal: Microbiol Rev Date: 1979-03

5. ASFV DNA polymerse X is extremely error-prone under diverse assay conditions and within multiple DNA sequence contexts.

Authors: Brandon J Lamarche; Sandeep Kumar; Ming-Daw Tsai
Journal: Biochemistry Date: 2006-12-12 Impact factor: 3.162

10. The low-virulent African swine fever virus (ASFV/NH/P68) induces enhanced expression and production of relevant regulatory cytokines (IFNalpha, TNFalpha and IL12p40) on porcine macrophages in comparison to the highly virulent ASFV/L60.

Authors: S Gil; N Sepúlveda; E Albina; A Leitão; C Martins
Journal: Arch Virol Date: 2008-09-12 Impact factor: 2.574

Sensitivity of macrophages from different species to African swine fever (ASF) virus.

1. Identification of an African swine fever virus gene with similarity to a myeloid differentiation primary response gene and a neurovirulence-associated gene of herpes simplex virus.

2. Modulation of the structure, catalytic activity, and fidelity of African swine fever virus DNA polymerase X by a reversible disulfide switch.

3. An African swine fever virus Bc1-2 homolog, 5-HL, suppresses apoptotic cell death.

Review 4. Role of macrophages in natural resistance to virus infections.

5. ASFV DNA polymerse X is extremely error-prone under diverse assay conditions and within multiple DNA sequence contexts.

Review 6. African Swine Fever virus. Brief review.

7. Porcine leukocyte cellular subsets sensitive to African swine fever virus in vitro.

8. The replication of virulent and attenuated strains of African swine fever virus in porcine macrophages.

9. Persistent in vitro interaction of virulent and attenuated canine distemper virus with bovine cells.

10. The low-virulent African swine fever virus (ASFV/NH/P68) induces enhanced expression and production of relevant regulatory cytokines (IFNalpha, TNFalpha and IL12p40) on porcine macrophages in comparison to the highly virulent ASFV/L60.