Literature DB >> 8564903

Access to adult liver transplantation in Canada: a survey and ethical analysis.

M A Mullen1, N Kohut, M Sam, L Blendis, P A Singer.   

Abstract

OBJECTIVES: To describe the substantive and procedural criteria used for placing patients on the waiting list for liver transplantation and for allocating available livers to patients on the waiting list; to identify principal decision-makers and the main factors limiting liver transplantation in Canada; and to examine how closely cadaveric liver allocation resembles theoretic models of source allocation.
DESIGN: Mailed survey. PARTICIPANTS: Medical directors of all seven Canadian adult liver transplantation centres, or their designates. Six of the questionnaires were completed. OUTCOME MEASURES: Relative importance of substantive and procedural criteria used to place patients in the waiting list for liver transplantation and to allocate available livers. Identification of principal decision-makers and main limiting factors to adult liver transplantation.
RESULTS: Alcoholism, drug addiction, HIV positivity, primary liver cancer, noncompliance and hepatitis B were the most important criteria that had a negative influence on decisions to place patients on the waiting list for liver transplantation. Severity of disease and urgency were the most important criteria used for selecting patients on the waiting list for transplantation. Criteria that were inconsistent across the centres included social support (for deciding who is placed on the waiting list) and length of time on the waiting list (for deciding who is selected from the list). Although a variety of people were reported as being involved in these decisions, virtually all were reported to be health to be health care professionals. Thirty-seven patients died while waiting for liver transplantation in 1991; the scarcity of cadaveric livers was the main limiting factor.
CONCLUSIONS: Criteria for resource allocation decisions regarding liver transplantation are generally consistent among the centres across Canada, although some important inconsistencies remain. Because patients die while on the waiting list and because the primary limiting factor is organ supply, increased organ acquisition efforts are needed.

Entities:  

Keywords:  Empirical Approach; Health Care and Public Health; United Network for Organ Sharing

Mesh:

Year:  1996        PMID: 8564903      PMCID: PMC1487520     

Source DB:  PubMed          Journal:  CMAJ        ISSN: 0820-3946            Impact factor:   8.262


  4 in total

1.  The shortage of organs for transplantation. Where do we go from here?

Authors:  A Spital
Journal:  N Engl J Med       Date:  1991-10-24       Impact factor: 91.245

2.  Psychosocial evaluation of organ transplant candidates. A comparative survey of process, criteria, and outcomes in heart, liver, and kidney transplantation.

Authors:  J L Levenson; M E Olbrisch
Journal:  Psychosomatics       Date:  1993 Jul-Aug       Impact factor: 2.386

3.  Liver transplantation in patients with alcoholic cirrhosis: selection criteria and rates of survival and relapse.

Authors:  G L Bird; J G O'Grady; F A Harvey; R Y Calne; R Williams
Journal:  BMJ       Date:  1990-07-07

Review 4.  A review of public policies to procure and distribute kidneys for transplantation.

Authors:  P A Singer
Journal:  Arch Intern Med       Date:  1990-03
  4 in total
  8 in total

1.  Access to pediatric liver transplantation: does regional variation play a role?

Authors:  Mary T Austin; Irene D Feurer; C Wright Pinson
Journal:  J Gastrointest Surg       Date:  2006-03       Impact factor: 3.452

Review 2.  Bioethics for clinicians: 13. Resource allocation.

Authors:  M F McKneally; B M Dickens; E M Meslin; P A Singer
Journal:  CMAJ       Date:  1997-07-15       Impact factor: 8.262

3.  Liver transplantation in HCV/HIV positive patients.

Authors:  Yasuhiko Sugawara; Sumihito Tamura; Norihiro Kokudo
Journal:  World J Gastrointest Surg       Date:  2011-02-27

Review 4.  Pros and cons of liver transplantation in human immunodeficiency virus infected recipients.

Authors:  Umberto Baccarani; Elda Righi; Gian Luigi Adani; Dario Lorenzin; Alberto Pasqualucci; Matteo Bassetti; Andrea Risaliti
Journal:  World J Gastroenterol       Date:  2014-05-14       Impact factor: 5.742

5.  Assessing priorities for allocation of donor liver grafts: survey of public and clinicians.

Authors:  J Neuberger; D Adams; P MacMaster; A Maidment; M Speed
Journal:  BMJ       Date:  1998-07-18

6.  Organ allocation for liver transplantation according to the public opinion.

Authors:  Ahmad Danesh; Saharnaz Nedjat; Fariba Asghari; Ali Jafarian; Akbar Fotouhi
Journal:  Hepat Mon       Date:  2012-08-20       Impact factor: 0.660

7.  HIV and liver transplantation: The British Columbia experience, 2004 to 2013.

Authors:  Clara Tan-Tam; Pamela Liao; Julio S Montaner; Mark W Hull; Charles H Scudamore; Siegfried R Erb; Eric M Yoshida
Journal:  Can J Infect Dis Med Microbiol       Date:  2014-05       Impact factor: 2.471

8.  Liver transplantation in the critically ill: a multicenter Canadian retrospective cohort study.

Authors:  Constantine J Karvellas; Thomas Lescot; Peter Goldberg; Michael D Sharpe; Juan J Ronco; Eberhard L Renner; Hina Vahidy; Zafrina Poonja; Prosanto Chaudhury; Norman M Kneteman; Markus Selzner; Earl F Cook; Sean M Bagshaw
Journal:  Crit Care       Date:  2013-02-09       Impact factor: 9.097

  8 in total

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