Literature DB >> 9665895

Assessing priorities for allocation of donor liver grafts: survey of public and clinicians.

J Neuberger1, D Adams, P MacMaster, A Maidment, M Speed.   

Abstract

OBJECTIVES: To compare the priorities of the general public, family doctors, and gastroenterologists in allocating donor livers to potential recipients of liver allograft.
DESIGN: Representative quota sampling of 1000 members of the general public and 200 family doctors, and a postal questionnaire of 100 gastroenterologists.
SUBJECTS: Respondents were given eight hypothetical case histories (based on real patients) and asked to select recipients for four donor livers. Cases were selected to identify controversial areas such as extremes of age, misuse of alcohol, and intravenous drugs. Respondents were also asked to select the least deserving case and which of seven possible factors (time on waiting list, outcome, age, value to society, return to work, previous use of illicit drugs, and involvement of alcohol in the liver damage) should be used to select patients already listed for transplantation. Focus groups were also held to explore further the reasons for the choices given.
RESULTS: There were considerable differences between the three groups in the choice of the recipients, although alcohol use and antisocial behaviour always rated low. For selection of recipients the general public thought that, in decreasing order of importance, age, outcome, and time on the waiting list were the most important factors in selecting recipients; family doctors rated outcome, age, and likely work status after transplantation and the gastroenterologists outcome, work status, and non-involvement of alcohol in the cause of the liver disease as the most important factors.
CONCLUSIONS: The views of the public are at variance with those of clinicians. Further debate is required to ensure an equitable and appropriate distribution of a scarce resource.

Entities:  

Keywords:  Empirical Approach; Health Care and Public Health

Mesh:

Year:  1998        PMID: 9665895      PMCID: PMC28607          DOI: 10.1136/bmj.317.7152.172

Source DB:  PubMed          Journal:  BMJ        ISSN: 0959-8138


  20 in total

1.  Defending tough decisions in a case open to hindsight.

Authors:  Lawrence K Altman
Journal:  N Y Times Web       Date:  1995-08-15

2.  Transplantation in alcoholics: separating prognosis and responsibility from social biases.

Authors:  P A Ubel
Journal:  Liver Transpl Surg       Date:  1997-05

3.  Guiding principles on human organ transplantation. World Health Organization.

Authors: 
Journal:  Lancet       Date:  1991-06-15       Impact factor: 79.321

4.  Rationing health care: moving the debate forward.

Authors:  R Smith
Journal:  BMJ       Date:  1996-06-22

5.  Procurement and allocation of solid organs for transplantation.

Authors:  P J Hauptman; K J O'Connor
Journal:  N Engl J Med       Date:  1997-02-06       Impact factor: 91.245

6.  Disease gravity and urgency of need as guidelines for liver allocation.

Authors:  B Eghtesad; O Bronsther; W Irish; A Casavilla; K Abu-Elmagd; D Van Thiel; A Tzakis; J J Fung; T E Starzl
Journal:  Hepatology       Date:  1994-07       Impact factor: 17.425

Review 7.  Organ donors and nondonors. An American dilemma.

Authors:  T G Peters; D S Kittur; L J McGaw; E W Nelson
Journal:  Arch Intern Med       Date:  1996-11-25

Review 8.  Ethical considerations in the allocation of organs and other scarce medical resources among patients. Council on Ethical and Judicial Affairs, American Medical Association.

Authors: 
Journal:  Arch Intern Med       Date:  1995-01-09

9.  Public perceptions of the importance of prognosis in allocating transplantable livers to children.

Authors:  P A Ubel; G Loewenstein
Journal:  Med Decis Making       Date:  1996 Jul-Sep       Impact factor: 2.583

10.  Access to adult liver transplantation in Canada: a survey and ethical analysis.

Authors:  M A Mullen; N Kohut; M Sam; L Blendis; P A Singer
Journal:  CMAJ       Date:  1996-02-01       Impact factor: 8.262

View more
  44 in total

1.  Psychosocial factors in selection for liver transplantation. Need to be explicitly assessed and managed.

Authors:  G Masterton
Journal:  BMJ       Date:  2000-01-29

2.  Studies on avian erythrocyte metabolism--I. Procedure for separation and quantitation of the major phosphorylated metabolic intermediates by anion exchange chromatography.

Authors:  R E Isaacks; D R Harkness; G A Froeman; S A Sussman
Journal:  Comp Biochem Physiol A Comp Physiol       Date:  1976-01

Review 3.  Artificial and bioartificial support systems for liver failure.

Authors:  J P Liu; L L Gluud; B Als-Nielsen; C Gluud
Journal:  Cochrane Database Syst Rev       Date:  2004

4.  Liver transplantation in acute alcoholic hepatitis: Current status and future development.

Authors:  Ashwani K Singal; Andrea Duchini
Journal:  World J Hepatol       Date:  2011-08-27

5.  The psychiatric diagnosis of alcohol abuse and the medical diagnosis of alcoholic related liver disease: effects on liver transplant survival.

Authors:  Anthony A Rowley; Barry A Hong; William Chapman; Jeffrey S Crippin
Journal:  J Clin Psychol Med Settings       Date:  2010-09

6.  Futility and rationing in liver retransplantation: when and how can we say no?

Authors:  Scott W Biggins
Journal:  J Hepatol       Date:  2012-02-04       Impact factor: 25.083

7.  The impact of prognosis without treatment on doctors' and patients' resource allocation decisions and its relevance to new drug recommendation processes.

Authors:  D Ross Camidge; James J Oliver; Carolyn Skinner; Ben Attwood; Fiona Nussey; Duncan Jodrell; David J Webb
Journal:  Br J Clin Pharmacol       Date:  2008-02       Impact factor: 4.335

8.  Predictors of relapse to significant alcohol drinking after liver transplantation.

Authors:  Zamil Karim; Pongphob Intaraprasong; Charles H Scudamore; Siegfried R Erb; John G Soos; Elsie Cheung; Polly Cooper; Andrzej K Buzckowski; Stephen W Chung; Urs P Steinbrecher; Eric M Yoshida
Journal:  Can J Gastroenterol       Date:  2010-04       Impact factor: 3.522

9.  Societal reintegration after liver transplantation: findings in alcohol-related and non-alcohol-related transplant recipients.

Authors:  Terianne Cowling; Linda W Jennings; Robert M Goldstein; Edmund Q Sanchez; Srinath Chinnakotla; Goran B Klintmalm; Marlon F Levy
Journal:  Ann Surg       Date:  2004-01       Impact factor: 12.969

10.  Management of Alcohol Use Disorder in Patients Requiring Liver Transplant.

Authors:  Mary R Lee; Lorenzo Leggio
Journal:  Am J Psychiatry       Date:  2015-12       Impact factor: 18.112

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.