Literature DB >> 856016

Assay of gentamicin in serum by high-pressure liquid chromatography.

J P Anhalt.   

Abstract

A procedure is described that uses high-pressure liquid chromatography for assay of gentamicin in serum. The technique involves extraction of gentamicin from serum by using a CM-Sephadex column and analysis by reverse-phase, ion-pair chromatography. Continuous-flow, post-column derivatization with o-phthaladehyde is used to form fluorescent products for detection. The possible scope of this method for analysis of other aminoglycoside antibiotics is illustrated by application to sisomicin and netilmicin.

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Year:  1977        PMID： 856016      PMCID： PMC352044          DOI： 10.1128/AAC.11.4.651

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  9 in total

1.  Assay of flucytosine and furosemide by high-pressure liquid chromatography.

Authors:  A D Blair; A W Forrey; B T Meijsen; R E Cutler
Journal:  J Pharm Sci       Date:  1975-08       Impact factor: 3.534

2.  Separation of gentamicin complex by ion-exchange column chromatography.

Authors:  A H Thomas; S D Tappin
Journal:  J Chromatogr       Date:  1974-10-23

3.  Chemical determination of component ratio and potency of gentamicin complex.

Authors:  W L Wilson; G Richard; D W Hughes
Journal:  J Pharm Sci       Date:  1973-02       Impact factor: 3.534

4.  Fluorescence reaction for amino acids.

Authors:  M Roth
Journal:  Anal Chem       Date:  1971-06       Impact factor: 6.986

5.  Quantitation of antibiotics using high-pressure liquid chromatography: tetracycline.

Authors:  I Nilsson-Ehle; T T Yoshikawa; M C Schotz; L B Guze
Journal:  Antimicrob Agents Chemother       Date:  1976-05       Impact factor: 5.191

6.  Ion-pair extraction and high-speed liquid chromatography of cephalothin and deacetylcephalothin in human serum and urine.

Authors:  M J Cooper; M W Anders; B L Mirkin
Journal:  Drug Metab Dispos       Date:  1973 Sep-Oct       Impact factor: 3.922

7.  Reversed-phase ion-pair partition chromatography of carboxylates and sulphonates.

Authors:  K G Wahlung
Journal:  J Chromatogr       Date:  1975-12-24

8.  High-performance liquid chromatographic determination of kanamycin.

Authors:  D L Mays; R J Van Apeldoorn; R G Lauback
Journal:  J Chromatogr       Date:  1976-05-12

9.  O-phthalaldehyde: fluorogenic detection of primary amines in the picomole range. Comparison with fluorescamine and ninhydrin.

Authors:  J R Benson; P E Hare
Journal:  Proc Natl Acad Sci U S A       Date:  1975-02       Impact factor: 11.205
  9 in total
  13 in total

1.  Gentamicin-Loaded Polysaccharide Membranes for Prevention and Treatment of Post-operative Wound Infections in the Skeletal System.

Authors:  Urszula Cibor; Małgorzata Krok-Borkowicz; Monika Brzychczy-Włoch; Łucja Rumian; Krzysztof Pietryga; Dominika Kulig; Wojciech Chrzanowski; Elżbieta Pamuła
Journal:  Pharm Res       Date:  2017-06-21       Impact factor: 4.200

2.  High-pressure liquid chromatographic assay of netilmicin in plasma.

Authors:  G W Peng; G G Jackson; W L Chiou
Journal:  Antimicrob Agents Chemother       Date:  1977-12       Impact factor: 5.191

3.  Anion-exchange extraction of cephapirin, cefotaxime, and cefoxitin from serum for liquid chromatography.

Authors:  C E Fasching; L R Peterson
Journal:  Antimicrob Agents Chemother       Date:  1982-04       Impact factor: 5.191

4.  Comparison of different tobramycin assays.

Authors:  E E Stobberingh; A W Houben; C P van Boven
Journal:  J Clin Microbiol       Date:  1982-05       Impact factor: 5.948

5.  Comparison of enzyme-multiplied immunoassay technique with fluorescence polarization immunoassay for determination of gentamicin and tobramycin levels in serum.

Authors:  D J Pohlod; L D Saravolatz; M M Somerville
Journal:  J Clin Microbiol       Date:  1984-11       Impact factor: 5.948

6.  Rapid method for determination of kanamycin and dibekacin in serum by use of high-pressure liquid chromatography.

Authors:  H Kubo; Y Kobayashi; T Nishikawa
Journal:  Antimicrob Agents Chemother       Date:  1985-10       Impact factor: 5.191

7.  Radioimmunoassay of gentamicin in Micromonospora medium extracts.

Authors:  A Rosner; H Aviv
Journal:  Antimicrob Agents Chemother       Date:  1980-03       Impact factor: 5.191

8.  Determination of Gentamicin Sulphate Composition and Related Substances in Pharmaceutical Preparations by LC with Charged Aerosol Detection.

Authors:  Karolina Stypulkowska; Agata Blazewicz; Zbigniew Fijalek; Katarzyna Sarna
Journal:  Chromatographia       Date:  2010-10-01       Impact factor: 2.044

9.  Assay of gentamicin and tobramycin in sera of patients by gas-liquid chromatography.

Authors:  J W Mayhew; S L Gorbach
Journal:  Antimicrob Agents Chemother       Date:  1978-12       Impact factor: 5.191

10.  Amikacin assay in serum by high-performance liquid chromatography.

Authors:  S K Maitra; T T Yoshikawa; C M Steyn; L B Guze; M C Schotz
Journal:  Antimicrob Agents Chemother       Date:  1978-12       Impact factor: 5.191
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