Literature DB >> 8546330

Structure and function of podocytes: an update.

P Mundel1, W Kriz.   

Abstract

Glomerular visceral epithelial cells, also termed podocytes, are highly specialized epithelial cells that cover the outer aspect of the glomerular basement membrane. Recent studies point to an important role of podocytes in the physiology and pathophysiology of the glomerulus. This review summarizes the structure-function relationships of podocytes. Following a description of the general morphology of podocytes, the technical problems associated with studying these cells are discussed. A survey of podocyte function forms the center of this review. Finally, selected aspects of podocyte development and cell division are discussed.

Mesh：

Year:  1995        PMID： 8546330     DOI： 10.1007/bf00240371

Source DB:  PubMed          Journal:  Anat Embryol (Berl)        ISSN： 0340-2061


  119 in total

1.  Basement membrane heparan sulfate proteoglycan is the main proteoglycan synthesized by glomerular epithelial cells in culture.

Authors:  J L Stow; C J Soroka; K MacKay; L Striker; G Striker; M G Farquhar
Journal:  Am J Pathol       Date:  1989-10       Impact factor: 4.307

2.  Isolation and characterization of an unique kidney antigen of relevance in human renal disease.

Authors:  R Kittelberger; T J Neale
Journal:  Biochem Biophys Res Commun       Date:  1990-10-30       Impact factor: 3.575

3.  Glomerular hypertrophy and epithelial cell injury modulate progressive glomerulosclerosis in the rat.

Authors:  J W Fries; D J Sandstrom; T W Meyer; H G Rennke
Journal:  Lab Invest       Date:  1989-02       Impact factor: 5.662

4.  Localization of smooth muscle-like contractile proteins in kidney by immunoelectron microscopy.

Authors:  P Trenchev; J Dorling; J Webb; E J Holborow
Journal:  J Anat       Date:  1976-02       Impact factor: 2.610

5.  Pathogenesis of polycation-induced alterations ("fusion") of glomerular epithelium.

Authors:  M W Seiler; H G Rennke; M A Venkatachalam; R S Cotran
Journal:  Lab Invest       Date:  1977-01       Impact factor: 5.662

6.  Retraction of epithelial foot processes during culture of isolated glomeruli.

Authors:  J O Nörgaard
Journal:  Lab Invest       Date:  1978-03       Impact factor: 5.662

7.  Dual origin of glomerular basement membrane.

Authors:  H Sariola; R Timpl; K von der Mark; R Mayne; J M Fitch; T F Linsenmayer; P Ekblom
Journal:  Dev Biol       Date:  1984-01       Impact factor: 3.582

8.  Extracellular matrix regulates proliferation and phospholipid turnover in glomerular epithelial cells.

Authors:  A V Cybulsky; J V Bonventre; R J Quigg; L S Wolfe; D J Salant
Journal:  Am J Physiol       Date:  1990-08

9.  Characterization of C-type natriuretic peptide receptors in human mesangial cells.

Authors:  J Zhao; N Ardaillou; C Y Lu; S Placier; P Pham; L Badre; J Cambar; R Ardaillou
Journal:  Kidney Int       Date:  1994-09       Impact factor: 10.612

10.  Nuclear localization of the protein encoded by the Wilms' tumor gene WT1 in embryonic and adult tissues.

Authors:  S Mundlos; J Pelletier; A Darveau; M Bachmann; A Winterpacht; B Zabel
Journal:  Development       Date:  1993-12       Impact factor: 6.868
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  92 in total

1.  Co-localization of nephrin, podocin, and the actin cytoskeleton: evidence for a role in podocyte foot process formation.

Authors:  Moin A Saleem; Lan Ni; Ian Witherden; Karl Tryggvason; Vesa Ruotsalainen; Peter Mundel; Peter W Mathieson
Journal:  Am J Pathol       Date:  2002-10       Impact factor: 4.307

2.  Increased urinary podocytes following indomethacin suggests drug-induced glomerular injury.

Authors:  Alison L Kent; Linda Brown; Margaret Broom; Amy Broomfield; Jane E Dahlstrom
Journal:  Pediatr Nephrol       Date:  2012-03-14       Impact factor: 3.714

3.  Nef interaction with actin compromises human podocyte actin cytoskeletal integrity.

Authors:  Raymond Tan; Hitesh Patni; Pranai Tandon; Liming Luan; Bipin Sharma; Divya Salhan; Moin A Saleem; Peter W Mathieson; Ashwani Malhotra; Mohammad Husain; Poornima Upadhya; Pravin C Singhal
Journal:  Exp Mol Pathol       Date:  2012-06-18       Impact factor: 3.362

4.  Cyclic AMP prevents decrease of phosphorylated ezrin/radixin/moesin and chloride intracellular channel 5 expressions in injured podocytes.

Authors:  Hua Tao; Xiaoying Li; Kai Wei; Kewei Xie; Zhaohui Ni; Leyi Gu
Journal:  Clin Exp Nephrol       Date:  2015-03-01       Impact factor: 2.801

5.  Clathrin and clathrin-accessory proteins in rat kidney cortex epithelia.

Authors:  Sabine Hasse; Ernst J Ungewickell; Stephanie Groos
Journal:  Histochem Cell Biol       Date:  2006-04-20       Impact factor: 4.304

Review 6.  Signal transduction in podocytes--spotlight on receptor tyrosine kinases.

Authors:  Jochen Reiser; Sanja Sever; Christian Faul
Journal:  Nat Rev Nephrol       Date:  2014-01-07       Impact factor: 28.314

7.  Connective tissue growth factor modulates podocyte actin cytoskeleton and extracellular matrix synthesis and is induced in podocytes upon injury.

Authors:  Rudolf Fuchshofer; Sabrina Ullmann; Ludwig F Zeilbeck; Matti Baumann; Benjamin Junglas; Ernst R Tamm
Journal:  Histochem Cell Biol       Date:  2011-08-04       Impact factor: 4.304

8.  Urinary podocalyxin as a possible novel marker of intrauterine nephrogenesis and extrauterine podocyte injury.

Authors:  Taihei Hayashi; Shuko Tokuriki; Takashi Okuno; Genrei Ohta; Aiko Igarashi; Yusei Ohshima
Journal:  Pediatr Nephrol       Date:  2017-04-25       Impact factor: 3.714

9.  High-glucose and advanced glycosylation end products increased podocyte permeability via PI3-K/Akt signaling.

Authors:  Tae-Sun Ha
Journal:  J Mol Med (Berl)       Date:  2010-01-08       Impact factor: 4.599

10.  Association of phospholipase A2 receptor 1 polymorphisms with idiopathic membranous nephropathy in Chinese patients in Taiwan.

Authors:  Yu-Huei Liu; Cheng-Hsu Chen; Shih-Yin Chen; Ying-Ju Lin; Wen-Ling Liao; Chang-Hai Tsai; Lei Wan; Fuu-Jen Tsai
Journal:  J Biomed Sci       Date:  2010-10-11       Impact factor: 8.410
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