Literature DB >> 8535048

Osteoarthritis in older patients. Optimum treatment.

E Bagge1, P Brooks.   

Abstract

A number of therapeutic options to control pain, maintain function and decrease disability are available for older patients with osteoarthritis. The indication for pharmacological therapy should be restricted to periods with pain. Great attention should be given to nonpharmacological interventions such as education, exercise, lifestyle modification and emotional support. If medication is necessary, most patients require only pure analgesics such as paracetamol (acetaminophen); nonsteroidal anti-inflammatory drugs (NSAIDs) should be used if patients do not respond to simpler measures. All medication should be carefully monitored considering the frequency of adverse drug reactions in older patients.

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Year:  1995        PMID: 8535048     DOI: 10.2165/00002512-199507030-00003

Source DB:  PubMed          Journal:  Drugs Aging        ISSN: 1170-229X            Impact factor:   3.923


  41 in total

1.  Reduction of joint pain in patients with knee osteoarthritis who have received monthly telephone calls from lay personnel and whose medical treatment regimens have remained stable.

Authors:  J René; M Weinberger; S A Mazzuca; K D Brandt; B P Katz
Journal:  Arthritis Rheum       Date:  1992-05

2.  Walking habits and health-related factors in a 70-year-old population.

Authors:  K Frändin; G Grimby; D Mellström; A Svanborg
Journal:  Gerontology       Date:  1991       Impact factor: 5.140

3.  Comparison of an antiinflammatory dose of ibuprofen, an analgesic dose of ibuprofen, and acetaminophen in the treatment of patients with osteoarthritis of the knee.

Authors:  J D Bradley; K D Brandt; B P Katz; L A Kalasinski; S I Ryan
Journal:  N Engl J Med       Date:  1991-07-11       Impact factor: 91.245

Review 4.  Nonsteroidal anti-inflammatory drugs. Differential use in older patients.

Authors:  L Girgis; P Brooks
Journal:  Drugs Aging       Date:  1994-02       Impact factor: 3.923

5.  A two-year, placebo-controlled trial of non-steroidal anti-inflammatory therapy in osteoarthritis of the knee joint.

Authors:  P Dieppe; J Cushnaghan; M K Jasani; F McCrae; I Watt
Journal:  Br J Rheumatol       Date:  1993-07

6.  Risk of upper gastrointestinal bleeding and perforation associated with individual non-steroidal anti-inflammatory drugs.

Authors:  L A García Rodríguez; H Jick
Journal:  Lancet       Date:  1994-03-26       Impact factor: 79.321

7.  Osteo-arthrosis. Prevalence in the population and relationship between symptoms and x-ray changes.

Authors:  J S Lawrence; J M Bremner; F Bier
Journal:  Ann Rheum Dis       Date:  1966-01       Impact factor: 19.103

8.  High-intensity strength training in nonagenarians. Effects on skeletal muscle.

Authors:  M A Fiatarone; E C Marks; N D Ryan; C N Meredith; L A Lipsitz; W J Evans
Journal:  JAMA       Date:  1990-06-13       Impact factor: 56.272

9.  Additive effect of combined naproxen and paracetamol in rheumatoid arthritis.

Authors:  P Seideman
Journal:  Br J Rheumatol       Date:  1993-12

10.  Intra-articular steroids in osteoarthritis.

Authors:  P A Dieppe; B Sathapatayavongs; H E Jones; P A Bacon; E F Ring
Journal:  Rheumatol Rehabil       Date:  1980-11
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  2 in total

Review 1.  Oral versus topical NSAIDs in rheumatic diseases: a comparison.

Authors:  C A Heyneman; C Lawless-Liday; G C Wall
Journal:  Drugs       Date:  2000-09       Impact factor: 9.546

Review 2.  Diclofenac/misoprostol. A review of its pharmacology and therapeutic efficacy in painful inflammatory conditions.

Authors:  R Davis; Y E Yarker; K L Goa
Journal:  Drugs Aging       Date:  1995-11       Impact factor: 3.923

  2 in total

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