Literature DB >> 8523090

Growth inhibition of human glioma cells modulated by retrovirus gene transfection with antisense IL-8.

R Yamanaka1, R Tanaka, S Yoshida, T Saitoh, K Fujita.   

Abstract

The human glioma cell line, NP-1, expresses IL-8 mRNA and constitutively secretes IL-8 protein. Administration of recombinant IL-8 increased the proliferation of NP-1 cells in a dose-dependent manner. In the presence of anti-IL-8 antiserum, the IL-8 mediated proliferation of NP-1 cell growth was inhibited. Further, NP-1 cell growth was inhibited by transfection of retroviral constructs encoding antisense IL-8 both in vitro and in vivo models. These results suggest that antisense IL-8 gene therapy could be beneficial in gliomas where autocrine stimulation by IL-8 is implicated.

Entities:  

Mesh：

Substances：

Year:  1995        PMID： 8523090     DOI： 10.1007/bf01054723

Source DB:  PubMed          Journal:  J Neurooncol        ISSN： 0167-594X            Impact factor:   4.130


  24 in total

1.  Purification and partial biochemical characterization of a human monocyte-derived, neutrophil-activating peptide that lacks interleukin 1 activity.

Authors:  J M Schröder; U Mrowietz; E Morita; E Christophers
Journal:  J Immunol       Date:  1987-11-15       Impact factor: 5.422

2.  Expression of human class II major histocompatibility complex antigens using retrovirus vectors.

Authors:  A J Korman; J D Frantz; J L Strominger; R C Mulligan
Journal:  Proc Natl Acad Sci U S A       Date:  1987-04       Impact factor: 11.205

3.  Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose.

Authors:  P S Thomas
Journal:  Proc Natl Acad Sci U S A       Date:  1980-09       Impact factor: 11.205

4.  Expression of HLA-DR and common acute lymphoblastic leukemia antigens on glioma cells.

Authors:  S Carrel; N De Tribolet; N Gross
Journal:  Eur J Immunol       Date:  1982-04       Impact factor: 5.532

5.  Cytokine gene expression on glioma cell lines and specimens.

Authors:  R Yamanaka; R Tanaka; T Saitoh; S Okoshi
Journal:  J Neurooncol       Date:  1994       Impact factor: 4.130

6.  Retroviral-mediated gene therapy for the treatment of hepatocellular carcinoma: an innovative approach for cancer therapy.

Authors:  B E Huber; C A Richards; T A Krenitsky
Journal:  Proc Natl Acad Sci U S A       Date:  1991-09-15       Impact factor: 11.205

7.  Response of glioma cells to interferon-gamma: increase in class II RNA, protein and mixed lymphocyte reaction-stimulating ability.

Authors:  M Takiguchi; J P Ting; S C Buessow; C Boyer; Y Gillespie; J A Frelinger
Journal:  Eur J Immunol       Date:  1985-08       Impact factor: 5.532

8.  In vivo gene transfer with retroviral vector-producer cells for treatment of experimental brain tumors.

Authors:  K W Culver; Z Ram; S Wallbridge; H Ishii; E H Oldfield; R M Blaese
Journal:  Science       Date:  1992-06-12       Impact factor: 47.728

9.  A novel neutrophil-activating factor produced by human mononuclear phagocytes.

Authors:  P Peveri; A Walz; B Dewald; M Baggiolini
Journal:  J Exp Med       Date:  1988-05-01       Impact factor: 14.307

10.  A novel, NH2-terminal sequence-characterized human monokine possessing neutrophil chemotactic, skin-reactive, and granulocytosis-promoting activity.

Authors:  J Van Damme; J Van Beeumen; G Opdenakker; A Billiau
Journal:  J Exp Med       Date:  1988-04-01       Impact factor: 14.307
View more
  8 in total

Review 1.  Chemokines and glial cells: a complex network in the central nervous system.

Authors:  Elena Ambrosini; Francesca Aloisi
Journal:  Neurochem Res       Date:  2004-05       Impact factor: 3.996

2.  IL-8 is a mediator of NF-κB induced invasion by gliomas.

Authors:  Baisakhi Raychaudhuri; Michael A Vogelbaum
Journal:  J Neurooncol       Date:  2010-06-25       Impact factor: 4.130

3.  Adenovirus-mediated wild-type p53 expression induces apoptosis and suppresses tumorigenesis of experimental intracranial human malignant glioma.

Authors:  C Cirielli; K Inyaku; M C Capogrossi; X Yuan; J A Williams
Journal:  J Neurooncol       Date:  1999-06       Impact factor: 4.130

Review 4.  The role of interleukin-8 and its receptors in gliomagenesis and tumoral angiogenesis.

Authors:  Daniel J Brat; Anita C Bellail; Erwin G Van Meir
Journal:  Neuro Oncol       Date:  2005-04       Impact factor: 12.300

5.  Suppression of TGF-beta1 in human gliomas by retroviral gene transfection enhances susceptibility to LAK cells.

Authors:  R Yamanaka; R Tanaka; S Yoshida; T Saitoh; K Fujita; H Naganuma
Journal:  J Neurooncol       Date:  1999-05       Impact factor: 4.130

6.  Transfection of colorectal cancer cells with chemokine MCP-3 (monocyte chemotactic protein-3) gene retards tumor growth and inhibits tumor metastasis.

Authors:  Jin-Yue Hu; Guan-Cheng Li; Wen-Meng Wang; Jian-Gao Zhu; Yue-Fei Li; Guo-Hua Zhou; Qu-Bing Sun
Journal:  World J Gastroenterol       Date:  2002-12       Impact factor: 5.742

Review 7.  Anti-angiogenic gene therapy in the treatment of malignant gliomas.

Authors:  NaTosha N Gatson; E Antonio Chiocca; Balveen Kaur
Journal:  Neurosci Lett       Date:  2012-08-10       Impact factor: 3.046

8.  Induced interleukin-8 expression in gliomas by tumor-associated macrophages.

Authors:  Tse-Ming Hong; Lee-Jene Teng; Chia-Tung Shun; Mei-Chen Peng; Jui-Chang Tsai
Journal:  J Neurooncol       Date:  2009-01-21       Impact factor: 4.130
  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.