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Literature DB >> 6954072

Expression of HLA-DR and common acute lymphoblastic leukemia antigens on glioma cells.

Abstract

The expression on several established human glioma cell lines of two well-defined differentiation antigens, HLA-DR and the common acute lymphoblastic leukemia antigen (CALLA) has been demonstrated. Rabbit anti-CALLA antiserum and monoclonal anti-Ia antibodies specifically lysed glioma cells in the presence of complement. Absorption of anti-CALLA antiserum and anti-Ia antibodies by glioma cells abolished their cytotoxicity against blasts isolated from a common acute lymphoblastic leukemia. Immunoprecipitation of solubilized glioma cells by monoclonal anti-Ia antibodies revealed two polypeptide chains of 28 and 33 kDa, whereas the anti-CALLA antiserum precipitated a single polypeptide chain of 100 kDa.

Entities: Disease Gene Species

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Year: 1982 PMID： 6954072 DOI： 10.1002/eji.1830120418

Source DB: PubMed Journal: Eur J Immunol ISSN： 0014-2980 Impact factor: 5.532

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Cited

32 in total

1. Immunobiology of brain tumors.

Authors: E Frank; N de Tribolet
Journal: Neurosurg Rev Date: 1986 Impact factor: 3.042

2. Distribution of anti-Leu-7, anti-Leu-11a and anti-Leu-M1 immunoreactivity in the brain of the adult rat.

Authors: G Reifenberger; J K Mai; S Krajewski; W Wechsler
Journal: Cell Tissue Res Date: 1987-05 Impact factor: 5.249

Review 3. The immunobiology of human gliomas.

Authors: V Piguet; A C Diserens; S Carrel; J P Mach; N de Tribolet
Journal: Springer Semin Immunopathol Date: 1985

Review 4. The endothelium--astrocyte immune control system of the brain.

Authors: A Fontana; W Fierz
Journal: Springer Semin Immunopathol Date: 1985

5. Monocyte subpopulations in human gliomas: expression of Fc and complement receptors and correlation with tumor proliferation.

Authors: T Morimura; C Neuchrist; K Kitz; H Budka; O Scheiner; D Kraft; H Lassmann
Journal: Acta Neuropathol Date: 1990 Impact factor: 17.088

6. Histocompatibility antigens on astrocytoma cells.

Authors: N de Tribolet; S Carrel
Journal: J Neurol Neurosurg Psychiatry Date: 1982-10 Impact factor: 10.154

Review 7. Immunology of gliomas.

Authors: N de Tribolet
Journal: Childs Nerv Syst Date: 1989-04 Impact factor: 1.475