Literature DB >> 8501003

TAN-1057 A-D, new antibiotics with potent antibacterial activity against methicillin-resistant Staphylococcus aureus. Taxonomy, fermentation and biological activity.

N Katayama1, S Fukusumi, Y Funabashi, T Iwahi, H Ono.   

Abstract

Two Gram-negative bacteria were found to produce the new antibacterial antibiotics TAN-1057 A, B, C and D. The producing bacteria were characterized and designated as Flexibacter sp. PK-74 and PK-176. These antibiotics were active against Gram-negative and Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus. TAN-1057 A inhibited protein biosynthesis in Escherichia coli and S. aureus. It showed excellent protective effects against an experimental methicillin-resistant S. aureus infection in mice.

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Year:  1993        PMID: 8501003     DOI: 10.7164/antibiotics.46.606

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN: 0021-8820            Impact factor:   2.649


  7 in total

1.  Development of techniques to genetically manipulate members of the genera Cytophaga, Flavobacterium, Flexibacter, and Sporocytophaga.

Authors:  M J McBride; S A Baker
Journal:  Appl Environ Microbiol       Date:  1996-08       Impact factor: 4.792

2.  Characterization of a novel antibacterial agent that inhibits bacterial translation.

Authors:  Nina Böddeker; Gina Bahador; Craig Gibbs; Eric Mabery; John Wolf; Lianhong Xu; Julia Watson
Journal:  RNA       Date:  2002-09       Impact factor: 4.942

3.  Development of techniques for the genetic manipulation of the gliding bacterium Cytophaga johnsonae.

Authors:  M J McBride; M J Kempf
Journal:  J Bacteriol       Date:  1996-02       Impact factor: 3.490

4.  Ribosomal alterations contribute to bacterial resistance against the dipeptide antibiotic TAN 1057.

Authors:  E Limburg; R Gahlmann; H-P Kroll; D Beyer
Journal:  Antimicrob Agents Chemother       Date:  2004-02       Impact factor: 5.191

5.  Genomic and Chemical Decryption of the Bacteroidetes Phylum for Its Potential to Biosynthesize Natural Products.

Authors:  Stephan Brinkmann; Michael Kurz; Maria A Patras; Christoph Hartwig; Michael Marner; Benedikt Leis; André Billion; Yolanda Kleiner; Armin Bauer; Luigi Toti; Christoph Pöverlein; Peter E Hammann; Andreas Vilcinskas; Jens Glaeser; Marius Spohn; Till F Schäberle
Journal:  Microbiol Spectr       Date:  2022-04-20

6.  Marine Bacteria from Rocas Atoll as a Rich Source of Pharmacologically Active Compounds.

Authors:  Karen Y Velasco-Alzate; Anelize Bauermeister; Marcelo M P Tangerina; Tito M C Lotufo; Marcelo J P Ferreira; Paula C Jimenez; Gabriel Padilla; Norberto P Lopes; Letícia V Costa-Lotufo
Journal:  Mar Drugs       Date:  2019-11-28       Impact factor: 5.118

7.  Comparative genomic analysis of Flavobacteriaceae: insights into carbohydrate metabolism, gliding motility and secondary metabolite biosynthesis.

Authors:  Asimenia Gavriilidou; Johanna Gutleben; Dennis Versluis; Francesca Forgiarini; Mark W J van Passel; Colin J Ingham; Hauke Smidt; Detmer Sipkema
Journal:  BMC Genomics       Date:  2020-08-20       Impact factor: 3.969

  7 in total

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