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Literature DB >> 8500997

Screening microbial metabolites for new drugs--theoretical and practical issues.

G G Yarbrough¹, D P Taylor, R T Rowlands, M S Crawford, L L Lasure.

Abstract

Mesh：

Substances：
Anti-Bacterial Agents

Year: 1993 PMID： 8500997 DOI： 10.7164/antibiotics.46.535

Source DB: PubMed Journal: J Antibiot (Tokyo) ISSN： 0021-8820 Impact factor: 2.649

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Cited

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11 in total

1. Rapid method to estimate the presence of secondary metabolites in microbial extracts.

Authors: R E Higgs; J A Zahn; J D Gygi; M D Hilton
Journal: Appl Environ Microbiol Date: 2001-01 Impact factor: 4.792

2. Use of direct-infusion electrospray mass spectrometry to guide empirical development of improved conditions for expression of secondary metabolites from actinomycetes.

Authors: J A Zahn; R E Higgs; M D Hilton
Journal: Appl Environ Microbiol Date: 2001-01 Impact factor: 4.792

3. A method for the selection of production media for actinomycete strains based on their metabolite HPLC profiles.

Authors: José R Tormo; Juan B García; Mar DeAntonio; Julia Feliz; Aurora Mira; M Teresa Díez; Pilar Hernández; Fernando Peláez
Journal: J Ind Microbiol Biotechnol Date: 2003-09-09 Impact factor: 3.346

Review 4. Current approaches to exploit actinomycetes as a source of novel natural products.

Authors: Olga Genilloud; Ignacio González; Oscar Salazar; Jesus Martín; José Rubén Tormo; Francisca Vicente
Journal: J Ind Microbiol Biotechnol Date: 2010-10-08 Impact factor: 3.346

5. MbtH homology codes to identify gifted microbes for genome mining.

Authors: Richard H Baltz
Journal: J Ind Microbiol Biotechnol Date: 2013-11-07 Impact factor: 3.346

6. Rapid analysis of antibiotic-containing mixtures from fermentation broths by using liquid chromatography-electrospray ionization-mass spectrometry and matrix-assisted laser desorption ionization-time-of-flight-mass spectrometry.

Authors: B L Ackermann; B T Regg; L Colombo; S Stella; J E Coutant
Journal: J Am Soc Mass Spectrom Date: 1996-12 Impact factor: 3.109

Screening microbial metabolites for new drugs--theoretical and practical issues.

1. Rapid method to estimate the presence of secondary metabolites in microbial extracts.

2. Use of direct-infusion electrospray mass spectrometry to guide empirical development of improved conditions for expression of secondary metabolites from actinomycetes.

3. A method for the selection of production media for actinomycete strains based on their metabolite HPLC profiles.

Review 4. Current approaches to exploit actinomycetes as a source of novel natural products.

5. MbtH homology codes to identify gifted microbes for genome mining.

6. Rapid analysis of antibiotic-containing mixtures from fermentation broths by using liquid chromatography-electrospray ionization-mass spectrometry and matrix-assisted laser desorption ionization-time-of-flight-mass spectrometry.

Review 7. Recent examples of novel secondary metabolites.

8. Investigation of biological activity of soil fungal extracts and LC/MS-QTOF based metabolite profiling.

9. Anti-infective Potential of Hot-spring Bacteria.

10. Assessing the effects of adsorptive polymeric resin additions on fungal secondary metabolite chemical diversity.