Antimicrobial spectrum of bacteriocin-like substances produced by rumen staphylococci.

Five strains of rumen coagulase-negative adherent and ureolytic staphylococci were obtained as bacteria producing bacteriocin-like substances or lantibiotics. All examined staphylococci produced inhibitory agents which showed a wide range of inhibition against Gram-positive and Gram-negative indicator organisms from different sources. Clear zones of inhibition (diameter 1-6 mm) dominated. Most bacteriocin-like substances produced by the strains were stable and sensitive to trypsin, susceptible to chloroform vapours and heat-sensitive.