Literature DB >> 8485989

A method for testing the nonrandomness of chromosomal breakpoints.

J J Tai1, C D Hou, S Wang-Wuu, C H Wang, S Y Leu, K D Wuu.   

Abstract

Testing the nonrandomness of breakage at a chromosome band is an essential step fo identifying a fragile site. In this paper, we propose a method derived by using the relationship between the binomial and F distributions for testing nonrandomness. The method is simple in calculation. It was applied to the detection of fragile sites for Chinese patients with colorectal carcinoma.

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Year:  1993        PMID: 8485989     DOI: 10.1159/000133523

Source DB:  PubMed          Journal:  Cytogenet Cell Genet        ISSN: 0301-0171


  6 in total

1.  Cartographic study: breakpoints in 1574 families carrying human reciprocal translocations.

Authors:  O Cohen; C Cans; M Cuillel; J L Gilardi; H Roth; M A Mermet; P Jalbert; J Demongeot
Journal:  Hum Genet       Date:  1996-05       Impact factor: 4.132

2.  Identifying chromosomal fragile sites from individuals: a multinomial statistical model.

Authors:  U Böhm; P F Dahm; B F McAllister; I F Greenbaum
Journal:  Hum Genet       Date:  1995-03       Impact factor: 4.132

3.  Chromosomal distribution of schizophrenia susceptibility loci.

Authors:  Mostafa Saadat
Journal:  J Mol Neurosci       Date:  2013-05-17       Impact factor: 3.444

4.  Non-random distribution of gastric cancer susceptible loci on human chromosomes.

Authors:  Ghazale Mahjoub; Mostafa Saadat
Journal:  EXCLI J       Date:  2018-08-17       Impact factor: 4.068

5.  Distributions of susceptibility loci of Parkinson's disease and multiple sclerosis on human chromosomes.

Authors:  Mostafa Saadat
Journal:  EXCLI J       Date:  2014-06-24       Impact factor: 4.068

6.  Distributions of susceptibility loci to late onset Alzheimer's disease on human chromosomes.

Authors:  Mostafa Saadat
Journal:  EXCLI J       Date:  2016-06-22       Impact factor: 4.068

  6 in total

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