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Literature DB >> 8460635

A somatic cell hybrid map of the long arm of human chromosome 17, containing the familial breast cancer locus (BRCA1).

D M Black¹, H Nicolai, J Borrow, E Solomon.

Abstract

We describe a detailed somatic cell hybrid map of human chromosome 17q11.2-q23, containing the familial breast and ovarian cancer locus (BRCA1) and highly informative closely linked markers. An X-irradiation panel of 38 hamster/human and mouse/human hybrids with fragments of chromosome 17 was generated and characterized with 22 STS markers from this chromosome. A detailed map of 61 probes onto chromosome 17q, subdividing the chromosome arm into 25 regions, was done by using a panel of hybrids with well-defined breakpoints and nine chromosome-mediated gene transfectants. Our localization of RARA, TOP2, EDH17B1 and 2, and possibly WNT3, between THRA1 and D17S181, two markers known to flank BRCA1, suggests that any of these is a potential candidate for the BRCA1 locus. The marker D17S579 (Mfd188), which is believed to be very close to BRCA1, maps closest to the EDH17B genes.

Entities: Disease Gene Species

Mesh：

Substances：
DNA Probes
DNA, Neoplasm

Year: 1993 PMID： 8460635 PMCID： PMC1682064

Source DB: PubMed Journal: Am J Hum Genet ISSN： 0002-9297 Impact factor: 11.025

28 in total

1. Chromosome mapping of the human gene encoding the 68-kDa nuclear antigen (p68) by using the polymerase chain reaction.

Authors: R Iggo; A Gough; W Xu; D P Lane; N K Spurr
Journal: Proc Natl Acad Sci U S A Date: 1989-08 Impact factor: 11.205

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Journal: Genomics Date: 1989-05 Impact factor: 5.736

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Journal: Proc Natl Acad Sci U S A Date: 1990-09 Impact factor: 11.205

4. Association of low nm23 RNA levels in human primary infiltrating ductal breast carcinomas with lymph node involvement and other histopathological indicators of high metastatic potential.

Authors: G Bevilacqua; M E Sobel; L A Liotta; P S Steeg
Journal: Cancer Res Date: 1989-09-15 Impact factor: 12.701

Review 5. Progress towards identifying the neurofibromatosis (NF1) gene.

Authors: F S Collins; P O'Connell; B A Ponder; B R Seizinger
Journal: Trends Genet Date: 1989-07 Impact factor: 11.639

6. Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene.

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Journal: Science Date: 1987-01-09 Impact factor: 47.728

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Journal: Mol Endocrinol Date: 1990-02

8. Precise localization of NF1 to 17q11.2 by balanced translocation.

Authors: D H Ledbetter; D C Rich; P O'Connell; M Leppert; J C Carey
Journal: Am J Hum Genet Date: 1989-01 Impact factor: 11.025

9. Amplification of c-erbB-2 oncogene in human adenocarcinomas in vivo.

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Journal: Lancet Date: 1986-04-05 Impact factor: 79.321

10. Construction of a genetic map of human chromosome 17 by use of chromosome-mediated gene transfer.

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Journal: Proc Natl Acad Sci U S A Date: 1988-11 Impact factor: 11.205

12 in total

1. Assignment of the mulibrey nanism gene to 17q by linkage and linkage-disequilibrium analysis.

Authors: K Avela; M Lipsanen-Nyman; J Perheentupa; C Wallgren-Pettersson; S Marchand; S Fauré; P Sistonen; A de la Chapelle; A E Lehesjoki
Journal: Am J Hum Genet Date: 1997-04 Impact factor: 11.025

2. Van Buchem disease (hyperostosis corticalis generalisata) maps to chromosome 17q12-q21.

Authors: W Van Hul; W Balemans; E Van Hul; F G Dikkers; H Obee; R J Stokroos; P Hildering; F Vanhoenacker; G Van Camp; P J Willems
Journal: Am J Hum Genet Date: 1998-02 Impact factor: 11.025

Review 3. Irradiation and fusion gene transfer.

Authors: M A Walter; P N Goodfellow
Journal: Mol Biotechnol Date: 1995-04 Impact factor: 2.695

4. Genetic mapping of the BRCA1 region on chromosome 17q21.

Authors: H Albertsen; R Plaetke; L Ballard; E Fujimoto; J Connolly; E Lawrence; P Rodriguez; M Robertson; P Bradley; B Milner
Journal: Am J Hum Genet Date: 1994-03 Impact factor: 11.025

5. Further evidence of a relationship between the retinoic acid receptor alpha locus and nonsyndromic cleft lip with or without cleft palate (CL +/- P)

Authors: D Shaw; A Ray; M Marazita; L Field
Journal: Am J Hum Genet Date: 1993-11 Impact factor: 11.025

6. THRA1 and D17S183 flank an interval of < 4 cM for the breast-ovarian cancer gene (BRCA1) on chromosome 17q21.

Authors: A M Bowcock; L A Anderson; L S Friedman; D M Black; S Osborne-Lawrence; S E Rowell; J M Hall; E Solomon; M C King
Journal: Am J Hum Genet Date: 1993-04 Impact factor: 11.025

7. Genetic linkage analysis in familial breast and ovarian cancer: results from 214 families. The Breast Cancer Linkage Consortium.

Authors: D F Easton; D T Bishop; D Ford; G P Crockford
Journal: Am J Hum Genet Date: 1993-04 Impact factor: 11.025

8. Estimation of the RNU2 macrosatellite mutation rate by BRCA1 mutation tracing.

Authors: Chloé Tessereau; Yann Lesecque; Nastasia Monnet; Monique Buisson; Laure Barjhoux; Mélanie Léoné; Bingjian Feng; David E Goldgar; Olga M Sinilnikova; Sylvain Mousset; Laurent Duret; Sylvie Mazoyer
Journal: Nucleic Acids Res Date: 2014-07-17 Impact factor: 16.971

9. A radiation hybrid map of the BRCA1 region.

Authors: P O'Connell; H Albertsen; N Matsunami; T Taylor; J E Hundley; T L Johnson-Pais; B Reus; E Lawrence; L Ballard; R White
Journal: Am J Hum Genet Date: 1994-03 Impact factor: 11.025

10. Association of PHB 1630 C>T and MTHFR 677 C>T polymorphisms with breast and ovarian cancer risk in BRCA1/2 mutation carriers: results from a multicenter study.

Authors: A Jakubowska; D Rozkrut; A Antoniou; U Hamann; R J Scott; L McGuffog; S Healy; O M Sinilnikova; G Rennert; F Lejbkowicz; A Flugelman; I L Andrulis; G Glendon; H Ozcelik; M Thomassen; M Paligo; P Aretini; J Kantala; B Aroer; A von Wachenfeldt; A Liljegren; N Loman; K Herbst; U Kristoffersson; R Rosenquist; P Karlsson; M Stenmark-Askmalm; B Melin; K L Nathanson; S M Domchek; T Byrski; T Huzarski; J Gronwald; J Menkiszak; C Cybulski; P Serrano; A Osorio; T R Cajal; M Tsitlaidou; J Benítez; M Gilbert; M Rookus; C M Aalfs; I Kluijt; J L Boessenkool-Pape; H E J Meijers-Heijboer; J C Oosterwijk; C J van Asperen; M J Blok; M R Nelen; A M W van den Ouweland; C Seynaeve; R B van der Luijt; P Devilee; D F Easton; S Peock; D Frost; R Platte; S D Ellis; E Fineberg; D G Evans; F Lalloo; R Eeles; C Jacobs; J Adlard; R Davidson; D Eccles; T Cole; J Cook; A Godwin; B Bove; D Stoppa-Lyonnet; V Caux-Moncoutier; M Belotti; C Tirapo; S Mazoyer; L Barjhoux; N Boutry-Kryza; P Pujol; I Coupier; J-P Peyrat; P Vennin; D Muller; J-P Fricker; L Venat-Bouvet; O Th Johannsson; C Isaacs; R Schmutzler; B Wappenschmidt; A Meindl; N Arnold; R Varon-Mateeva; D Niederacher; C Sutter; H Deissler; S Preisler-Adams; J Simard; P Soucy; F Durocher; G Chenevix-Trench; J Beesley; X Chen; T Rebbeck; F Couch; X Wang; N Lindor; Z Fredericksen; V S Pankratz; P Peterlongo; B Bonanni; S Fortuzzi; B Peissel; C Szabo; P L Mai; J T Loud; J Lubinski
Journal: Br J Cancer Date: 2012-05-15 Impact factor: 7.640