Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 The Escherichia coli visA gene encodes ferrochelatase, the final enzyme of the heme biosynthetic pathway.

Literature DB >> 8458858

The Escherichia coli visA gene encodes ferrochelatase, the final enzyme of the heme biosynthetic pathway.

Abstract

An Escherichia coli mutant with a disrupted visA gene was defective in ferrochelatase activity but expressed wild-type levels of protoporphyrinogen oxidase activity. The visA coding region was placed under the transcriptional control of T7 RNA polymerase in an E. coli expression system, and the product was expressed as a 38-kDa protein. The overexpressed protein was purified to near homogeneity and was found to contain ferrochelatase activity. The data show that the visA gene encodes ferrochelatase, and we propose that it be renamed hemH to reflect that conclusion.

Entities: Chemical Gene Species

Mesh：

Substances：

Year: 1993 PMID： 8458858 PMCID： PMC204334 DOI： 10.1128/jb.175.7.2154-2156.1993

Source DB: PubMed Journal: J Bacteriol ISSN： 0021-9193 Impact factor: 3.490

29 in total

1. Organization of the terminal two enzymes of the heme biosynthetic pathway. Orientation of protoporphyrinogen oxidase and evidence for a membrane complex.

Authors: G C Ferreira; T L Andrew; S W Karr; H A Dailey
Journal: J Biol Chem Date: 1988-03-15 Impact factor: 5.157

2. Cloning of the Escherichia coli K-12 hemB gene.

Authors: J M Li; H Umanoff; R Proenca; C S Russell; S D Cosloy
Journal: J Bacteriol Date: 1988-02 Impact factor: 3.490

3. Vectors for selective expression of cloned DNAs by T7 RNA polymerase.

Authors: A H Rosenberg; B N Lade; D S Chui; S W Lin; J J Dunn; F W Studier
Journal: Gene Date: 1987 Impact factor: 3.688

4. Molecular cloning and sequencing of the hemD gene of Escherichia coli K-12 and preliminary data on the Uro operon.

Authors: A Sasarman; A Nepveu; Y Echelard; J Dymetryszyn; M Drolet; C Goyer
Journal: J Bacteriol Date: 1987-09 Impact factor: 3.490

5. Nucleotide sequence of the hemC locus encoding porphobilinogen deaminase of Escherichia coli K12.

Authors: S D Thomas; P M Jordan
Journal: Nucleic Acids Res Date: 1986-08-11 Impact factor: 16.971

6. Nucleotide sequence for the hemD gene of Escherichia coli encoding uroporphyrinogen III synthase and initial evidence for a hem operon.

Authors: P M Jordan; B I Mgbeje; S D Thomas; A F Alwan
Journal: Biochem J Date: 1988-01-15 Impact factor: 3.857

7. Accumulation of protoporphyrin IX in light-sensitive mutants of Escherichia coli.

Authors: K Miyamoto; K Nishimura; T Masuda; H Tsuji; H Inokuchi
Journal: FEBS Lett Date: 1992-10-05 Impact factor: 4.124

8. Protoporphyrin accumulation by mitogen stimulated lymphocytes and protoporphyrinogen oxidase activity in patients with porphyria variegata and erythropoietic protoporphyria: evidence for deficiency of protoporphyrinogen oxidase and ferrochelatase in both diseases.

Authors: L J Siepker; S Kramer
Journal: Br J Haematol Date: 1985-05 Impact factor: 6.998

8. Isolation and characterization of adenylate kinase (adk) mutations in Salmonella typhimurium which block the ability of glycine betaine to function as an osmoprotectant.

Authors: J A Gutierrez; L N Csonka
Journal: J Bacteriol Date: 1995-01 Impact factor: 3.490

9. TolC-dependent exclusion of porphyrins in Escherichia coli.

Authors: Ryoko Tatsumi; Masaaki Wachi
Journal: J Bacteriol Date: 2008-07-18 Impact factor: 3.490

10. Non-iron porphyrins cause tumbling to blue light by an Escherichia coli mutant defective in hemG.

Authors: H Yang; A Sasarman; H Inokuchi; J Adler
Journal: Proc Natl Acad Sci U S A Date: 1996-03-19 Impact factor: 11.205

The Escherichia coli visA gene encodes ferrochelatase, the final enzyme of the heme biosynthetic pathway.

1. Organization of the terminal two enzymes of the heme biosynthetic pathway. Orientation of protoporphyrinogen oxidase and evidence for a membrane complex.

2. Cloning of the Escherichia coli K-12 hemB gene.

3. Vectors for selective expression of cloned DNAs by T7 RNA polymerase.

4. Molecular cloning and sequencing of the hemD gene of Escherichia coli K-12 and preliminary data on the Uro operon.

5. Nucleotide sequence of the hemC locus encoding porphobilinogen deaminase of Escherichia coli K12.

6. Nucleotide sequence for the hemD gene of Escherichia coli encoding uroporphyrinogen III synthase and initial evidence for a hem operon.

7. Accumulation of protoporphyrin IX in light-sensitive mutants of Escherichia coli.

8. Protoporphyrin accumulation by mitogen stimulated lymphocytes and protoporphyrinogen oxidase activity in patients with porphyria variegata and erythropoietic protoporphyria: evidence for deficiency of protoporphyrinogen oxidase and ferrochelatase in both diseases.

9. Mapping of a new hem gene in Escherichia coli K12.

10. Porphyrin-accumulating mutants of Escherichia coli.

1. Effect of cobalt on Escherichia coli metabolism and metalloporphyrin formation.

Review 2. Linkage map of Escherichia coli K-12, edition 10: the traditional map.

3. Production and characterization of erythropoietic protoporphyric heterodimeric ferrochelatases.

4. Mutations in cytochrome assembly and periplasmic redox pathways in Bordetella pertussis.

Review 5. Structure and function of ferrochelatase.

6. Effect of omp10 or omp19 deletion on Brucella abortus outer membrane properties and virulence in mice.

7. Analysis of the Bradyrhizobium japonicum hemH gene and its expression in Escherichia coli.

8. Isolation and characterization of adenylate kinase (adk) mutations in Salmonella typhimurium which block the ability of glycine betaine to function as an osmoprotectant.

9. TolC-dependent exclusion of porphyrins in Escherichia coli.

10. Non-iron porphyrins cause tumbling to blue light by an Escherichia coli mutant defective in hemG.