| Literature DB >> 3276659 |
J M Li1, H Umanoff, R Proenca, C S Russell, S D Cosloy.
Abstract
An Escherichia coli heme-requiring, heme-permeable mutant had no detectable 5-aminolevulinate dehydratase or porphobilinogen deaminase activities. The gene which complemented this mutation was cloned to a high-copy-number plasmid, and porphobilinogen deaminase activity was restored to normal levels, but the synthesis of 5-aminolevulinate dehydratase increased 20- to 30-fold. A maxicell procedure confirmed that the gene cloned was hemB.Entities:
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Year: 1988 PMID: 3276659 PMCID: PMC210762 DOI: 10.1128/jb.170.2.1021-1025.1988
Source DB: PubMed Journal: J Bacteriol ISSN: 0021-9193 Impact factor: 3.490