Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Intermolecular mRNA-rRNA hybridization and the distribution of potential interaction regions in murine 18S rRNA.

Literature DB >> 8451167

Intermolecular mRNA-rRNA hybridization and the distribution of potential interaction regions in murine 18S rRNA.

Abstract

Intermolecular hybridization experiments show that murine 18S rRNA and 28S rRNA are capable of forming stable hybrid structures with mRNA from genes p53, c-myc and c-mos from the same species. Both 5'-uncoding and coding oncogene p53 mRNA regions contain fragments interacting with rRNA. Computer analysis revealed 18S rRNA fragments complementary to oligonucleotides frequently met in mRNA, which are potential hybridization regions (clinger-fragments). The distribution of clinger-fragments along 18S rRNA sequence is universal at least for one hundred murine mRNA sequences analyzed. Maximal frequencies of oligonucleotides complementary to 18S rRNA clinger-fragments are reliably (2-3 times) higher for mRNA than for intron sequences and randomly generated sequences. The results obtained suggest a possible role of clinger-fragments in translation processes as universal regions of mRNA binding.

Entities: Chemical Gene Species

Mesh：

Substances：

Year: 1993 PMID： 8451167 PMCID： PMC309236 DOI： 10.1093/nar/21.4.1007

Source DB: PubMed Journal: Nucleic Acids Res ISSN： 0305-1048 Impact factor: 16.971

21 in total

1. Mutations in 16S rRNA that affect UGA (stop codon)-directed translation termination.

Authors: H U Göringer; K A Hijazi; E J Murgola; A E Dahlberg
Journal: Proc Natl Acad Sci U S A Date: 1991-08-01 Impact factor: 11.205

2. Nucleotide sequence of the genome of a murine sarcoma virus.

Authors: C Van Beveren; F van Straaten; J A Galleshaw; I M Verma
Journal: Cell Date: 1981-11 Impact factor: 41.582

3. The nucleotide sequence of a rat 18 S ribosomal ribonucleic acid gene and a proposal for the secondary structure of 18 S ribosomal ribonucleic acid.

Authors: Y L Chan; R Gutell; H F Noller; I G Wool
Journal: J Biol Chem Date: 1984-01-10 Impact factor: 5.157

4. Enhanced graphic matrix analysis of nucleic acid and protein sequences.

Authors: J V Maizel; R P Lenk
Journal: Proc Natl Acad Sci U S A Date: 1981-12 Impact factor: 11.205

5. Conservation of the primary structure at the 3' end of 18S rRNA from eucaryotic cells.

Authors: O Hagenbüchle; M Santer; J A Steitz; R J Mans
Journal: Cell Date: 1978-03 Impact factor: 41.582

6. A possible novel interaction between the 3'-end of 18 S ribosomal RNA and the 5'-leader sequence of many eukaryotic messenger RNAs.

Authors: D R Sargan; S P Gregory; P H Butterworth
Journal: FEBS Lett Date: 1982-10-18 Impact factor: 4.124

7. Nucleotide sequence comparison of normal and translocated murine c-myc genes.

Authors: L W Stanton; P D Fahrlander; P M Tesser; K B Marcu
Journal: Nature Date: 1984 Aug 2-8 Impact factor: 49.962

8. Nucleotide sequence and formation of the transforming gene of a mouse sarcoma virus.

Authors: C Van Beveren; J A Galleshaw; V Jonas; A J Berns; R F Doolittle; D J Donoghue; I M Verma
Journal: Nature Date: 1981-01-22 Impact factor: 49.962

9. Complete nucleotide sequence of mouse 18 S rRNA gene: comparison with other available homologs.

Authors: F Raynal; B Michot; J P Bachellerie
Journal: FEBS Lett Date: 1984-02-27 Impact factor: 4.124

10. The 3'-terminal sequence of Escherichia coli 16S ribosomal RNA: complementarity to nonsense triplets and ribosome binding sites.

Authors: J Shine; L Dalgarno
Journal: Proc Natl Acad Sci U S A Date: 1974-04 Impact factor: 11.205

25 in total

1. Complementarity between the mRNA 5' untranslated region and 18S ribosomal RNA can inhibit translation.

Authors: S B Verrier; O Jean-Jean
Journal: RNA Date: 2000-04 Impact factor: 4.942

2. Patterns in interspecies similarity correlate with nucleotide composition in mammalian 3'UTRs.

Authors: Svetlana A Shabalina; Aleksey Y Ogurtsov; David J Lipman; Alexey S Kondrashov
Journal: Nucleic Acids Res Date: 2003-09-15 Impact factor: 16.971

Review 3. The ribosome filter hypothesis.

Authors: Vincent P Mauro; Gerald M Edelman
Journal: Proc Natl Acad Sci U S A Date: 2002-09-09 Impact factor: 11.205

Review 4. The ribosome filter redux.

Authors: Vincent P Mauro; Gerald M Edelman
Journal: Cell Cycle Date: 2007-06-29 Impact factor: 4.534

5. rRNA-complementarity in the 5' untranslated region of mRNA specifying the Gtx homeodomain protein: evidence that base- pairing to 18S rRNA affects translational efficiency.

Authors: M C Hu; P Tranque; G M Edelman; V P Mauro
Journal: Proc Natl Acad Sci U S A Date: 1999-02-16 Impact factor: 11.205