Literature DB >> 8443848

Minute ventilation during mask halothane anaesthesia in infants and children.

K A Brown1, B Bissonnette, H Holtby, S Ein, B Shandling.   

Abstract

The pattern of respiration in infants during anaesthesia is not well documented. In this study, minute ventilation (MV) during elective mask halothane anaesthesia (HA) was measured during spontaneous ventilation in infants (Group I) and children (Group II). Airflow was measured with pneumotachography (#0 Fleisch in Group I and #1 Fleisch in Group II). Analogue signals of pressure and flow were recorded on magnetic tape for off-line playback. The flow signal was mathematically integrated to volume. The surgical procedure was divided into three stages: A, B and C representing HA, surgical stimulation and emergence respectively. The pattern of respiration during spontaneous ventilation was described as tidal volume (VTx), respiratory frequency (fx), mean inspiratory flow (VT/TIx), inspiratory duty cycle (TI/TTotx) where the subscript x denoted the stage. Seven infants (2.7 +/- 0.5 mo, 5.8 +/- 0.5 kg) and five children (3.1 +/- 1.1 yr, 15.8 +/- 1.7 kg) were studied. There was no difference in MV between Groups I and II. Halothane anaesthesia in both groups was characterized by rapid shallow breathing: VTA was lower in Group I (2.90 +/- 0.8 ml.kg-1) than in Group II (3.74 +/- 0.40 ml.kg-1) (P < 0.05). Tidal volume was lower during anaesthesia than emergence in both groups (P < 0.05). There was no difference in VT/TIx between groups. The VT/TIA was lower than VT/TIC in Group I (P < 0.05) but not in Group II. There was no intra or intergroup difference in TI/TTot between stages. We suggest that during HA infants have a greater reduction in VT than children, which may predispose infants to hypercarbia during HA.

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Year:  1993        PMID: 8443848     DOI: 10.1007/BF03011306

Source DB:  PubMed          Journal:  Can J Anaesth        ISSN: 0832-610X            Impact factor:   5.063


  16 in total

1.  Drive and timing components of ventilation.

Authors:  J Milic-Emili; M M Grunstein
Journal:  Chest       Date:  1976-07       Impact factor: 9.410

2.  Effects of halothane, isoflurane and enflurane on ventilation in children.

Authors:  W S Wren; P Allen; A Synnott; D O'Keeffe; P O'Griofa
Journal:  Br J Anaesth       Date:  1987-04       Impact factor: 9.166

3.  The relationship between age and halothane requirement in man.

Authors:  G A Gregory; E I Eger; E S Munson
Journal:  Anesthesiology       Date:  1969-05       Impact factor: 7.892

4.  Median effective doses (ED50) of halothane in adults and children.

Authors:  H F Nicodemus; C Nassiri-Rahimi; L Bachman; T C Smith
Journal:  Anesthesiology       Date:  1969-10       Impact factor: 7.892

5.  Occlusion pressures in men rebreathing CO2 under methoxyflurane anesthesia.

Authors:  J P Derenne; J Couture; S Iscoe; A Whitelaw; J Milic-Emili
Journal:  J Appl Physiol       Date:  1976-05       Impact factor: 3.531

6.  Respiratory depression in children at different end tidal halothane concentrations.

Authors:  S G Lindahl; A P Yates; D J Hatch
Journal:  Anaesthesia       Date:  1987-12       Impact factor: 6.955

7.  Scaling respiratory pattern and respiratory 'drive'.

Authors:  D F Boggs; S M Tenney
Journal:  Respir Physiol       Date:  1984-12

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Authors:  W R Stahl
Journal:  J Appl Physiol       Date:  1967-03       Impact factor: 3.531

9.  Effects of halothane on medullary inspiratory neurons of the cat.

Authors:  M Tabatabai; L M Kitahata; O Yuge; M Matsumoto; J G Collins
Journal:  Anesthesiology       Date:  1987-02       Impact factor: 7.892

10.  Sites of action of halothane on respiratory pattern and ventilatory response to CO2 in cats.

Authors:  A Berkenbosch; J de Goede; C N Olievier; P H Quanjer
Journal:  Anesthesiology       Date:  1982-11       Impact factor: 7.892

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  3 in total

1.  Pattern of ventilation during halothane anaesthesia in infants less than two months of age.

Authors:  K A Brown
Journal:  Can J Anaesth       Date:  1996-02       Impact factor: 5.063

2.  Ventilatory depression by halothane in infants and children.

Authors:  K A Brown; O Reich; J H Bates
Journal:  Can J Anaesth       Date:  1995-07       Impact factor: 5.063

3.  Capnometry and the paediatric laryngeal mask airway.

Authors:  I A Spahr-Schopfer; B Bissonnette; E J Hartley
Journal:  Can J Anaesth       Date:  1993-11       Impact factor: 5.063

  3 in total

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