Literature DB >> 8439160

Cloning and sequencing of pepC, a cysteine aminopeptidase gene from Lactococcus lactis subsp. cremoris AM2.

M P Chapot-Chartier1, M Nardi, M C Chopin, A Chopin, J C Gripon.   

Abstract

A gene coding for an aminopeptidase (PepC) from Lactococcus lactis subsp. cremoris AM2 was cloned by complementation of an Escherichia coli mutant lacking aminopeptidase activity. The nucleotide sequence was determined. A portion of the predicted amino acid sequence of PepC (436 amino acids) showed strong homology to the active site of cysteine proteases. No signal sequence was found, indicating an intracellular location of the enzyme.

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Year:  1993        PMID： 8439160      PMCID： PMC202100          DOI： 10.1128/aem.59.1.330-333.1993

Source DB:  PubMed          Journal:  Appl Environ Microbiol        ISSN： 0099-2240            Impact factor:   4.792


  28 in total

1.  Nucleotide sequence of the pepN gene encoding aminopeptidase N of Escherichia coli.

Authors:  M Foglino; S Gharbi; A Lazdunski
Journal:  Gene       Date:  1986       Impact factor: 3.688

2.  Purification and Characterization of an Aminopeptidase from Lactococcus lactis subsp. cremoris AM2.

Authors:  E Neviani; C Y Boquien; V Monnet; L P Thanh; J C Gripon
Journal:  Appl Environ Microbiol       Date:  1989-09       Impact factor: 4.792

3.  Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

Authors:  H Towbin; T Staehelin; J Gordon
Journal:  Proc Natl Acad Sci U S A       Date:  1979-09       Impact factor: 11.205

4.  Cleavage of structural proteins during the assembly of the head of bacteriophage T4.

Authors:  U K Laemmli
Journal:  Nature       Date:  1970-08-15       Impact factor: 49.962

5.  Characterization and overexpression of the Lactococcus lactis pepN gene and localization of its product, aminopeptidase N.

Authors:  I J van Alen-Boerrigter; R Baankreis; W M de Vos
Journal:  Appl Environ Microbiol       Date:  1991-09       Impact factor: 4.792

Review 6.  Gene expression in Lactococcus lactis.

Authors:  M van de Guchte; J Kok; G Venema
Journal:  FEMS Microbiol Rev       Date:  1992-02       Impact factor: 16.408

7.  Bleomycin hydrolase: molecular cloning, sequencing, and biochemical studies reveal membership in the cysteine proteinase family.

Authors:  S M Sebti; J E Mignano; J P Jani; S Srimatkandada; J S Lazo
Journal:  Biochemistry       Date:  1989-08-08       Impact factor: 3.162

8.  Amino acid sequence deduced from a rat kidney cDNA suggests it encodes the Zn-peptidase aminopeptidase N.

Authors:  V M Watt; C C Yip
Journal:  J Biol Chem       Date:  1989-04-05       Impact factor: 5.157

9.  Properties of a novel D-stereospecific aminopeptidase from Ochrobactrum anthropi.

Authors:  Y Asano; A Nakazawa; Y Kato; K Kondo
Journal:  J Biol Chem       Date:  1989-08-25       Impact factor: 5.157

10.  Peptidase mutants of Salmonella typhimurium.

Authors:  C G Miller; K Mackinnon
Journal:  J Bacteriol       Date:  1974-10       Impact factor: 3.490
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  15 in total

1.  Atypical genetic locus associated with constitutive production of enterocin B by Enterococcus faecium BFE 900.

Authors:  C M Franz; R W Worobo; L E Quadri; U Schillinger; W H Holzapfel; J C Vederas; M E Stiles
Journal:  Appl Environ Microbiol       Date:  1999-05       Impact factor: 4.792

2.  Experimental evidence for the essential role of the C-terminal residue in the strict aminopeptidase activity of the thiol aminopeptidase PepC, a bacterial bleomycin hydrolase.

Authors:  L Mata; M Erra-Pujada; J C Gripon; M Y Mistou
Journal:  Biochem J       Date:  1997-12-01       Impact factor: 3.857

Review 3.  The proteolytic systems of lactic acid bacteria.

Authors:  E R Kunji; I Mierau; A Hagting; B Poolman; W N Konings
Journal:  Antonie Van Leeuwenhoek       Date:  1996-10       Impact factor: 2.271

4.  TcyR regulates L-cystine uptake via the TcyABC transporter in Streptococcus mutans.

Authors:  Jennifer Kim; Dilani B Senadheera; Céline M Lévesque; Dennis G Cvitkovitch
Journal:  FEMS Microbiol Lett       Date:  2012-01-17       Impact factor: 2.742

5.  Characterization of the Lactobacillus helveticus CNRZ32 pepC gene.

Authors:  L Fernández; T Bhowmik; J L Steele
Journal:  Appl Environ Microbiol       Date:  1994-01       Impact factor: 4.792

6.  Transcriptional pattern of genes coding for the proteolytic system of Lactococcus lactis and evidence for coordinated regulation of key enzymes by peptide supply.

Authors:  E Guédon; P Renault; S D Ehrlich; C Delorme
Journal:  J Bacteriol       Date:  2001-06       Impact factor: 3.490

7.  Tripeptidase gene (pepT) of Lactococcus lactis: molecular cloning and nucleotide sequencing of pepT and construction of a chromosomal deletion mutant.

Authors:  I Mierau; A J Haandrikman; O Velterop; P S Tan; K L Leenhouts; W N Konings; G Venema; J Kok
Journal:  J Bacteriol       Date:  1994-05       Impact factor: 3.490

8.  Physical and genetic map of the Lactococcus lactis subsp. cremoris MG1363 chromosome: comparison with that of Lactococcus lactis subsp. lactis IL 1403 reveals a large genome inversion.

Authors:  P Le Bourgeois; M Lautier; L van den Berghe; M J Gasson; P Ritzenthaler
Journal:  J Bacteriol       Date:  1995-05       Impact factor: 3.490

9.  Cloning and sequencing of the gene for a lactococcal endopeptidase, an enzyme with sequence similarity to mammalian enkephalinase.

Authors:  I Mierau; P S Tan; A J Haandrikman; B Mayo; J Kok; K J Leenhouts; W N Konings; G Venema
Journal:  J Bacteriol       Date:  1993-04       Impact factor: 3.490

10.  Cloning and characterization of brnQ, a gene encoding a low-affinity, branched-chain amino acid carrier in Lactobacillus delbrückii subsp. lactis DSM7290.

Authors:  K Stucky; A Hagting; J R Klein; H Matern; B Henrich; W N Konings; R Plapp
Journal:  Mol Gen Genet       Date:  1995-12-20
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