Literature DB >> 8412810

Expression of recombinant vitamin K-dependent proteins in mammalian cells: factors IX and VII.

K L Berkner1.   

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Year:  1993        PMID: 8412810     DOI: 10.1016/0076-6879(93)22029-f

Source DB:  PubMed          Journal:  Methods Enzymol        ISSN: 0076-6879            Impact factor:   1.600


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  18 in total

1.  Fish as bioreactors: transgene expression of human coagulation factor VII in fish embryos.

Authors:  Gyulin Hwang; Ferenc Müller; M Aziz Rahman; Darren W Williams; Paul J Murdock; K John Pasi; Geoffrey Goldspink; Hamid Farahmand; Norman Maclean
Journal:  Mar Biotechnol (NY)       Date:  2004-04-29       Impact factor: 3.619

2.  r-VKORC1 expression in factor IX BHK cells increases the extent of factor IX carboxylation but is limited by saturation of another carboxylation component or by a shift in the rate-limiting step.

Authors:  Kevin W Hallgren; Wen Qian; Anna V Yakubenko; Kurt W Runge; Kathleen L Berkner
Journal:  Biochemistry       Date:  2006-05-02       Impact factor: 3.162

3.  Methylation of γ-carboxylated Glu (Gla) allows detection by liquid chromatography-mass spectrometry and the identification of Gla residues in the γ-glutamyl carboxylase.

Authors:  K W Hallgren; D Zhang; M Kinter; B Willard; K L Berkner
Journal:  J Proteome Res       Date:  2013-05-10       Impact factor: 4.466

4.  Targeting tumor vasculature endothelial cells and tumor cells for immunotherapy of human melanoma in a mouse xenograft model.

Authors:  Z Hu; Y Sun; A Garen
Journal:  Proc Natl Acad Sci U S A       Date:  1999-07-06       Impact factor: 11.205

5.  Warfarin alters vitamin K metabolism: a surprising mechanism of VKORC1 uncoupling necessitates an additional reductase.

Authors:  Mark A Rishavy; Kevin W Hallgren; Lee Wilson; Savita Singh; Kurt W Runge; Kathleen L Berkner
Journal:  Blood       Date:  2018-03-28       Impact factor: 22.113

6.  Vitamin K-dependent carboxylation of the carboxylase.

Authors:  K L Berkner; B N Pudota
Journal:  Proc Natl Acad Sci U S A       Date:  1998-01-20       Impact factor: 11.205

Review 7.  Vitamin K oxygenation, glutamate carboxylation, and processivity: defining the three critical facets of catalysis by the vitamin K-dependent carboxylase.

Authors:  Mark A Rishavy; Kathleen L Berkner
Journal:  Adv Nutr       Date:  2012-03-01       Impact factor: 8.701

8.  Fixing human factor IX (fIX): correction of a cryptic RNA splice enables the production of biologically active fIX in the mammary gland of transgenic mice.

Authors:  F Yull; G Harold; R Wallace; A Cowper; J Percy; I Cottingham; A J Clark
Journal:  Proc Natl Acad Sci U S A       Date:  1995-11-21       Impact factor: 11.205

9.  Targeting tissue factor on tumour cells and angiogenic vascular endothelial cells by factor VII-targeted verteporfin photodynamic therapy for breast cancer in vitro and in vivo in mice.

Authors:  Zhiwei Hu; Benqiang Rao; Shimin Chen; Jinzhong Duanmu
Journal:  BMC Cancer       Date:  2010-05-26       Impact factor: 4.430

10.  Insight into the coupling mechanism of the vitamin K-dependent carboxylase: mutation of histidine 160 disrupts glutamic acid carbanion formation and efficient coupling of vitamin K epoxidation to glutamic acid carboxylation.

Authors:  Mark A Rishavy; Kathleen L Berkner
Journal:  Biochemistry       Date:  2008-08-22       Impact factor: 3.162

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