Literature DB >> 8405939

Investigation of the Pseudomonas aeruginosa ampR gene and its role at the chromosomal ampC beta-lactamase promoter.

J Lodge1, S Busby, L Piddock.   

Abstract

The complete sequence of the Pseudomonas aeruginosa beta-lactamase regulator gene ampR has been determined. The amino acid sequence encoded by this gene is compared with other members of the LysR family of transcription factors. The P. aeruginosa ampC promoter was subcloned and gel mobility shift assays were used to demonstrate specific binding of AmpR to the ampC promoter region.

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Year:  1993        PMID： 8405939     DOI： 10.1111/j.1574-6968.1993.tb06404.x

Source DB:  PubMed          Journal:  FEMS Microbiol Lett        ISSN： 0378-1097            Impact factor:   2.742


  27 in total

1.  Hypersusceptibility of the Pseudomonas aeruginosa nfxB mutant to beta-lactams due to reduced expression of the ampC beta-lactamase.

Authors:  N Masuda; E Sakagawa; S Ohya; N Gotoh; T Nishino
Journal:  Antimicrob Agents Chemother       Date:  2001-04       Impact factor: 5.191

Review 2.  ISCR elements: novel gene-capturing systems of the 21st century?

Authors:  Mark A Toleman; Peter M Bennett; Timothy R Walsh
Journal:  Microbiol Mol Biol Rev       Date:  2006-06       Impact factor: 11.056

Review 3.  Pseudomonas aeruginosa AmpR: an acute-chronic switch regulator.

Authors:  Deepak Balasubramanian; Hansi Kumari; Kalai Mathee
Journal:  Pathog Dis       Date:  2015-02-26       Impact factor: 3.166

4.  Characterization of the penA and penR genes of Burkholderia cepacia 249 which encode the chromosomal class A penicillinase and its LysR-type transcriptional regulator.

Authors:  S Trépanier; A Prince; A Huletsky
Journal:  Antimicrob Agents Chemother       Date:  1997-11       Impact factor: 5.191

5.  Pseudomonas aeruginosa isolates from patients with cystic fibrosis have different beta-lactamase expression phenotypes but are homogeneous in the ampC-ampR genetic region.

Authors:  J I Campbell; O Ciofu; N Høiby
Journal:  Antimicrob Agents Chemother       Date:  1997-06       Impact factor: 5.191

Review 6.  Cell-Wall Recycling of the Gram-Negative Bacteria and the Nexus to Antibiotic Resistance.

Authors:  David A Dik; Jed F Fisher; Shahriar Mobashery
Journal:  Chem Rev       Date:  2018-05-30       Impact factor: 60.622

7.  Muropeptide Binding and the X-ray Structure of the Effector Domain of the Transcriptional Regulator AmpR of Pseudomonas aeruginosa.

Authors:  David A Dik; Teresa Domínguez-Gil; Mijoon Lee; Dusan Hesek; Byungjin Byun; Jennifer Fishovitz; Bill Boggess; Lance M Hellman; Jed F Fisher; Juan A Hermoso; Shahriar Mobashery
Journal:  J Am Chem Soc       Date:  2017-01-17       Impact factor: 15.419

8.  Naturally occurring Class A ss-lactamases from the Burkholderia cepacia complex.

Authors:  Laurent Poirel; José-Manuel Rodriguez-Martinez; Patrick Plésiat; Patrice Nordmann
Journal:  Antimicrob Agents Chemother       Date:  2008-12-15       Impact factor: 5.191

9.  Role of Pseudomonas aeruginosa AmpR on β-lactam and non-β-lactam transient cross-resistance upon pre-exposure to subinhibitory concentrations of antibiotics.

Authors:  Hansi Kumari; Deepak Balasubramanian; Diansy Zincke; Kalai Mathee
Journal:  J Med Microbiol       Date:  2014-01-25       Impact factor: 2.472

10.  Inactivation of the glycoside hydrolase NagZ attenuates antipseudomonal beta-lactam resistance in Pseudomonas aeruginosa.

Authors:  Azizah Asgarali; Keith A Stubbs; Antonio Oliver; David J Vocadlo; Brian L Mark
Journal:  Antimicrob Agents Chemother       Date:  2009-03-09       Impact factor: 5.191
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