Literature DB >> 8394839

Scavenging of superoxide anions by spice principles.

T P Krishnakantha1, B R Lokesh.   

Abstract

Effect of spice principles on scavenging of superoxide anion has been investigated. The superoxide anions, as measured by nitrobluetetrazolium (NBT) reduction in xanthine-xanthine oxidase system, were inhibited by superoxide dismutase, spice principles eugenol (cloves) and cuminaldehyde (cumin), antioxidants, butylated hydroxy toluene and butylated hydroxyanisole in a dose-dependent manner. The K(i) values for the inhibition of NBT reduction by eugenol and cuminaldehyde were 64 microM and 120 microM respectively. Zingerone (ginger) and linalool (coriander) inhibited NBT reduction to a maximum of 23 and 28% respectively. However, piperine (black pepper) and turmeric extracts (aqueous and acid) failed to scavenge superoxide anions.

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Year:  1993        PMID： 8394839

Source DB:  PubMed          Journal:  Indian J Biochem Biophys        ISSN： 0301-1208            Impact factor:   1.918


  18 in total

1.  Pseudotannins self-assembled into antioxidant complexes.

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Journal:  Soft Matter       Date:  2015-08-27       Impact factor: 3.679

2.  Inhibition of xanthine oxidase-xanthine-iron mediated lipid peroxidation by eugenol in liposomes.

Authors:  E Nagababu; N Lakshmaiah
Journal:  Mol Cell Biochem       Date:  1997-01       Impact factor: 3.396

3.  Zingerone [4-(4-hydroxy-3-methoxyphenyl)-2-butanone] prevents 6-hydroxydopamine-induced dopamine depression in mouse striatum and increases superoxide scavenging activity in serum.

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4.  Effects of zingerone [4-(4-hydroxy-3-methoxyphenyl)-2-butanone] and eugenol [2-methoxy-4-(2-propenyl)phenol] on the pathological progress in the 6-hydroxydopamine-induced Parkinson's disease mouse model.

Authors:  Hideaki Kabuto; Tomoko T Yamanushi
Journal:  Neurochem Res       Date:  2011-07-19       Impact factor: 3.996

5.  Evaluation of the antioxidant effects of Ziziphus mauritiana Lam. Leaf extracts against chronic ethanol-induced hepatotoxicity in rat liver.

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Review 7.  Active ingredients of ginger as potential candidates in the prevention and treatment of diseases via modulation of biological activities.

Authors:  Arshad H Rahmani; Fahad M Al Shabrmi; Salah M Aly
Journal:  Int J Physiol Pathophysiol Pharmacol       Date:  2014-07-12

8.  Effects of cumin extract on oxLDL, paraoxanase 1 activity, FBS, total cholesterol, triglycerides, HDL-C, LDL-C, Apo A1, and Apo B in in the patients with hypercholesterolemia.

Authors:  Keihan Ghatreh Samani; Effat Farrokhi
Journal:  Int J Health Sci (Qassim)       Date:  2014-01

9.  Investigation of the protective effects of horse mushroom (Agaricus arvensis Schaeff.) against carbon tetrachloride-induced oxidative stress in rats.

Authors:  Abdulahad Dogan; Abdullah Dalar; Cemil Sadullahoglu; Abdulhamit Battal; Yusuf Uzun; Ismail Celik; Kenan Demirel
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10.  Evaluation of lenticular antioxidant and redox system components in the lenses of acetyl-L-carnitine treatment in BSO-induced glutathione deprivation.

Authors:  R Elanchezhian; M Sakthivel; M Isai; P Geraldine; P A Thomas
Journal:  Mol Vis       Date:  2009-07-31       Impact factor: 2.367
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