Literature DB >> 83927

Effects of distamycin A on human leukocytes in vitro.

G Prantera, S Pimpinelli, A Rocchi.   

Abstract

Distamycin A, an oligopeptide antibiotic, supplied at various concentrations for 24 h to human leukocytes in culture, has induced the appearance on some chromosomes of specific areas lacking spiralization. In particular, the centromeric regions of chromosomes 1, 3 and one C-group chromosome and the distal part of the long arm of the Y chromosome were despiralized. The possible nature of these regions is discussed.

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Year:  1979        PMID: 83927     DOI: 10.1159/000131310

Source DB:  PubMed          Journal:  Cytogenet Cell Genet        ISSN: 0301-0171


  11 in total

1.  DA/DAPI-fluorescent heteromorphism of human Y chromosome.

Authors:  M S Lin; A Zhang; M G Wilson; A Fujimoto
Journal:  Hum Genet       Date:  1988-05       Impact factor: 4.132

2.  Inhibition of condensation in human chromosomes induced by the thymidine analogue 5-iododeoxyuridine.

Authors:  G Ott; T Haaf; M Schmid
Journal:  Chromosome Res       Date:  1998-09       Impact factor: 5.239

3.  An improved method for Y-body identification and confirmation of a high incidence of YY sperm nuclei.

Authors:  M Klasen; M Schmid
Journal:  Hum Genet       Date:  1981       Impact factor: 4.132

4.  Demonstration of Y/autosomal translocations using distamycin A.

Authors:  M Schmid
Journal:  Hum Genet       Date:  1979       Impact factor: 4.132

5.  Satellited Y chromosomes: structure, origin, and clinical significance.

Authors:  M Schmid; T Haaf; E Solleder; W Schempp; M Leipoldt; H Heilbronner
Journal:  Hum Genet       Date:  1984       Impact factor: 4.132

Review 6.  Aspects of evaluation, significance, and evolution of human C-band heteromorphism.

Authors:  B Erdtmann
Journal:  Hum Genet       Date:  1982       Impact factor: 4.132

Review 7.  A synopsis of the human Y chromosome.

Authors:  E M Bühler
Journal:  Hum Genet       Date:  1980       Impact factor: 4.132

8.  A new case of Y to X translocation in a female.

Authors:  T Hecht; H J Cooke; M Cerrillo; B Meer; G Reck; H Hameister
Journal:  Hum Genet       Date:  1980       Impact factor: 4.132

9.  The use of distamycin A in human lymphocyte cultures.

Authors:  M Schmid; D A Hungerford; A Poppen; W Engel
Journal:  Hum Genet       Date:  1984       Impact factor: 4.132

10.  Heritable fragile sites on human chromosomes. XI. Factors affecting expression of fragile sites at 10q25, 16q22, and 17p12.

Authors:  G R Sutherland; P B Jacky; E G Baker
Journal:  Am J Hum Genet       Date:  1984-01       Impact factor: 11.025

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