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Literature DB >> 8386260

Apoptosis induced by tumor necrosis factor in cells chronically infected with feline immunodeficiency virus.

K Ohno¹, T Nakano, Y Matsumoto, T Watari, R Goitsuka, H Nakayama, H Tsujimoto, A Hasegawa.

Abstract

Tumor necrosis factor alpha (TNF-alpha) induced morphologic changes such as chromatin condensation and cell shrinkage in a feline fibroblastic cell line (CRFK) chronically infected with feline immunodeficiency virus (FIV) but not in uninfected CRFK cells. DNA extracted from TNF-alpha-treated CRFK cells infected with FIV showed a ladder of nucleosomal DNA, indicating that this cytocidal effect by TNF-alpha was due to programmed cell death, or apoptosis. These findings may have implications for understanding the pathogenesis of FIV infection and for the design of specific therapeutic strategies for AIDS in humans as well as cats.

Entities: Disease Gene Species

Mesh：

Substances：

Year: 1993 PMID： 8386260 PMCID： PMC237560

Source DB: PubMed Journal: J Virol ISSN： 0022-538X Impact factor: 5.103

26 in total

1. Apoptosis as a mechanism of cell death in cultured T lymphoblasts acutely infected with HIV-1.

Authors: C Terai; R S Kornbluth; C D Pauza; D D Richman; D A Carson
Journal: J Clin Invest Date: 1991-05 Impact factor: 14.808

2. Activation of programmed cell death by recombinant human tumor necrosis factor plus topoisomerase II-targeted drugs in L929 tumor cells.

Authors: N Kyprianou; R B Alexander; J T Isaacs
Journal: J Natl Cancer Inst Date: 1991-03-06 Impact factor: 13.506

Review 3. The human immunodeficiency virus: infectivity and mechanisms of pathogenesis.

Authors: A S Fauci
Journal: Science Date: 1988-02-05 Impact factor: 47.728

4. Cytopathic effect of human immunodeficiency virus in T4 cells is linked to the last stage of virus infection.

Authors: R Leonard; D Zagury; I Desportes; J Bernard; J F Zagury; R C Gallo
Journal: Proc Natl Acad Sci U S A Date: 1988-05 Impact factor: 11.205

5. Development, characterization, and viral susceptibility of a feline (Felis catus) renal cell line (CRFK).

Authors: R A Crandell; C G Fabricant; W A Nelson-Rees
Journal: In Vitro Date: 1973 Nov-Dec

6. Progressive immune dysfunction in cats experimentally infected with feline immunodeficiency virus.

Authors: M Torten; M Franchini; J E Barlough; J W George; E Mozes; H Lutz; N C Pedersen
Journal: J Virol Date: 1991-05 Impact factor: 5.103

7. Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death.

Authors: D Hockenbery; G Nuñez; C Milliman; R D Schreiber; S J Korsmeyer
Journal: Nature Date: 1990-11-22 Impact factor: 49.962

8. Tumor promoter, TPA, enhances replication of HTLV-III/LAV.

Authors: S Harada; Y Koyanagi; H Nakashima; N Kobayashi; N Yamamoto
Journal: Virology Date: 1986-10-30 Impact factor: 3.616

9. In vitro anti-human immunodeficiency virus activities of tumor necrosis factor-alpha and interferon-gamma.

Authors: G H Wong; J F Krowka; D P Stites; D V Goeddel
Journal: J Immunol Date: 1988-01-01 Impact factor: 5.422

10. Isolation of a T-lymphotropic virus from domestic cats with an immunodeficiency-like syndrome.

Authors: N C Pedersen; E W Ho; M L Brown; J K Yamamoto
Journal: Science Date: 1987-02-13 Impact factor: 47.728

25 in total

1. Dynamics of nontypical apoptotic morphological changes visualized by green fluorescent protein in living cells with infectious pancreatic necrosis virus infection.

Authors: J R Hong; T L Lin; J Y Yang; Y L Hsu; J L Wu
Journal: J Virol Date: 1999-06 Impact factor: 5.103

10. Immune activation and viral burden in acute disease induced by simian immunodeficiency virus SIVsmmPBj14: correlation between in vitro and in vivo events.

Authors: R Schwiebert; P N Fultz
Journal: J Virol Date: 1994-09 Impact factor: 5.103

Apoptosis induced by tumor necrosis factor in cells chronically infected with feline immunodeficiency virus.

1. Apoptosis as a mechanism of cell death in cultured T lymphoblasts acutely infected with HIV-1.

2. Activation of programmed cell death by recombinant human tumor necrosis factor plus topoisomerase II-targeted drugs in L929 tumor cells.

Review 3. The human immunodeficiency virus: infectivity and mechanisms of pathogenesis.

4. Cytopathic effect of human immunodeficiency virus in T4 cells is linked to the last stage of virus infection.

5. Development, characterization, and viral susceptibility of a feline (Felis catus) renal cell line (CRFK).

6. Progressive immune dysfunction in cats experimentally infected with feline immunodeficiency virus.

7. Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death.

8. Tumor promoter, TPA, enhances replication of HTLV-III/LAV.

9. In vitro anti-human immunodeficiency virus activities of tumor necrosis factor-alpha and interferon-gamma.

10. Isolation of a T-lymphotropic virus from domestic cats with an immunodeficiency-like syndrome.

1. Dynamics of nontypical apoptotic morphological changes visualized by green fluorescent protein in living cells with infectious pancreatic necrosis virus infection.

2. Rabies virus infects mouse and human lymphocytes and induces apoptosis.

3. Detection of apoptosis induced in peripheral blood lymphocytes from cats infected with feline immunodeficiency virus.

4. Apoptosis as a cause of death in measles virus-infected cells.

5. Programmed cell death in brains of HIV-1-positive AIDS and pre-AIDS patients.

6. Apoptosis: a mechanism of cell killing by influenza A and B viruses.

Review 7. Feline immunodeficiency virus: an interesting model for AIDS studies and an important cat pathogen.

8. Induction of apoptosis in a T lymphoblastoid cell line infected with feline immunodeficiency virus.

9. Relationship between tumor necrosis factor alpha and feline immunodeficiency virus expressions.

10. Immune activation and viral burden in acute disease induced by simian immunodeficiency virus SIVsmmPBj14: correlation between in vitro and in vivo events.