Literature DB >> 8341642

Direct selection of antibodies that coordinate metals from semisynthetic combinatorial libraries.

C F Barbas1, J S Rosenblum, R A Lerner.   

Abstract

An iterative strategy for the selection of catalytic metalloantibodies is described. The first stage of this strategy is validated by the selection of semisynthetic antibodies that coordinate a variety of different metal ions and the metal oxide magnetite. These results have implications not only for the development of catalytic metalloantibodies but also for the development of reagents for magnetic resonance imaging, delivery of radioisotopes, and purification of recombinant proteins.

Entities:  

Mesh：

Substances：

Year:  1993        PMID： 8341642      PMCID： PMC46936          DOI： 10.1073/pnas.90.14.6385

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  20 in total

1.  A copper-binding immunoglobulin from a myeloma patient. Studies of the copper-binding site.

Authors:  B L Baker; D E Hultquist
Journal:  J Biol Chem       Date:  1978-12-10       Impact factor: 5.157

Review 2.  Applications of bacterial magnets.

Authors:  T Matsunaga
Journal:  Trends Biotechnol       Date:  1991-03       Impact factor: 19.536

Review 3.  Zinc coordination, function, and structure of zinc enzymes and other proteins.

Authors:  B L Vallee; D S Auld
Journal:  Biochemistry       Date:  1990-06-19       Impact factor: 3.162

4.  Assembly of combinatorial antibody libraries on phage surfaces: the gene III site.

Authors:  C F Barbas; A S Kang; R A Lerner; S J Benkovic
Journal:  Proc Natl Acad Sci U S A       Date:  1991-09-15       Impact factor: 11.205

5.  Monoclonal antibodies specific for mercuric ions.

Authors:  D E Wylie; D Lu; L D Carlson; R Carlson; K F Babacan; S M Schuster; F W Wagner
Journal:  Proc Natl Acad Sci U S A       Date:  1992-05-01       Impact factor: 11.205

6.  Chiral metal complexes as discriminating molecular catalysts.

Authors:  R Noyori
Journal:  Science       Date:  1990-06-08       Impact factor: 47.728

7.  Metalloantibodies.

Authors:  B L Iverson; S A Iverson; V A Roberts; E D Getzoff; J A Tainer; S J Benkovic; R A Lerner
Journal:  Science       Date:  1990-08-10       Impact factor: 47.728

8.  Canonical structures for the hypervariable regions of immunoglobulins.

Authors:  C Chothia; A M Lesk
Journal:  J Mol Biol       Date:  1987-08-20       Impact factor: 5.469

Review 9.  Copper protein structures.

Authors:  E T Adman
Journal:  Adv Protein Chem       Date:  1991

Review 10.  Metal-binding sites in proteins.

Authors:  J A Tainer; V A Roberts; E D Getzoff
Journal:  Curr Opin Biotechnol       Date:  1991-08       Impact factor: 9.740
View more
  19 in total

Review 1.  Generation of recombinant antibodies.

Authors:  S M Kipriyanov; M Little
Journal:  Mol Biotechnol       Date:  1999-09       Impact factor: 2.695

2.  A rationally designed agonist antibody fragment that functionally mimics thrombopoietin.

Authors:  Shana Frederickson; Mark W Renshaw; Bing Lin; Lynette M Smith; Peter Calveley; Jeremy P Springhorn; Krista Johnson; Yi Wang; Xiao Su; Yamin Shen; Katherine S Bowdish
Journal:  Proc Natl Acad Sci U S A       Date:  2006-09-14       Impact factor: 11.205

3.  Interfacial metal and antibody recognition.

Authors:  Tongqing Zhou; Dean H Hamer; Wayne A Hendrickson; Quentin J Sattentau; Peter D Kwong
Journal:  Proc Natl Acad Sci U S A       Date:  2005-09-29       Impact factor: 11.205

4.  Converting stem cells to dendritic cells by agonist antibodies from unbiased morphogenic selections.

Authors:  Kyungmoo Yea; Hongkai Zhang; Jia Xie; Teresa M Jones; Guang Yang; Byeong Doo Song; Richard A Lerner
Journal:  Proc Natl Acad Sci U S A       Date:  2013-08-26       Impact factor: 11.205

5.  High affinity anti-inorganic material antibody generation by integrating graft and evolution technologies: potential of antibodies as biointerface molecules.

Authors:  Takamitsu Hattori; Mitsuo Umetsu; Takeshi Nakanishi; Takanari Togashi; Nozomi Yokoo; Hiroya Abe; Satoshi Ohara; Tadafumi Adschiri; Izumi Kumagai
Journal:  J Biol Chem       Date:  2009-12-31       Impact factor: 5.157

6.  High-affinity self-reactive human antibodies by design and selection: targeting the integrin ligand binding site.

Authors:  C F Barbas; L R Languino; J W Smith
Journal:  Proc Natl Acad Sci U S A       Date:  1993-11-01       Impact factor: 11.205

Review 7.  In vivo versus in vitro screening or selection for catalytic activity in enzymes and abzymes.

Authors:  J Fastrez
Journal:  Mol Biotechnol       Date:  1997-02       Impact factor: 2.695

8.  Tolerance of different proteins for amino acid diversity.

Authors:  M Suzuki; F C Christians; B Kim; A Skandalis; M E Black; L A Loeb
Journal:  Mol Divers       Date:  1996-10       Impact factor: 2.943

9.  A cofactor approach to copper-dependent catalytic antibodies.

Authors:  Kenneth M Nicholas; Paul Wentworth; Curtis W Harwig; Anita D Wentworth; Asher Shafton; Kim D Janda
Journal:  Proc Natl Acad Sci U S A       Date:  2002-03-05       Impact factor: 11.205

10.  Human autoantibody recognition of DNA.

Authors:  S M Barbas; H J Ditzel; E M Salonen; W P Yang; G J Silverman; D R Burton
Journal:  Proc Natl Acad Sci U S A       Date:  1995-03-28       Impact factor: 11.205
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.