Literature DB >> 8290342

Differences in the accessibility of methylated and unmethylated DNA to DNase I.

S Kochanek1, D Renz, W Doerfler.   

Abstract

DNase I binds in the minor groove of DNA and is used as an enzymatic tool to investigate the interaction of proteins with DNA. Here we show that the major groove located 5-methyldeoxycytidine can enhance or inhibit the cleavage rates of DNA by DNase I. This effect may be caused in part by changes in DNA structure affecting the accessibility of the minor groove of DNA to DNase I.

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Year:  1993        PMID： 8290342      PMCID： PMC310463          DOI： 10.1093/nar/21.25.5843

Source DB:  PubMed          Journal:  Nucleic Acids Res        ISSN： 0305-1048            Impact factor:   16.971


  16 in total

1.  Identification of a mammalian protein that binds specifically to DNA containing methylated CpGs.

Authors:  R R Meehan; J D Lewis; S McKay; E L Kleiner; A P Bird
Journal:  Cell       Date:  1989-08-11       Impact factor: 41.582

2.  The effect of HhaI methylation on DNA local structure.

Authors:  K R Fox
Journal:  Biochem J       Date:  1986-02-15       Impact factor: 3.857

3.  Structure of DNase I at 2.0 A resolution suggests a mechanism for binding to and cutting DNA.

Authors:  D Suck; C Oefner
Journal:  Nature       Date:  1986 Jun 5-11       Impact factor: 49.962

4.  DNA structural variations in the E. coli tyrT promoter.

Authors:  H R Drew; A A Travers
Journal:  Cell       Date:  1984-06       Impact factor: 41.582

Review 5.  DNA methylation and gene activity.

Authors:  W Doerfler
Journal:  Annu Rev Biochem       Date:  1983       Impact factor: 23.643

6.  Adenovirus type 2 VAI RNA transcription by polymerase III is blocked by sequence-specific methylation.

Authors:  R Jüttermann; K Hosokawa; S Kochanek; W Doerfler
Journal:  J Virol       Date:  1991-04       Impact factor: 5.103

7.  Cloning, characterization, and expression in Escherichia coli of the gene coding for the CpG DNA methylase from Spiroplasma sp. strain MQ1(M.SssI).

Authors:  P Renbaum; D Abrahamove; A Fainsod; G G Wilson; S Rottem; A Razin
Journal:  Nucleic Acids Res       Date:  1990-03-11       Impact factor: 16.971

8.  Sequence of the cDNA and gene for angiogenin, a human angiogenesis factor.

Authors:  K Kurachi; E W Davie; D J Strydom; J F Riordan; B L Vallee
Journal:  Biochemistry       Date:  1985-09-24       Impact factor: 3.162

9.  DNase I-induced DNA conformation. 2 A structure of a DNase I-octamer complex.

Authors:  A Lahm; D Suck
Journal:  J Mol Biol       Date:  1991-12-05       Impact factor: 5.469

10.  DNA methylation in the Alu sequences of diploid and haploid primary human cells.

Authors:  S Kochanek; D Renz; W Doerfler
Journal:  EMBO J       Date:  1993-03       Impact factor: 11.598
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  5 in total

1.  Probing DNA shape and methylation state on a genomic scale with DNase I.

Authors:  Allan Lazarovici; Tianyin Zhou; Anthony Shafer; Ana Carolina Dantas Machado; Todd R Riley; Richard Sandstrom; Peter J Sabo; Yan Lu; Remo Rohs; John A Stamatoyannopoulos; Harmen J Bussemaker
Journal:  Proc Natl Acad Sci U S A       Date:  2013-04-01       Impact factor: 11.205

2.  Light-regulated transcription of genes encoding peridinin chlorophyll a proteins and the major intrinsic light-harvesting complex proteins in the dinoflagellate amphidinium carterae hulburt (Dinophycae). Changes In cytosine methylation accompany photoadaptation

Authors: 
Journal:  Plant Physiol       Date:  1998-05       Impact factor: 8.340

3.  The topology of the promoter of RNA polymerase II- and III-transcribed genes is modified by the methylation of 5'-CG-3' dinucleotides.

Authors:  I Muiznieks; W Doerfler
Journal:  Nucleic Acids Res       Date:  1994-07-11       Impact factor: 16.971

4.  New Insights into Plant Extracellular DNA. A Study in Soybean Root Extracellular Trap.

Authors:  Marie Chambard; Carole Plasson; Céline Derambure; Sophie Coutant; Isabelle Tournier; Benjamin Lefranc; Jérôme Leprince; Marie-Christine Kiefer-Meyer; Azeddine Driouich; Marie-Laure Follet-Gueye; Isabelle Boulogne
Journal:  Cells       Date:  2021-01-05       Impact factor: 6.600

Review 5.  Role of Cell-Free DNA and Deoxyribonucleases in Tumor Progression.

Authors:  Ludmila Alekseeva; Nadezhda Mironova
Journal:  Int J Mol Sci       Date:  2021-11-12       Impact factor: 5.923
  5 in total

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