Literature DB >> 8254766

Investigation of the specificity of the herpes simplex virus type 1 protease by point mutagenesis of the autoproteolysis sites.

P J McCann1, D R O'Boyle, I C Deckman.   

Abstract

The herpes simplex virus type 1 (HSV-1) protease is cleaved at two autoprocessing sites during viral maturation, one of which shares amino acid identity with its substrate, ICP35. Similar autoprocessing sites have been observed within other members of the Herpesviridae. Introduction of point mutations within the autoprocessing sites of the HSV-1 protease indicated that specificity resides within the P4-P1' region of the cleavage sites.

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Year:  1994        PMID： 8254766      PMCID： PMC236316     

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  16 in total

1.  Identification of precursor to cytomegalovirus capsid assembly protein and evidence that processing results in loss of its carboxy-terminal end.

Authors:  W Gibson; A I Marcy; J C Comolli; J Lee
Journal:  J Virol       Date:  1990-03       Impact factor: 5.103

2.  Use of Ar+ plasma etching to localize structural proteins in the capsid of herpes simplex virus type 1.

Authors:  W W Newcomb; J C Brown
Journal:  J Virol       Date:  1989-11       Impact factor: 5.103

3.  Catalytic head assembling protein in virus morphogenesis.

Authors:  J King; S Casjens
Journal:  Nature       Date:  1974-09-13       Impact factor: 49.962

4.  Identification and characterization of a herpes simplex virus gene product required for encapsidation of virus DNA.

Authors:  V G Preston; J A Coates; F J Rixon
Journal:  J Virol       Date:  1983-03       Impact factor: 5.103

5.  Maturation of the head of bacteriophage T4. I. DNA packaging events.

Authors:  U K Laemmli; M Favre
Journal:  J Mol Biol       Date:  1973-11-15       Impact factor: 5.469

6.  Herpes simplex virus type 1 protease expressed in Escherichia coli exhibits autoprocessing and specific cleavage of the ICP35 assembly protein.

Authors:  I C Deckman; M Hagen; P J McCann
Journal:  J Virol       Date:  1992-12       Impact factor: 5.103

7.  Autoproteolysis of herpes simplex virus type 1 protease releases an active catalytic domain found in intermediate capsid particles.

Authors:  S P Weinheimer; P J McCann; D R O'Boyle; J T Stevens; B A Boyd; D A Drier; G A Yamanaka; C L DiIanni; I C Deckman; M G Cordingley
Journal:  J Virol       Date:  1993-10       Impact factor: 5.103

8.  Proteolysis of an active site peptide of lactate dehydrogenase by human immunodeficiency virus type 1 protease.

Authors:  T A Tomaszek; M L Moore; J E Strickler; R L Sanchez; J S Dixon; B W Metcalf; A Hassell; G B Dreyer; I Brooks; C Debouck
Journal:  Biochemistry       Date:  1992-10-27       Impact factor: 3.162

9.  Identification of the herpes simplex virus-1 protease cleavage sites by direct sequence analysis of autoproteolytic cleavage products.

Authors:  C L DiIanni; D A Drier; I C Deckman; P J McCann; F Liu; B Roizman; R J Colonno; M G Cordingley
Journal:  J Biol Chem       Date:  1993-01-25       Impact factor: 5.157

10.  Regulation of coat protein polymerization by the scaffolding protein of bacteriophage P22.

Authors:  M T Fuller; J King
Journal:  Biophys J       Date:  1980-10       Impact factor: 4.033
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  17 in total

1.  Packaging-competent capsids of a herpes simplex virus temperature-sensitive mutant have properties similar to those of in vitro-assembled procapsids.

Authors:  F J Rixon; D McNab
Journal:  J Virol       Date:  1999-07       Impact factor: 5.103

2.  Proline and tyrosine residues in scaffold proteins of herpes simplex virus 1 critical to the interaction with portal protein and its incorporation into capsids.

Authors:  Kui Yang; Joel D Baines
Journal:  J Virol       Date:  2009-05-27       Impact factor: 5.103

3.  Sequential autoprocessing of Marek's disease herpesvirus protease differs from that of other herpesviruses.

Authors:  S Laurent; C Blondeau; M Belghazi; S Remy; E Esnault; P Rasschaert; D Rasschaert
Journal:  J Virol       Date:  2007-03-21       Impact factor: 5.103

4.  The C-terminal 25 amino acids of the protease and its substrate ICP35 of herpes simplex virus type 1 are involved in the formation of sealed capsids.

Authors:  L Matusick-Kumar; W W Newcomb; J C Brown; P J McCann; W Hurlburt; S P Weinheimer; M Gao
Journal:  J Virol       Date:  1995-07       Impact factor: 5.103

5.  Proteolytic activity of human cytomegalovirus UL80 protease cleavage site mutants.

Authors:  T R Jones; L Sun; G A Bebernitz; V P Muzithras; H J Kim; S H Johnston; E Z Baum
Journal:  J Virol       Date:  1994-06       Impact factor: 5.103

6.  The protease of herpes simplex virus type 1 is essential for functional capsid formation and viral growth.

Authors:  M Gao; L Matusick-Kumar; W Hurlburt; S F DiTusa; W W Newcomb; J C Brown; P J McCann; I Deckman; R J Colonno
Journal:  J Virol       Date:  1994-06       Impact factor: 5.103

7.  Release of the catalytic domain N(o) from the herpes simplex virus type 1 protease is required for viral growth.

Authors:  L Matusick-Kumar; P J McCann; B J Robertson; W W Newcomb; J C Brown; M Gao
Journal:  J Virol       Date:  1995-11       Impact factor: 5.103

8.  3C-like protease of rabbit hemorrhagic disease virus: identification of cleavage sites in the ORF1 polyprotein and analysis of cleavage specificity.

Authors:  C Wirblich; M Sibilia; M B Boniotti; C Rossi; H J Thiel; G Meyers
Journal:  J Virol       Date:  1995-11       Impact factor: 5.103

9.  Cloning, expression and characterization of the proteinase from human herpesvirus 6.

Authors:  N J Tigue; P J Matharu; N A Roberts; J S Mills; J Kay; R Jupp
Journal:  J Virol       Date:  1996-06       Impact factor: 5.103

10.  Structural constraints on autoprocessing of the human nucleoporin Nup98.

Authors:  Yixin Sun; Hwai-Chen Guo
Journal:  Protein Sci       Date:  2008-03       Impact factor: 6.725
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