Age, gender, and tear break-up time.

We investigated the effect of age and gender on the tear break-up time (TBUT) of 2 groups of normal, asymptomatic subjects [92 Hong Kong-Chinese (HK-Chinese) and 76 Singapore-Chinese (S-Chinese)] using the conventional fluorescein-instillation technique. The mean TBUT (+/- SD) is 6.5 (+/- 4.0) s for the S-Chinese and 7.8 (+/- 2.4) s for the HK-Chinese. The mode was 7.0 s for HK-Chinese and 5.0 s for S-Chinese. About 80% of the subjects of each group have TBUT less than 10 s. The TBUT of both groups of Chinese decreases with age. It was found that TBUT was significantly different between the two sexes in the S-Chinese but no equivalent effect was observed in the HK-Chinese.