Literature DB >> 8234398

Recent evaluations of thiosemicarbazones and semicarbazones and related compounds for antineoplastic and anticonvulsant activities.

S N Pandeya1, J R Dimmock.   

Abstract

The antineoplastic activities of various carbocyclic, acylic and heterocyclic thiosemicarbazones as well as a number of semicarbazones are outlined. In addition, the anticonvulsant properties of a variety of cyclic and acyclic thiosemicarbazones and semicarbazones are discussed.

Entities:  

Mesh：

Substances：

Year:  1993        PMID： 8234398

Source DB:  PubMed          Journal:  Pharmazie        ISSN： 0031-7144            Impact factor:   1.267


  5 in total

1.  Selective toxicity of NSC73306 in MDR1-positive cells as a new strategy to circumvent multidrug resistance in cancer.

Authors:  Joseph A Ludwig; Gergely Szakács; Scott E Martin; Benjamin F Chu; Carol Cardarelli; Zuben E Sauna; Natasha J Caplen; Henry M Fales; Suresh V Ambudkar; John N Weinstein; Michael M Gottesman
Journal:  Cancer Res       Date:  2006-05-01       Impact factor: 12.701

2.  Evidence for dual mode of action of a thiosemicarbazone, NSC73306: a potent substrate of the multidrug resistance linked ABCG2 transporter.

Authors:  Chung-Pu Wu; Suneet Shukla; Anna Maria Calcagno; Matthew D Hall; Michael M Gottesman; Suresh V Ambudkar
Journal:  Mol Cancer Ther       Date:  2007-12       Impact factor: 6.261

3.  Molecular aspects on the interaction of isatin-3-isonicotinylhydrazone to deoxyribonucleic acid: model for intercalative drug-DNA binding.

Authors:  Soheila Kashanian; Mohammad Mehdi Khodaei; Parvaneh Pakravan; Hadi Adibi
Journal:  Mol Biol Rep       Date:  2011-07-21       Impact factor: 2.742

4.  (2E)-2-(4-Fluoro-benzyl-idene)hydrazinecarboxamide.

Authors:  Hoong-Kun Fun; Tze Shyang Chia; Shridhar Malladi; Arun M Isloor; Kammasandra N Shivananda
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2011-10-08

5.  2-Cyclo-pentyl-idenehydrazine-carboxamide.

Authors:  Hoong-Kun Fun; Wan-Sin Loh; Mahesh Padaki; Arun M Isloor; Nishitha A Isloor
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2012-08-11
  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.