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Literature DB >> 820250

Enzymatic modification of aminoglycoside antibiotics: a new 3-N-acetylating enzyme from a Pseudomonas aeruginosa isolate.

S Biddlecome, M Haas, J Davies, G H Miller, D F Rane, P J Daniels.

Abstract

A new 3-N-aminoglycoside acetyltransferase is described, which possesses a wider substrate range than any such enzyme so far discovered in clinical isolates of antibiotic-resistant bacteria.

Entities: Chemical Species

Mesh：

Substances：

Year: 1976 PMID： 820250 PMCID： PMC429656 DOI： 10.1128/AAC.9.6.951

Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN： 0066-4804 Impact factor: 5.191

7 in total

1. Letter: Gentamicin acetyltransferase in Escherichia coli carrying R factor.

Authors: H Umezawa; M Yagisawa; Y Matsuhashi; H Naganawa; H Yamamoto
Journal: J Antibiot (Tokyo) Date: 1973-10 Impact factor: 2.649

2. 3-N enzymatic acetylation of gentamicin, tobramycin, and kanamycin by Escherichia coli carrying an R factor.

Authors: F Le Goffic; A Martel; J Witchitz
Journal: Antimicrob Agents Chemother Date: 1974-12 Impact factor: 5.191

3. Enzymatic modification of aminoglycoside antibiotics: a new 6'-N-acetylating enzyme from a Pseudomonas aeruginosa isolate.

Authors: M Haas; S Biddlecome; J Davies; C E Luce; P J Daniels
Journal: Antimicrob Agents Chemother Date: 1976-06 Impact factor: 5.191

4. Purification and properties of gentamicin acetyltransferase I.

Authors: J W Williams; D B Northrop
Journal: Biochemistry Date: 1976-01-13 Impact factor: 3.162

5. Gentamicin resistance in strains of Pseudomonas aeruginosa mediated by enzymatic N-acetylation of the deoxystreptamine moiety.

Authors: M Brzezinska; R Benveniste; J Davies; P J Daniels; J Weinstein
Journal: Biochemistry Date: 1972-02-29 Impact factor: 3.162

6. Gentamicin antibiotics. 4. Some condensation products of gentamicin C2 with aromatic and aliphatic aldehydes.

Authors: D J Cooper; J Weinstein; J A Waitz
Journal: J Med Chem Date: 1971-11 Impact factor: 7.446

7. Bioconversion of ribostamycin (SF-733). II. Isolation and structure of 3-N-acetylribostamycin, a microbiologically inactive product of ribostamycin produced by Streptomyces ribosidificus.

Authors: M Kojima; N Ezaki; S Amano; S Inouye; T Nida
Journal: J Antibiot (Tokyo) Date: 1975-01 Impact factor: 2.649

7 in total

25 in total

1. Development of a DNA probe from the deoxyribonucleotide sequence of a 3-N-aminoglycoside acetyltransferase [AAC(3)-I] resistance gene.

Authors: F C Tenover; K L Phillips; T Gilbert; P Lockhart; P J O'Hara; J J Plorde
Journal: Antimicrob Agents Chemother Date: 1989-04 Impact factor: 5.191

Review 2. Aminoglycoside resistance in Pseudomonas aeruginosa.

Authors: Keith Poole
Journal: Antimicrob Agents Chemother Date: 2005-02 Impact factor: 5.191

3. Nucleotide sequence of the aacC3 gene, a gentamicin resistance determinant encoding aminoglycoside-(3)-N-acetyltransferase III expressed in Pseudomonas aeruginosa but not in Escherichia coli.

Authors: J S Vliegenthart; P A Ketelaar-van Gaalen; J A van de Klundert
Journal: Antimicrob Agents Chemother Date: 1991-05 Impact factor: 5.191

4. Nucleotide sequence of the aacC2 gene, a gentamicin resistance determinant involved in a hospital epidemic of multiply resistant members of the family Enterobacteriaceae.

Authors: J S Vliegenthart; P A Ketelaar-van Gaalen; J A van de Klundert
Journal: Antimicrob Agents Chemother Date: 1989-08 Impact factor: 5.191

5. Effect of aminoglycoside concentration on reaction rates of aminoglycoside-modifying enzymes.

Authors: G P Bongaerts; J S Vliegenthart
Journal: Antimicrob Agents Chemother Date: 1988-05 Impact factor: 5.191

6. Enzymatic modification of aminoglycoside antibiotics: 3-N-acetyltransferase with broad specificity that determines resistance to the novel aminoglycoside apramycin.

Authors: J Davies; S O'Connor
Journal: Antimicrob Agents Chemother Date: 1978-07 Impact factor: 5.191