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Literature DB >> 8188390

Diversity of the P2 protein among nontypeable Haemophilus influenzae isolates.

J Bell¹, S Grass, D Jeanteur, R S Munson.

Abstract

The genes for outer membrane protein P2 of four nontypeable Haemophilus influenzae strains were cloned and sequenced. The derived amino acid sequences were compared with the outer membrane protein P2 sequence from H. influenzae type b MinnA and the sequences of P2 from three additional nontypeable H. influenzae strains. The sequences were 76 to 94% identical. The sequences had regions with considerable variability separated by regions which were highly conserved. The variable regions mapped to putative surface-exposed loops of the protein.

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Year: 1994 PMID： 8188390 PMCID： PMC186559 DOI： 10.1128/iai.62.6.2639-2643.1994

Source DB: PubMed Journal: Infect Immun ISSN： 0019-9567 Impact factor: 3.441

32 in total

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Journal: Infect Immun Date: 1989-10 Impact factor: 3.441

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Journal: Mol Microbiol Date: 1989-12 Impact factor: 3.501

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Journal: Infect Immun Date: 1991-04 Impact factor: 3.441

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16 in total

1. Antibodies to loop 6 of the P2 porin protein of nontypeable Haemophilus influenzae are bactericidal against multiple strains.

Authors: J M Neary; K Yi; R J Karalus; T F Murphy
Journal: Infect Immun Date: 2001-02 Impact factor: 3.441

2. Characterization of a novel porin protein from Moraxella catarrhalis and identification of an immunodominant surface loop.

Authors: Donna M Easton; Adam Smith; Sara Gomez Gallego; A Ruth Foxwell; Allan W Cripps; Jennelle M Kyd
Journal: J Bacteriol Date: 2005-09 Impact factor: 3.490

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Journal: Infect Immun Date: 1997-04 Impact factor: 3.441

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Authors: S Sethi; T F Murphy
Journal: Clin Microbiol Rev Date: 2001-04 Impact factor: 26.132

7. Mutations in the lspA1 and lspA2 genes of Haemophilus ducreyi affect the virulence of this pathogen in an animal model system.

Authors: Christine K Ward; Jo L Latimer; Joseph Nika; Merja Vakevainen; Jason R Mock; Kaiping Deng; Robert J Blick; Eric J Hansen
Journal: Infect Immun Date: 2003-05 Impact factor: 3.441

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Authors: Stefania Galdiero; Domenica Capasso; Mariateresa Vitiello; Marina D'Isanto; Carlo Pedone; Massimiliano Galdiero
Journal: Infect Immun Date: 2003-05 Impact factor: 3.441

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Authors: G R Bolduc; V Bouchet; R Z Jiang; J Geisselsoder; Q C Truong-Bolduc; P A Rice; S I Pelton; R Goldstein
Journal: Infect Immun Date: 2000-08 Impact factor: 3.441

10. Mucosal immunization of mice with recombinant OMP P2 induces antibodies that bind to surface epitopes of multiple strains of nontypeable Haemophilus influenzae.

Authors: K L Ostberg; M W Russell; T F Murphy
Journal: Mucosal Immunol Date: 2008-10-29 Impact factor: 7.313