Literature DB >> 817928

4-Isothiocyanato-4'-nitrodiphenylamine (C 9333-Go/CGP 4540), an anthelminthic with an unusual spectrum of activity against intestinal nematodes, filariae and schistosomes.

H P Striebel.   

Abstract

4-isothiocyanato-4'-nitrodiphenylamine was found to possess activity against intestinal nematodes in mice, against schistosomes in various hosts including primates and against two filarial species in the mongolian jird. Upon administration in a single oral dose it is equally effective against S. haematobium, S. mansoni and S. japonicum.

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Year:  1976        PMID: 817928     DOI: 10.1007/BF01920794

Source DB:  PubMed          Journal:  Experientia        ISSN: 0014-4754


  5 in total

1.  [EXPERIMENTAL CHEMOTHERAPY OF TREMATODE INFECTIONS AND ITS PROBLEMS. 3. CHEMOTHERAPEUTIC STUDIES ON ANIMALS EXPERIMENTALLY INFECTED WITH SCHISTOSOMA MANSONI].

Authors:  G LAEMMLER
Journal:  Z Tropenmed Parasitol       Date:  1964-10

2.  Antischistosomal and some toxicological properties of a nitrodiphenylaminoisothiocyanate (C 9333-Go/CGP 4540).

Authors:  E Bueding; R Batzinger; G Petterson
Journal:  Experientia       Date:  1976-05-15

3.  Studies with the schistosomicide oxamniquine (UK-4271). I. Activity in rodents and in vitro.

Authors:  R Foster; B L Cheetham
Journal:  Trans R Soc Trop Med Hyg       Date:  1973       Impact factor: 2.184

4.  Studies with the schistosomicide oxamniquine (UK-4271). II. Activity in primates.

Authors:  R Foster; B L Cheetham; D F King
Journal:  Trans R Soc Trop Med Hyg       Date:  1973       Impact factor: 2.184

5.  The effects of niridazole in experimental schistosomiasis.

Authors:  H P Striebel
Journal:  Ann N Y Acad Sci       Date:  1969-10-06       Impact factor: 5.691

  5 in total
  7 in total

Review 1.  Schistosomiasis--a century searching for chemotherapeutic drugs.

Authors:  Gabriela Ribeiro-dos-Santos; Sergio Verjovski-Almeida; Luciana C C Leite
Journal:  Parasitol Res       Date:  2006-04-25       Impact factor: 2.289

2.  Antischistosomal and some toxicological properties of a nitrodiphenylaminoisothiocyanate (C 9333-Go/CGP 4540).

Authors:  E Bueding; R Batzinger; G Petterson
Journal:  Experientia       Date:  1976-05-15

3.  Phase 1 tolerability and searching dose studies with 4-isothiocyanato-4'-nitrodiphenylamine (C.9333-Go/CGP 4540), a new anthelmintic.

Authors:  A B Vaidya; H G Sen; N A Mankodi; T Paul; U K Sheth
Journal:  Br J Clin Pharmacol       Date:  1977-08       Impact factor: 4.335

Review 4.  Schistosomiasis drug therapy and treatment considerations.

Authors:  K C Shekhar
Journal:  Drugs       Date:  1991-09       Impact factor: 9.546

Review 5.  Clinical pharmacokinetics of anthelmintic drugs.

Authors:  G Edwards; A M Breckenridge
Journal:  Clin Pharmacokinet       Date:  1988-08       Impact factor: 6.447

6.  Antischistosomal effects of cyclosporin A.

Authors:  E Bueding; J Hawkins; Y N Cha
Journal:  Agents Actions       Date:  1981-07

7.  Chemotherapeutic effects of 4-isothiocyanato-4'-nitrodiphenylamine (C9333-Go/CGP 4540) on infections with Nematospiroides dubius, Hymenolepis diminuta, Hymenolepis nana and Spirometra mansonoides.

Authors:  K R Middleton; F W Schaefer; H J Saz
Journal:  Experientia       Date:  1979-02-15
  7 in total

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