Literature DB >> 8168847

A transcribed polymorphism and sub-localisation of MDM2.

J Heighway1, E L Mitchell, D Jones, G R White, M F Santibáñez Koref.   

Abstract

An NlaIV polymorphism in the 5' untranslated region of the MDM2 gene is described. MDM2 was sublocalised by fluorescence in situ hybridisation with a yeast artificial chromosome probe to 12q14.3-12q15. We demonstrate the use of the polymorphism to assess allelic imbalance in breast tumours.

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Year:  1994        PMID： 8168847     DOI： 10.1007/bf00202837

Source DB:  PubMed          Journal:  Hum Genet        ISSN： 0340-6717            Impact factor:   4.132


  12 in total

1.  1p13 is the most frequently involved band in structural chromosomal rearrangements in human breast cancer.

Authors:  E L Mitchell; M F Santibanez-Koref
Journal:  Genes Chromosomes Cancer       Date:  1990-11       Impact factor: 5.006

2.  Generation and fluorescent in situ hybridization mapping of yeast artificial chromosomes of 1p, 17p, 17q, and 19q from a hybrid cell line by high-density screening of an amplified library.

Authors:  M S Driesen; J G Dauwerse; M C Wapenaar; E J Meershoek; P Mollevanger; K L Chen; K H Fischbeck; G J van Ommen
Journal:  Genomics       Date:  1991-12       Impact factor: 5.736

3.  High-resolution mapping of human chromosome 11 by in situ hybridization with cosmid clones.

Authors:  P Lichter; C J Tang; K Call; G Hermanson; G A Evans; D Housman; D C Ward
Journal:  Science       Date:  1990-01-05       Impact factor: 47.728

4.  A 3.5 genome equivalent multi access YAC library: construction, characterisation, screening and storage.

Authors:  R Anand; J H Riley; R Butler; J C Smith; A F Markham
Journal:  Nucleic Acids Res       Date:  1990-04-25       Impact factor: 16.971

5.  p53 germline mutations in Li-Fraumeni syndrome.

Authors:  M F Santibáñez-Koref; J M Birch; A L Hartley; P H Jones; A W Craft; T Eden; D Crowther; A M Kelsey; M Harris
Journal:  Lancet       Date:  1991-12-14       Impact factor: 79.321

6.  A polymerase chain reaction-based method for the detection of trisomy 12 in B chronic lymphocytic leukaemia.

Authors:  B W Baker; J Heighway; P J Browett; J D Norton
Journal:  Br J Haematol       Date:  1993-09       Impact factor: 6.998

7.  Amplification of a gene encoding a p53-associated protein in human sarcomas.

Authors:  J D Oliner; K W Kinzler; P S Meltzer; D L George; B Vogelstein
Journal:  Nature       Date:  1992-07-02       Impact factor: 49.962

8.  Abnormal expression of wild type p53 protein in normal cells of a cancer family patient.

Authors:  D M Barnes; A M Hanby; C E Gillett; S Mohammed; S Hodgson; L G Bobrow; I M Leigh; T Purkis; C MacGeoch; N K Spurr
Journal:  Lancet       Date:  1992-08-01       Impact factor: 79.321

Review 9.  p53 mutations in human cancers.

Authors:  M Hollstein; D Sidransky; B Vogelstein; C C Harris
Journal:  Science       Date:  1991-07-05       Impact factor: 47.728

10.  The mdm-2 oncogene can overcome wild-type p53 suppression of transformed cell growth.

Authors:  C A Finlay
Journal:  Mol Cell Biol       Date:  1993-01       Impact factor: 4.272
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  3 in total

1.  YAC clones that extend the human chromosome 12cen-12q15 region contig map.

Authors:  S E Andersen; N J Lench; A F Markham
Journal:  Mamm Genome       Date:  1996-10       Impact factor: 2.957

2.  Mapping of gene loci in the Q13-Q15 region of chromosome 12.

Authors:  E L Mitchell; G R White; M F Santibanez-Koref; J M Varley; J Heighway
Journal:  Chromosome Res       Date:  1995-06       Impact factor: 5.239

3.  Linkage studies in a Li-Fraumeni family with increased expression of p53 protein but no germline mutation in p53.

Authors:  J M Birch; J Heighway; M D Teare; A M Kelsey; A L Hartley; K J Tricker; D Crowther; D P Lane; M F Santibáñez-Koref
Journal:  Br J Cancer       Date:  1994-12       Impact factor: 7.640
  3 in total

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