Literature DB >> 8146660

Stimulation of human gamma delta T cells by nonpeptidic mycobacterial ligands.

P Constant1, F Davodeau, M A Peyrat, Y Poquet, G Puzo, M Bonneville, J J Fournié.   

Abstract

Most human peripheral blood gamma delta T lymphocytes respond to hitherto unidentified mycobacterial antigens. Four ligands from Mycobacterium tuberculosis strain H37Rv that stimulated proliferation of a major human gamma delta T cell subset were isolated and partially characterized. One of these ligands, TUBag4, is a 5' triphosphorylated thymidine-containing compound, to which the three other stimulatory molecules are structurally related. These findings support the hypothesis that some gamma delta T cells recognize nonpeptidic ligands.

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Year:  1994        PMID： 8146660     DOI： 10.1126/science.8146660

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  206 in total

1.  The proportion of circulating gammadelta T cells increases after the first week of onset of tularaemia and remains elevated for more than a year.

Authors:  M Kroca; A Tärnvik; A Sjöstedt
Journal:  Clin Exp Immunol       Date:  2000-05       Impact factor: 4.330

Review 2.  A role for epithelial gammadelta T cells in tissue repair.

Authors:  W L Havran
Journal:  Immunol Res       Date:  2000       Impact factor: 2.829

3.  Identification of distinct lymphocyte subsets responding to subcellular fractions of Mycobacterium bovis bacille calmette-Guérin (BCG).

Authors:  G Batoni; S Esin; M Pardini; D Bottai; S Senesi; H Wigzell; M Campa
Journal:  Clin Exp Immunol       Date:  2000-02       Impact factor: 4.330

Review 4.  Human gamma delta T lymphocytes in HIV disease: effector functions and control by natural killer cell receptors.

Authors:  M L Gougeon; F Poccia; S Boullier
Journal:  Springer Semin Immunopathol       Date:  2000

Review 5.  Tissue distribution, antigen specificity and effector functions of gamma delta T cells in human diseases.

Authors:  G De Libero
Journal:  Springer Semin Immunopathol       Date:  2000

Review 6.  Antigen recognition by human gamma delta T cells: pattern recognition by the adaptive immune system.

Authors:  C T Morita; R A Mariuzza; M B Brenner
Journal:  Springer Semin Immunopathol       Date:  2000

Review 7.  Metabolic routes as targets for immunological discrimination of host and parasite.

Authors:  H Sicard; J J Fournie
Journal:  Infect Immun       Date:  2000-08       Impact factor: 3.441

8.  Granule-dependent cytolysis of Mycobacterium tuberculosis-infected macrophages by human gammadelta+ T cells has no effect on intracellular mycobacterial viability.

Authors:  J S Passmore; R H Glashoff; P T Lukey; S R Ress
Journal:  Clin Exp Immunol       Date:  2001-10       Impact factor: 4.330

9.  Adaptive immune response of Vgamma2Vdelta2+ T cells during mycobacterial infections.

Authors:  Yun Shen; Dejiang Zhou; Liyou Qiu; Xioamin Lai; Meredith Simon; Ling Shen; Zhongchen Kou; Qifan Wang; Liming Jiang; Jim Estep; Robert Hunt; Michelle Clagett; Prabhat K Sehgal; Yunyaun Li; Xuejun Zeng; Craig T Morita; Michael B Brenner; Norman L Letvin; Zheng W Chen
Journal:  Science       Date:  2002-03-22       Impact factor: 47.728

10.  Tumor-infiltrating γδ T lymphocytes predict clinical outcome in human breast cancer.

Authors:  Chunling Ma; Qunyuan Zhang; Jian Ye; Fang Wang; Yanping Zhang; Eric Wevers; Theresa Schwartz; Pamela Hunborg; Mark A Varvares; Daniel F Hoft; Eddy C Hsueh; Guangyong Peng
Journal:  J Immunol       Date:  2012-10-03       Impact factor: 5.422
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