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Literature DB >> 10852103

A role for epithelial gammadelta T cells in tissue repair.

Abstract

My colleagues and I have a long-term interest in interactions between intraepithelial gammadelta T cells and neighboring epithelial cells. We have focused our studies on interactions in the thymus, skin, and intestine, and are investigating the development, specificity, and function of these gammadelta T cells. Our results have defined unique properties of these cells and support a specialized role for epithelial gammadelta T cells in immune surveillance, wound repair, inflammation, and protection from malignancy.

Entities: Disease

Mesh：

Substances：

Year: 2000 PMID： 10852103 DOI： 10.1385/IR:21:2-3:63

Source DB: PubMed Journal: Immunol Res ISSN： 0257-277X Impact factor: 2.829

50 in total

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Journal: J Immunol Date: 1994-10-01 Impact factor: 5.422

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14 in total

Review 1. Mechanisms of immune resolution.

Authors: Alfred Ayala; Chun-Shiang Chung; Patricia S Grutkoski; Grace Y Song
Journal: Crit Care Med Date: 2003-08 Impact factor: 7.598

2. gamma delta T cells are necessary for platelet and neutrophil accumulation in limbal vessels and efficient epithelial repair after corneal abrasion.

Authors: Zhijie Li; Alan R Burns; Rolando E Rumbaut; C Wayne Smith
Journal: Am J Pathol Date: 2007-08-03 Impact factor: 4.307

3. Differential roles of IL-2-inducible T cell kinase-mediated TCR signals in tissue-specific localization and maintenance of skin intraepithelial T cells.

Authors: Mingcan Xia; Qian Qi; Yan Jin; David L Wiest; Avery August; Na Xiong
Journal: J Immunol Date: 2010-05-17 Impact factor: 5.422

4. Dendritic epidermal T cells regulate skin antimicrobial barrier function.

Authors: Amanda S MacLeod; Saskia Hemmers; Olivia Garijo; Marianne Chabod; Kerri Mowen; Deborah A Witherden; Wendy L Havran
Journal: J Clin Invest Date: 2013-09-24 Impact factor: 14.808

5. Osteonecrosis of the Jaw Developed in Mice: DISEASE VARIANTS REGULATED BY γδ T CELLS IN ORAL MUCOSAL BARRIER IMMUNITY.

Authors: Sil Park; Keiichi Kanayama; Kawaljit Kaur; Han-Ching Helen Tseng; Sina Banankhah; Davood Talebi Quje; James W Sayre; Anahid Jewett; Ichiro Nishimura
Journal: J Biol Chem Date: 2015-05-26 Impact factor: 5.157

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Authors: Martin G Schwacha
Journal: Burns Date: 2008-10-31 Impact factor: 2.744

7. Programmed downregulation of CCR6 is important for establishment of epidermal γδT cells by regulating their thymic egress and epidermal location.

Authors: Shaomin Hu; Na Xiong
Journal: J Immunol Date: 2013-02-18 Impact factor: 5.422