Literature DB >> 813220

Similarities among hypervariable segments of immunoglobulin chains.

T T Wu, E A Kabat, H Bilofsky.   

Abstract

A human lambdaV (Mcg) and a human lambdaII (Vil) myeloma protein have identical sequences in their first hypervariable segments although they differ at 21 positions throughout the variable region. If a different structural gene is responsible for each subgroup, the findings favor insertion of information for the hypervariable or complementarity-determining segments.

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Year:  1975        PMID： 813220      PMCID： PMC388885          DOI： 10.1073/pnas.72.12.5107

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  30 in total

1.  The PROPHET system and resource sharing.

Authors:  W F Raub
Journal:  Fed Proc       Date:  1974-12

2.  Amino acid sequence similarities in two human anti gamma globulin antibodies.

Authors:  J D Capra; H G Kunkel
Journal:  Proc Natl Acad Sci U S A       Date:  1970-09       Impact factor: 11.205

3.  Variability in the lambda light chain sequences of mouse antibody.

Authors:  M G Weigert; I M Cesari; S J Yonkovich; M Cohn
Journal:  Nature       Date:  1970-12-12       Impact factor: 49.962

4.  Hypervariable regions, idiotypy, and the antibody-combining site.

Authors:  J D Capra; J M Kehoe
Journal:  Adv Immunol       Date:  1975       Impact factor: 3.543

5.  Variable region sequence of the heavy chain from a phosphorylcholine binding myeloma protein.

Authors:  S Rudikoff; M Potter
Journal:  Biochemistry       Date:  1974-09-10       Impact factor: 3.162

Review 6.  Affinity labeling and topology of the antibody combining site.

Authors:  D Givol
Journal:  Essays Biochem       Date:  1974       Impact factor: 8.000

7.  Structure of antibodies with shared idiotypy: the complete sequence of the heavy chain variable regions of two immunoglobulin M anti-gamma globulins.

Authors:  J D Capra; J M Kehoe
Journal:  Proc Natl Acad Sci U S A       Date:  1974-10       Impact factor: 11.205

8.  Immunoglobulin structure: amino terminal sequences of mouse myeloma proteins that bind phosphorylcholine.

Authors:  P Barstad; S Rudikoff; M Potter; M Cohn; W Konigsberg; L Hood
Journal:  Science       Date:  1974-03-08       Impact factor: 47.728

9.  Structural studies on induced antibodies with defined idiotypic specificities. I. The heavy chains of anti-p-azophenylarsonate antibodies from A/J mice bearing a cross-reactive idiotype.

Authors:  J D Capra; A S Tung; A Nisonoff
Journal:  J Immunol       Date:  1975-05       Impact factor: 5.422

10.  The three-dimensional structure of the fab' fragment of a human myeloma immunoglobulin at 2.0-angstrom resolution.

Authors:  R J Poljak; L M Amzel; B L Chen; R P Phizackerley; F Saul
Journal:  Proc Natl Acad Sci U S A       Date:  1974-09       Impact factor: 11.205
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  5 in total

1.  Sequence of a mouse germ-line gene for a variable region of an immunoglobulin light chain.

Authors:  S Tonegawa; A M Maxam; R Tizard; O Bernard; W Gilbert
Journal:  Proc Natl Acad Sci U S A       Date:  1978-03       Impact factor: 11.205

2.  Some correlations between specificity and sequence of the first complementarity-determining segments of human kappa light chains.

Authors:  E A Kabat; T T Wu; H Bilofsky
Journal:  Proc Natl Acad Sci U S A       Date:  1976-12       Impact factor: 11.205

3.  Variable region genes for the immunoglobulin framework are assembled from small segments of DNA--a hypothesis.

Authors:  E A Kabat; T T Wu; H Bilofsky
Journal:  Proc Natl Acad Sci U S A       Date:  1978-05       Impact factor: 11.205

4.  Human and murine phosphorycholine-binding immunoglobulins: conserved subgroup and first hypervariable region of heavy chains.

Authors:  W F Riesen; D G Braun; J C Jaton
Journal:  Proc Natl Acad Sci U S A       Date:  1976-06       Impact factor: 11.205

5.  Complete amino acid sequence of heavy chain variable regions derived from two monoclonal anti-p-azophenylarsonate antibodies of BALB/c mice expressing the major cross-reactive idiotype of the A/J strain.

Authors:  K Meek; D Jeske; M Slaoui; O Leo; J Urbain; J D Capra
Journal:  J Exp Med       Date:  1984-10-01       Impact factor: 14.307
  5 in total

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