Literature DB >> 4195825

Amino acid sequence similarities in two human anti gamma globulin antibodies.

J D Capra, H G Kunkel.   

Abstract

Certain individuals with hypergammaglobulinemic purpura contain in their serum anti gamma globulins of restricted heterogeneity. These antibodies, characteristically of the gammaG type, were isolated from two unrelated individuals and their light polypeptide chains were subjected to amino acid sequence analysis. Although these anti gamma globulin antibodies conform to the basic VK(1) sequence, substitutions not previously encountered were found in five positions. The two antibodies were identical with each other up to residue 40 from the N-terminus of the light chains.

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Year:  1970        PMID: 4195825      PMCID: PMC283171          DOI: 10.1073/pnas.67.1.87

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN: 0027-8424            Impact factor:   11.205


  19 in total

1.  Two structurally distinct classes of kappa-chains in human immunoglobulins.

Authors:  H D Niall; P Edman
Journal:  Nature       Date:  1967-10-21       Impact factor: 49.962

2.  Linked groups of residues in immunoglobulin k chains.

Authors:  C Milstein
Journal:  Nature       Date:  1967-10-28       Impact factor: 49.962

3.  Mechanism of antibody synthesis: size differences between mouse kappa chains.

Authors:  W R Gray; W J Dreyer; L Hood
Journal:  Science       Date:  1967-01-27       Impact factor: 47.728

Review 4.  The nature of an antigenic determinant.

Authors:  E A Kabat
Journal:  J Immunol       Date:  1966-07       Impact factor: 5.422

5.  Amino acid sequence studies with Bence-Jones proteins.

Authors:  N Hilschmann; L C Craig
Journal:  Proc Natl Acad Sci U S A       Date:  1965-06       Impact factor: 11.205

6.  Immunoglobulin structure: partial amino acid sequence of a Bence Jones protein.

Authors:  K Titani; E Whitley; L Avogardo; F W Putnam
Journal:  Science       Date:  1965-09-03       Impact factor: 47.728

7.  Hydrolysis of phenylthiohydantoins of amino acids.

Authors:  H O Van Orden; F H Carpenter
Journal:  Biochem Biophys Res Commun       Date:  1964       Impact factor: 3.575

8.  A protein sequenator.

Authors:  P Edman; G Begg
Journal:  Eur J Biochem       Date:  1967-03

9.  Variations in amino-acid sequence near the disulphide bridges of Bence-Jones proteins.

Authors:  C Milstein
Journal:  Nature       Date:  1966-01-22       Impact factor: 49.962

10.  Studies on human antibodies. VI. Selective variations in subgroup composition and genetic markers.

Authors:  W J Yount; M M Dorner; H G Kunkel; E A Kabat
Journal:  J Exp Med       Date:  1968-03-01       Impact factor: 14.307

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  13 in total

1.  The partial amino-acid sequence of an H-2K molecule.

Authors:  E S Vitetta; J D Capra; D G Klapper; J Klein; J W Uhr
Journal:  Proc Natl Acad Sci U S A       Date:  1976-03       Impact factor: 11.205

2.  Variable region sequences of five human immunoglobulin heavy chains of the VH3 subgroup: definitive identification of four heavy chain hypervariable regions.

Authors:  J D Capra; J M Kehoe
Journal:  Proc Natl Acad Sci U S A       Date:  1974-03       Impact factor: 11.205

3.  Localization of two additional hypervariable regions in immunoglobulin heavy chains.

Authors:  J M Kehoe; J D Capra
Journal:  Proc Natl Acad Sci U S A       Date:  1971-09       Impact factor: 11.205

Review 4.  Molecular basis for cryoprecipitation.

Authors:  A C Wang
Journal:  Springer Semin Immunopathol       Date:  1988

Review 5.  Cross-reacting idiotypes on cryoprecipitating rheumatoid factor.

Authors:  P P Chen; S Fong; F Goni; G J Silverman; R I Fox; M F Liu; B Frangione; D A Carson
Journal:  Springer Semin Immunopathol       Date:  1988

6.  Similarities among hypervariable segments of immunoglobulin chains.

Authors:  T T Wu; E A Kabat; H Bilofsky
Journal:  Proc Natl Acad Sci U S A       Date:  1975-12       Impact factor: 11.205

Review 7.  Genetic determination of antibody specificity. Gene translocation and fusion, the molecular basis for the differentiation of the antibody-producing cell.

Authors:  N Hilschmann; H U Barnikol; H Kratzin; P Altevogt; M Engelhard; S Barnikol-Watanabe
Journal:  Naturwissenschaften       Date:  1978-12

Review 8.  [Immune response with monoclonal differentiation].

Authors:  D G Braun
Journal:  Klin Wochenschr       Date:  1971-12-01

9.  Evolution of neurophysin proteins: the partial sequence of bovine neurophysin-I (vasopressin-oxytocin-carrier proteins-automated amino-acid-sequence analysis-homology-protein evolution).

Authors:  J D Capra; J M Kehoe; D Kotelchuck; R Walter; E Breslow
Journal:  Proc Natl Acad Sci U S A       Date:  1972-02       Impact factor: 11.205

10.  Human and murine phosphorycholine-binding immunoglobulins: conserved subgroup and first hypervariable region of heavy chains.

Authors:  W F Riesen; D G Braun; J C Jaton
Journal:  Proc Natl Acad Sci U S A       Date:  1976-06       Impact factor: 11.205

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