Literature DB >> 811576

Effects of irradiation on saliva in cancer patients.

H Ben-Aryeh, D Gutman, R Szargel, D Laufer.   

Abstract

Whole unstimulated saliva was analyzed in 15 healthy individuals and 15 patients with malignant tumors in the head and neck region before and during irradiation therapy. Flow rate, pH, electrolytes (Na, K, Ca, Mg), protein and phosphate were measured. There was a decrease in rate of flow, and pH changed towards acidity. The most significant finding was the increased sodium content. We believe that irradiation reduces the reabsorption ability of the tubuli, causing the sodium content of the saliva to increase.

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Year:  1975        PMID: 811576     DOI: 10.1016/s0300-9785(75)80027-5

Source DB:  PubMed          Journal:  Int J Oral Surg        ISSN: 0300-9785


  12 in total

1.  Does irradiation affect the protein composition of saliva?

Authors:  M Hannig; E Dounis; T Henning; N Apitz; L Stösser
Journal:  Clin Oral Investig       Date:  2006-02-01       Impact factor: 3.573

2.  Anti-caries effect of CPP-ACP in irradiated nasopharyngeal carcinoma patients.

Authors:  Christina P C Sim; Joseph Wee; Ying Xu; Yin-Bun Cheung; Yoke-Lim Soong; David J Manton
Journal:  Clin Oral Investig       Date:  2014-09-27       Impact factor: 3.573

3.  Effects of radiotherapy on parotid salivary sialochemistry in head and neck cancer patients.

Authors:  S C Gupta; Alok Singla; Mangal Singh; B Paul Thaliath; Jaiswal Geeta
Journal:  Indian J Otolaryngol Head Neck Surg       Date:  2010-01-09

Review 4.  [Radiation-related caries: etiology and possible preventive strategies. What should the radiotherapist know?].

Authors:  R Schweyen; J Hey; W Fränzel; D Vordermark; G Hildebrandt; T Kuhnt
Journal:  Strahlenther Onkol       Date:  2011-12-23       Impact factor: 3.621

5.  Histopathological study of the human submandibular gland in graft versus host disease.

Authors:  R M Nagler; Y Sherman; A Nagler
Journal:  J Clin Pathol       Date:  1999-05       Impact factor: 3.411

6.  Analysis of factors influencing the development of xerostomia during intensity-modulated radiotherapy.

Authors:  Ken Randall; Jason Stevens; Juan Fernando Yepes; Marcus E Randall; Mahesh Kudrimoti; Jonathan Feddock; Jing Xi; Richard J Kryscio; Craig S Miller
Journal:  Oral Surg Oral Med Oral Pathol Oral Radiol       Date:  2013-03-22

Review 7.  Xerostomia induced by radiotherapy: an overview of the physiopathology, clinical evidence, and management of the oral damage.

Authors:  Roberto Pinna; Guglielmo Campus; Enzo Cumbo; Ida Mura; Egle Milia
Journal:  Ther Clin Risk Manag       Date:  2015-02-04       Impact factor: 2.423

8.  Investigation of salivary function and oral microbiota of radiation caries-free people with nasopharyngeal carcinoma.

Authors:  Jingyang Zhang; Hongling Liu; Xue Liang; Min Zhang; Renke Wang; Guang Peng; Jiyao Li
Journal:  PLoS One       Date:  2015-04-10       Impact factor: 3.240

9.  The effect of parotid gland-sparing intensity-modulated radiotherapy on salivary composition, flow rate and xerostomia measures.

Authors:  T M Richards; T Hurley; L Grove; K J Harrington; G H Carpenter; G B Proctor; C M Nutting
Journal:  Oral Dis       Date:  2017-06-05       Impact factor: 3.511

10.  Salivary Anionic Changes after Radiotherapy for Nasopharyngeal Carcinoma: A 1-Year Prospective Study.

Authors:  Edmond H N Pow; Zhuofan Chen; Dora L W Kwong; Otto L T Lam
Journal:  PLoS One       Date:  2016-03-31       Impact factor: 3.240

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