Literature DB >> 8076941

A long range restriction map spanning the myxoid liposarcoma breakpoint in the q13-14 region of human chromosome 12.

A Forus1, P F Kools, E F Schoenmakers, W J Van de Ven, O Myklebost.   

Abstract

We have used pulsed-field gel electrophoresis to construct a long range restriction map of the myxoid liposarcoma (MLS) breakpoint region in 12q13-14. The CHOP/GADD153 gene, consistently translocated in myxoid liposarcomas, is located less than 55 kb from the putative oncogene GLI. We have used fluorescent in situ hybridization to orient the map with respect to the chromosome, and to show that GLI (and thus A2MR) is located proximal to the MLS breakpoint.

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Year:  1994        PMID： 8076941     DOI： 10.1007/bf00208280

Source DB:  PubMed          Journal:  Hum Genet        ISSN： 0340-6717            Impact factor:   4.132


  29 in total

1.  Rapid subchromosomal localization of cosmids by nonradioactive in situ hybridization.

Authors:  T Kievits; J G Dauwerse; J Wiegant; P Devilee; M H Breuning; C J Cornelisse; G J van Ommen; P L Pearson
Journal:  Cytogenet Cell Genet       Date:  1990

2.  Rearrangements of chromosome region 12q13----q15 in pleomorphic adenomas of the human salivary gland (PSA).

Authors:  J Bullerdiek; S Bartnitzke; M Weinberg; R Chilla; J Haubrich; W Schloot
Journal:  Cytogenet Cell Genet       Date:  1987

3.  DNA damage-inducible transcripts in mammalian cells.

Authors:  A J Fornace; I Alamo; M C Hollander
Journal:  Proc Natl Acad Sci U S A       Date:  1988-12       Impact factor: 11.205

4.  Regional mapping of the human NSP gene to chromosome region 14q21-->q22 by fluorescence in situ hybridization analysis.

Authors:  P F Kools; A J Roebroek; H J Van de Velde; P Marynen; J Bullerdiek; W J Van de Ven
Journal:  Cytogenet Cell Genet       Date:  1994

5.  Amplification of a gene encoding a p53-associated protein in human sarcomas.

Authors:  J D Oliner; K W Kinzler; P S Meltzer; D L George; B Vogelstein
Journal:  Nature       Date:  1992-07-02       Impact factor: 49.962

6.  The characterization of high-resolution G-banded chromosomes of man.

Authors:  J J Yunis; J R Sawyer; D W Ball
Journal:  Chromosoma       Date:  1978-08-14       Impact factor: 4.316

7.  MDM2 gene amplification in metastatic osteosarcoma.

Authors:  M Ladanyi; C Cha; R Lewis; S C Jhanwar; A G Huvos; J H Healey
Journal:  Cancer Res       Date:  1993-01-01       Impact factor: 12.701

8.  The protooncogene CHOP/GADD153, involved in growth arrest and DNA damage response, is amplified in a subset of human sarcomas.

Authors:  A Forus; V A Flørenes; G M Maelandsmo; O Fodstad; O Myklebost
Journal:  Cancer Genet Cytogenet       Date:  1994-12

9.  Rearrangement of the transcription factor gene CHOP in myxoid liposarcomas with t(12;16)(q13;p11).

Authors:  P Aman; D Ron; N Mandahl; T Fioretos; S Heim; K Arheden; H Willén; A Rydholm; F Mitelman
Journal:  Genes Chromosomes Cancer       Date:  1992-11       Impact factor: 5.006

10.  The GLI gene is a member of the Kruppel family of zinc finger proteins.

Authors:  K W Kinzler; J M Ruppert; S H Bigner; B Vogelstein
Journal:  Nature       Date:  1988-03-24       Impact factor: 49.962
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