Literature DB >> 8275708

Regional mapping of the human NSP gene to chromosome region 14q21-->q22 by fluorescence in situ hybridization analysis.

P F Kools1, A J Roebroek, H J Van de Velde, P Marynen, J Bullerdiek, W J Van de Ven.   

Abstract

Genetic sequences of the novel NSP gene, which encodes neuroendocrine-specific proteins, were isolated from cDNA libraries constructed with mRNA isolated from human lung carcinoma cells. Hybridization analysis of a panel of human x mouse cell hybrids with an 0.8-kb NSP cDNA probe indicated that the human NSP gene is probably located on chromosome 14. Fluorescence in situ hybridization analysis of metaphase chromosomes using overlapping genomic clones of NSP as a probe localized the NSP gene to chromosome region 14q21-->q22.

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Year:  1994        PMID: 8275708     DOI: 10.1159/000133662

Source DB:  PubMed          Journal:  Cytogenet Cell Genet        ISSN: 0301-0171


  1 in total

1.  A long range restriction map spanning the myxoid liposarcoma breakpoint in the q13-14 region of human chromosome 12.

Authors:  A Forus; P F Kools; E F Schoenmakers; W J Van de Ven; O Myklebost
Journal:  Hum Genet       Date:  1994-09       Impact factor: 4.132

  1 in total

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