Literature DB >> 8071965

Linkage analysis of families with severe childhood autosomal recessive muscular dystrophy in Morocco indicates genetic homogeneity of the disease in north Africa.

F el Kerch1, A Sefiani, K Azibi, N Boutaleb, M Yahyaoui, A Bentahila, M C Vinet, F Leturcq, L Bachner, J Beckmann.   

Abstract

It has been previously shown in Tunisian and Algerian families that the locus for SCARMD maps to the proximal part of 13q, and in Algerian families that the disease is associated with deficiency of the 50 kDa dystrophin associated glycoprotein (50DAG). We have tested this linkage in six families from Morocco where this disease is also prevalent. In one family the 50DAG was tested and found to be negative in a muscle biopsy. Our results showed similar linkage in this country, with statistical tests indicating genetic homogeneity between the three Maghreb countries.

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Year:  1994        PMID： 8071965      PMCID： PMC1049813          DOI： 10.1136/jmg.31.4.342

Source DB:  PubMed          Journal:  J Med Genet        ISSN： 0022-2593            Impact factor:   6.318


  11 in total

1.  A second-generation linkage map of the human genome.

Authors:  J Weissenbach; G Gyapay; C Dib; A Vignal; J Morissette; P Millasseau; G Vaysseix; M Lathrop
Journal:  Nature       Date:  1992-10-29       Impact factor: 49.962

2.  Isolation and chromosomal assignment of 100 highly informative human simple sequence repeat polymorphisms.

Authors:  T J Hudson; M Engelstein; M K Lee; E C Ho; M J Rubenfield; C P Adams; D E Housman; N C Dracopoli
Journal:  Genomics       Date:  1992-07       Impact factor: 5.736

3.  Severe childhood muscular dystrophy affecting both sexes and frequent in Tunisia.

Authors:  M Ben Hamida; M Fardeau; N Attia
Journal:  Muscle Nerve       Date:  1983-09       Impact factor: 3.217

4.  Duchenne muscular dystrophy: deficiency of dystrophin-associated proteins in the sarcolemma.

Authors:  K Ohlendieck; K Matsumura; V V Ionasescu; J A Towbin; E P Bosch; S L Weinstein; S W Sernett; K P Campbell
Journal:  Neurology       Date:  1993-04       Impact factor: 9.910

5.  Deficiency of the 50 kDa dystrophin associated glycoprotein (adhalin) in severe autosomal recessive muscular dystrophies in children native from European countries.

Authors:  M Fardeau; K Matsumura; F M Tomé; H Collin; F Leturcq; J C Kaplan; K P Campbell
Journal:  C R Acad Sci III       Date:  1993-08

6.  Multilocus linkage analysis in humans: detection of linkage and estimation of recombination.

Authors:  G M Lathrop; J M Lalouel; C Julier; J Ott
Journal:  Am J Hum Genet       Date:  1985-05       Impact factor: 11.025

7.  Linkage of Tunisian autosomal recessive Duchenne-like muscular dystrophy to the pericentromeric region of chromosome 13q.

Authors:  K Ben Othmane; M Ben Hamida; M A Pericak-Vance; C Ben Hamida; S Blel; S C Carter; A M Bowcock; K Petruhkin; T C Gilliam; A D Roses
Journal:  Nat Genet       Date:  1992-12       Impact factor: 38.330

8.  Severe autosomal recessive muscular dystrophy in an extended Sudanese kindred.

Authors:  M A Salih; M I Omer; R A Bayoumi; O Karrar; M Johnson
Journal:  Dev Med Child Neurol       Date:  1983-02       Impact factor: 5.449

9.  Severe childhood autosomal recessive muscular dystrophy with the deficiency of the 50 kDa dystrophin-associated glycoprotein maps to chromosome 13q12.

Authors:  K Azibi; L Bachner; J S Beckmann; K Matsumura; E Hamouda; M Chaouch; A Chaouch; R Ait-Ouarab; A Vignal; J Weissenbach
Journal:  Hum Mol Genet       Date:  1993-09       Impact factor: 6.150

10.  Dystrophin-associated proteins are greatly reduced in skeletal muscle from mdx mice.

Authors:  K Ohlendieck; K P Campbell
Journal:  J Cell Biol       Date:  1991-12       Impact factor: 10.539
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  3 in total

1.  Mutational diversity and hot spots in the alpha-sarcoglycan gene in autosomal recessive muscular dystrophy (LGMD2D).

Authors:  A Carrié; F Piccolo; F Leturcq; C de Toma; K Azibi; C Beldjord; J M Vallat; L Merlini; T Voit; C Sewry; J A Urtizberea; N Romero; F M Tomé; M Fardeau; Y Sunada; K P Campbell; J C Kaplan; M Jeanpierre
Journal:  J Med Genet       Date:  1997-06       Impact factor: 6.318

2.  Carrier frequency of the c.525delT mutation in the SGCG gene and estimated prevalence of limb girdle muscular dystrophy type 2C among the Moroccan population.

Authors:  Fatiha El Kerch; Ilham Ratbi; Aziza Sbiti; Fatima-Zohra Laarabi; Amina Barkat; Abdelaziz Sefiani
Journal:  Genet Test Mol Biomarkers       Date:  2014-02-19

3.  Adhalin gene mutations in patients with autosomal recessive childhood onset muscular dystrophy with adhalin deficiency.

Authors:  H Kawai; M Akaike; T Endo; K Adachi; T Inui; T Mitsui; S Kashiwagi; T Fujiwara; S Okuno; S Shin
Journal:  J Clin Invest       Date:  1995-09       Impact factor: 14.808
  3 in total

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